历年诺贝尔化学奖获奖者介绍【1980】 WalterGilbert
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历年诺贝尔化学奖获奖者介绍【1980】WalterGilbert
Facts
name: WalterGilbert
Boston, MA, USA
Affiliation at the time of the award: Harvard University, Biological Laboratories, Cambridge, MA, USA
Prize motivation: "for their contributions concerning the determination of base sequences in
nucleic acids."
Prize share: 1/4
Life
Work
An organism's genome is stored in the form of long rows
of building blocks, known as nucleotides, which form DNA molecules. An organism's genome
can be mapped by establishing the order of the nucleotides within the DNA molecule. In 1976,
Allan Maxam and Walter Gilbert developed a method by which the ends of the DNA molecule
could be marked using radioactive substances. After undergoing treatment with small amounts of chemicals that react with specific nucleotides, DNA fragments of varying lengths can be obtained. After undergoing what is known as electrophoresis, the nucleotide sequences in a DNA sample
can be identified.
An organism's genome is stored in the form of long rows
of building blocks, known as nucleotides, which form DNA molecules. An organism's genome
can be mapped by establishing the order of the nucleotides within the DNA molecule. In 1976,
Allan Maxam and Walter Gilbert developed a method by which the ends of the DNA molecule
could be marked using radioactive substances. After undergoing treatment with small amounts of chemicals that react with specific nucleotides, DNA fragments of varying lengths can be obtained. After undergoing what is known as electrophoresis, the nucleotide sequences in a DNA sample
can be identified.