免疫抑制剂演化进展

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The Relay-Nobel Prize and Evolution of Immune-Modulation
时代的接力-
免疫抑制剂的演化与诺贝尔奖
(2008年11月22日 )
时代的接力
-5000年 至 -100年:祖先、壮烈医生、药师
-100年 至 -60年:战争与和平
-60年 至 -40年:肿瘤医生
person who "shall have made the most important discovery within the domain of physiology or merize in Physiology or Medicine 1901
美国欣凯公司
Nobel simply stated that prizes be given
During the preceding year, "shall have conferred the greatest
benefit on mankind" and that one part be given to the
antipyrine(安替比林),Salicylates
Aspirin 1899
欣凯
肖飞
欣凯
肖飞
时代的接力
-5000年 至 -100年:祖先、壮烈医生、药师
-100年 至 -60年:战争与和平
-60年 至 -40年:肿瘤医生

-40年 至 -20年:移植医生

-20年 至 今:风湿科医生

-40年 至 -20年:移植医生

-20年 至 今:风湿科医生

未来:肾病医生撞线?

诺贝尔奖的恰、恰、恰
美国欣凯公司
祖先
神农百草
中国炼丹术 – 长生不老 内科病 – 药师 外科病 – 理发师(放血疗法- 华盛顿)
欣凯
肖飞
欣凯 青岛
4 2020/7/5
Pain, the old enemy of human being
Emil von Behring
for his work on serum therapy, especially its application against diphtheria, by which he has opened a new road in the domain of medical science and thereby placed in the hands of the physician a victorious weapon against illness and deaths"
bleeding will diminish it”. He pleaded with the other two physicians to operate to open an airway into the general’s larynx to bypass the point of obstruction. Dr. Gustavus Brown: “had they taken no more blood from him, our good friend might have been alive now. But we were governed by the best light we had, we thought we were right, and so we are justified.”
Drug after late of 19th Century
Louis Pasteur Joseph Lister (1867) Crawford Long (1842)- use ether as
anesthesia Horace Wells- used laughing gas
(nitrous oxide) Open the abdomen (1880) Chloral hydrate(水合氯醛),

未来:肾病医生撞线?

诺贝尔奖的恰、恰、恰
美国欣凯公司
1833-1896
Alfred (Bernhard) Nobel was born October 21, 1833 in Stockholm Sweden. Nobel, who invented dynamite, endowed a $9 million fund in his will. The interest on this endowment was to be used as awards for people whose work most benefited humanity. He wanted the profit from his invention to be used to reward human ingenuity. First awarded in 1901, the Nobel Prize is still the most honored in the world.
omnipresent fever, malaria (ague)
Allopathic Medicine (对抗疗法)
Bloodletting- lancet and leeches Purging- Ipecac (吐根), Empty the bowels- Calomel (一氯化汞) Blister- mustard to make a plaster to burn
blisters
Regular doctor: “the more bitter the taste, the better the medicine.”
Heroic medicine: 大刀阔斧、壮烈的
The Death of George Washington
1799
4 times of bloodletting Blistering Calomel(一氯化汞) Dr. Elisha Dick’s advice of “He needs all his strength-
欣凯
肖飞
Drugs Before Early 19th Century
Laudanum (opium) to ease pain, Foxglove (digitalis) used as a
stimulant in heart failure Colchicine (秋水仙碱) for gout Cincona bark (quinine) against the
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