人参属药用植物组织和细胞培养的研究进展

CR3、TL R2、TL R4、D ectin21、甘露糖受体,但是由于多糖结构的多样性和复杂性,可以想象,多糖受体也是多样的,今后还会有更多的多糖受体被揭示。

多糖作用的信号转导机制也是今后研究的重要课题,其研究策略将是以作用的受体为信号传入的起始点,以某种细胞效应(如吞噬、趋化、合成或分泌细胞因子)为终点观测指标,确定其中的信号转导通路。通过研究有望发现新的药物作用靶点,为建立新的药物筛选模型提供信息。References:

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人参属药用植物组织和细胞培养的研究进展

陈　巍1,高文远13,贾　伟2,段宏泉1,肖培根3Ξ

(11天津大学药物科学与技术学院,天津　300072;21上海交通大学药学院,上海　200030;

31中国医学科学院中国协和医科大学药用植物研究所,北京　100094)

摘　要:从愈伤组织的诱导及培养、试管苗再生、悬浮培养、反应器培养及转基因器官培养等5个方面介绍了人参属药用植物组织与细胞培养的研究进展。日本和韩国已经分别实现了人参悬浮细胞和不定根培养的工业化;我国尽管已经开发了人参愈伤组织的一些产品,但在人参属药用植物组织和细胞培养的工业化方面还有一段路要走。

关键词:人参属;组织培养;细胞培养;生物反应器

中图分类号:R282121 文献标识码:A 文章编号:02532670(2005)04061605

Advances i n stud ies on tissue and cell culture i n m ed ic i na l plan ts of P anax L1 CH EN W ei1,GAO W en2yuan1,J I A W ei2,DUAN Hong2quan1,X I AO Pei2gen3

(11Co llege of Phar m aceutical Science and T echno logy,T ianjin U niversity,T ianjin300072,Ch ina;21Schoo l of Phar m acy,

Ξ收稿日期:2004206211

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