BLZ945_COA_24135_MedChemExpress
Bedaquiline fumarate_845533-86-0_DataSheet_MedChemExpress
Product Name:Bedaquiline fumarate CAS No.:845533-86-0Cat. No.:HY-14881A Product Data SheetMWt:671.58Formula:C36H35BrN2O6Purity :>98%Solubility:DMSOMechanisms:Biological Activity:Bedaquiline fumarate(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the Pathways:Anti-infection; Target:Antibacterial q (;)g y mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states ofMycobacterium tuberculosis.IC50 value:Target: anti-TB Preclinical studies have shown the efficacy of bedaquiline in terms of reduction in bacterial load and treatment duration. Phase II clinical studies have established the safety, tolerability and earliersputum conversion time in patients with MDR-TB. In 2012 FDA approved bedaquiline for treatment of MDR-TB and XDR-TB [1]. Bedaquiline possesses a unique mechanism of action that disrupts the ti it f th b t i l d i t i h h t th Cli i l t i l h b d t d References:[1]. Lakshmanan M, et al. Bedaquiline - The first ATP synthase inhibitor against multi drug resistanttuberculosis. J Young Pharm. 2013 Dec;5(4):112-115.[2]Chahine EB et al Bedaquiline:a novel diarylquinoline for multidrug-resistant tuberculosis Ann activity of the mycobacterial adenosine triphosphate synthase. Clinical trials have been conducted evaluating the use of bedaquiline in combination with a background regimen for the treatment of adults with pulmonary MDR-TB. Bedaquilin...[2]. Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. AnnPharmacother. 2014 Jan;48(1):107-15.Caution: Not fully tested. For research purposes onlyMedchemexpress LLC18 W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S AT E m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。
乙酰胺 安全技术说明书
乙酰胺安全技术说明书页码 1 / 9生效日期 02-Sep-2010修订日期 06-Mar-2018版本 1ALFAAA12589根据G B /T 16483-2008, G B /T 17519-2013一 化学品及企业标识产品描述:乙酰胺Product Description:目录编号同义字化学文摘编号(C A S N o .)分子式供应者紧急电话号码电子邮件地址推荐用途不建议的用途二 危险性概述物质或混合物的分类 致癌性类别2标签元素应急综述怀疑致癌. 吸湿的.物理状态固体外观白色气味强烈AcetamideA12589Acetic Acid Amide;Ethanamide;Methanecarboxamide.60-35-5C2 H5 N O上海齐奥化工科技有限公司上海浦东新区环科路５１５号１号楼９１０室紧急电话号码＋８６２１－５０３９６３８１传真：＋８６２１－５０３９６３８２+86 21-50940938邮件地址：产品安全部门。
实验室化学品.无资料。
警示语警告危害声明H351-怀疑致癌防范说明预防P201-使用前获特别指示P202-在明白所有安全防范措施之前请勿搬动P281-按要求使用个人防护设备响应P308+P313-如接触到或有疑虑：求医/就诊。
储存P403-存放在通风良好的地方处置P501-处置内装物/容器按照可的废弃物处理场物理和化学危害吸湿性.健康危害怀疑致癌.环境危害没有包含对环境有危险的物质或者在废水处理厂不能被降解的物质。
.由于其水溶性，可能在环境中迁移.产品溶于水，在水系统中可能会蔓延.其他危害无可用信息三 成分/组成资料组分化学文摘编号(C A S N o.)重量百分含量乙酰胺60-35-5>95四 急救措施一般建议如果症状持续，请联络医师.眼睛接触立即用大量清水冲洗至少15分钟以上，包括眼皮下面.就医治疗.皮肤接触立即以大量清水冲洗至少 15分钟.如果皮肤刺激持续，请联络医师.吸入转移到新鲜空气处。
Gelucire-14-44-SDS-MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Nov.-23-2018Print Date:Nov.-23-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :Gelucire 14/44Catalog No. :HY-Y1892CAS No. :121548-04-71.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:N/AMolecular Weight:N/ACAS No. :121548-04-74. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Pure form-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Oil)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
美国Medchemexpress化合物库(小分子库)_Medchemexpress_(MCE中国)
美国Medchemexpress化合物库（小分子库）-原装进口，现货供
应，提供组合定制服务
品牌：Medchemexpress （MCE）
保存条件：-20℃
供应商：MCE中国
数量：大量
保质期：2年
Size：
Pre-dissolved DMSO/Solid（Or dry solid）
100 uL/well (10 mM solution)
200 uL/well (10 mM solution)
MedChemExpress (MCE)专注于各种抑制剂、调节剂、API、天然产物及化合物库，总部位于美国新泽西。
MCE经过十年努力已成为全球生物活性小分子领域的一流供应商。
MedChemExpress(MCE)产品涵盖近20个热门研究领域，1000多个细分靶点，超过3000个现货抑制剂、拮抗剂和激动剂。
相关的应用成果已发表于Nature、Cell等国际知名杂志，在全球20余个国家地区设有代理机构。
上海皓元生物医药科技有限公司(MCE 中国) 是MedChemExpress (MCE) 亚洲总代理。
MCE化合物库涵盖20余种不同的类型，超过2500个化合物，进口原装，
现货供应，提供详实的生物活性信息、化学结构信息、质控图谱（NMR和HPLC 等）。
还可根据您的实际研究需要，为您度身定制任意组合、规格、布板的特殊化合物库。
/screening-libraries.html
现有特色化合物库有：。
植物病害诊断试剂盒
植物病害诊断试剂盒美国阿格迪agdia 公司是全球最大的植物病害诊断试剂生产商，产品品种最多，可检测项目多达200多个。
包装规格最全,不同的包装规格适合不同规模的实验室。
从中您一定能发现适合您使用的产品。
选购试剂说明，请仔细阅读。
1，kit, 订货号PSAxxxxx/xxxx 或PSPxxxxx/xxxx 为完整的试剂盒包装，包括样品提取缓冲液、包被好抗体的微孔板（可拆分）、酶标记物、稀释液、缓冲液、底物发色剂、阳性质控（如果应该供应）。
特别注明Indirect ELISA 方法的kit 包括未包被的微孔板及联接用的抗体，所含有的其他组分同上。
2， Reagent Set, 订货号SRAxxxxx/xxxx ,XRAxxxxx/xxxx或SRPxxxxx/xxxx 只含有未包被的微孔板、包被需要的抗体或联接用的抗体、酶标记物。
其他试剂如样品提取缓冲液、稀释液、缓冲液、底物发色剂、质控物需另外订购或自己配制。
我公司销售原厂的上述试剂，详见目录。
3， Bacterial Reagent Set, 订货号BRAxxxxx/xxxx 只含有未包被的微孔板、包被需要的抗体或联接用的抗体、酶标记物。
其他试剂如样品提取缓冲液、稀释液、缓冲液、底物发色剂、质控物需另外订购或自己配制。
我公司销售原厂的上述试剂，详见目录。
4， Bacterial ID订货号BIDxxxxx/xxxx 为完整的试剂盒包装，包括样品提取缓冲液、包被好抗体的微孔板（可拆分）、酶标记物、稀释液、缓冲液、底物发色剂、质控（如果应该供应）。
用于鉴定培养基中或有病症植物提取液中的细菌。
操作简便快速。
5， PS A或SR A中的A代表碱性磷酸酶标记；PS P或SR P中的P代表过氧化物酶标记。
6， Immunostrip test, 为检试纸条，操作简单，几分钟内得到结果，非常适合于现场检测。
该试条必须与相应的样品提取缓冲液配套使用。
实验室需要单独购买该样品提取缓冲液，详见目录。
溴乙酸乙酯-危险化学品安全标签
溴乙酸乙酯Ethyl bromoacetate 浓度或浓度范围：溴乙酸乙酯：100%
危险！
吞咽致命。
皮肤接触致命。
吸入致命。
【预防措施】
——P264作业后彻底清洗。
——P270使用本产品时不要进食、饮水或吸烟。
——P262严防进入眼中、接触皮肤或衣服。
——P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
——P260不要吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
——P271只能在室外或通风良好处使用。
——P284[在通风不足的情况下]戴呼吸防护装置
【事故响应】
——P301+P310如误吞咽：立即呼叫解毒中心/医生
——P330漱口。
——P302+P352如皮肤沾染：用水充分清洗。
——P310立即呼叫解毒中心/医生
——P361+P364立即脱掉所有沾染的衣服，清洗后方可重新使用
——P304+P340如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
【安全储存】
——P405存放处须加锁。
——P403+P233存放在通风良好的地方。
保持容器密闭。
【废弃处置】
——P501按当地法规处置内装物/容器。
请参阅化学品安全技术说明书
供应商：电话：地址：邮编：
化学事故应急咨询电话：。
2013年6月20日发布最新影响因子IF_完整版
Total Cites Impact5-Year ImmediacyArticles (linked to journal informationFactor Impact Index1439CA-CANCER J CLIN0007-923513722153.45988.5527.0425 6399NEW ENGL J MED0028-479324560551.65850.80712.667360 7457REV MOD PHYS0034-68613572044.98251.882 6.47846 1675CHEM REV0009-266511259641.29845.79514.335176 6266NAT REV GENET1471-00562335841.06336.4 6.31470 5693LANCET0140-673616692239.0636.4279.556313 6278NATURE0028-0836********.59738.1599.243869 6269NAT REV MOL CELL BIO1471-00723134137.16244.026 5.98565 668ANNU REV IMMUNOL0732-05821596336.55643.7428.42928 6247NAT MATER1476-11224634835.74942.3768.411141 6240NAT GENET1061-40368118335.20934.52 5.511225 6260NAT REV CANCER1474-175X326283539.361 6.33369 277ADV PHYS0001-8732484934.29431.1670.8577 6267NAT REV IMMUNOL1474-173********.12935.851 4.83165 6263NAT REV DRUG DISCOV1474-177********.07833.2058.65143 6232NAT BIOTECHNOL1087-01563872832.43832.1827.08792 1565CELL0092-867417876231.95734.366 6.499415 6272NAT REV NEUROSCI1471-003X2693831.67335.888 5.06562 6250NAT NANOTECHNOL1748-33872192031.1736.011 5.876121 7624SCIENCE0036-807550848931.02733.587 6.691832 6948PHYSIOL REV0031-93332253730.17438.707 2.53839 5608JAMA-J AM MED ASSOC0098-748412150429.97829.2738.504232 652ANNU REV BIOCHEM0066-41541942027.68131.964 4.31232 6252NAT PHOTONICS1749-48851399327.25431.5677.492120 7140PROG POLYM SCI0079-67001445726.38331.706 4.60756 3430IEEE ENG MED BIOL0739-5175291326.3038.0190 6245NAT IMMUNOL1529-29083246526.19925.005 4.961128 677ANNU REV PATHOL-MECH1553-4006232225.79419.915 6.38918 1599CELL STEM CELL1934-59091259325.31527.361 4.336122 5696LANCET ONCOL1470-20451700525.11721.856 6.536153 1678CHEM SOC REV0306-00124764624.89230.1817.997390 1500CANCER CELL1535-61082220024.75527.059 4.465114 5695LANCET NEUROL1474-44221516023.91722.959 4.47289 682ANNU REV PLANT BIOL1543-50081343823.65429.248 3.18527 6249NAT METHODS1548-70911924123.56523.231 4.404151 651ANNU REV ASTRON ASTR0066-4146824023.33334.261 2.21414 7125PROG MATER SCI0079-6425592123.19422.3337.21723 6912PHYS REP0370-157********.92922.99 6.69843 6248NAT MED1078-89565735022.86426.441 5.763186 6268NAT REV MICROBIOL1740-152********.4923.227 4.02969 6854PHARMACOL REV0031-69971033122.34522.114 2.33336 5764LIVING REV RELATIV1433-8351141722.33316.417 2.81811 6234NAT CHEM1755-4330865221.75723.02 5.532126 678ANNU REV PHARMACOL0362-1642720521.54321.6447.26926 15ACCOUNTS CHEM RES0001-48424211220.83324.633 5.295207 6233NAT CELL BIOL1465-73923222120.76120.691 3.97132 674ANNU REV NEUROSCI0147-006X1263820.61431.028 3.11526 5694LANCET INFECT DIS1473-30991047119.96618.095780 3581IMMUNITY1074-76133254619.79520.722 3.713164 680ANNU REV PHYSIOL0066-4278791419.54718.952 4.90521 6253NAT PHYS1745-24731800419.35219.367 6.854137 1098BEHAV BRAIN SCI0140-525X640218.57123.173 2.286144480J CLIN ONCOL0732-183X12867918.03817.255 4.836597 655ANNU REV CELL DEV BI1081-0706886617.98319.8060.78628 2458ECOL LETT1461-023X1753317.94918.495 1.403154 6221NANO TODAY1748-0132294417.68918.1920.78437 666ANNU REV GENET0066-4197677217.43621.7890.31232 1843CLIN MICROBIOL REV0893-85121205517.31319.065 2.21428 1422BRIT MED J1756-183********.21515.887.756328 6045MICROBIOL MOL BIOL R1092-2172907916.41717.718 1.51729 931ASTROPHYS J SUPPL S0067-00492476416.23814.437 3.074162 671ANNU REV MATER RES1531-7331525916.17914.4950.66718 8125TRENDS COGN SCI1364-66131571716.00816.845 4.05654 6356NEURON0896-62736952615.76616.403 2.603348 7191PSYCHOL BULL0033-29093081415.57519.676 2.31638 6271NAT REV NEUROL1759-4758229515.51813.994 1.65452 8126TRENDS ECOL EVOL0169-53472427915.38917.112 2.97476 7907SURF SCI REP0167-5729411515.33322.2817.758 6126MOL CELL1097-27654781815.2814.902 2.818296 683ANNU REV PSYCHOL0066-43081063515.26526.624 4.81822 7023PLOS MED1549-16761482015.25316.426 3.235115 6251NAT NEUROSCI1097-62564251915.25116.412 2.882228 1770CIRCULATION0009-732215228115.20215.385 2.98592 658ANNU REV CONDEN MA P1947-545462415.13915.139 5.13315 7122PROG ENERG 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6190MUCOSAL IMMUNOL1933-021*******.119 1.65767 3826INT J EPIDEMIOL0300-577114451 6.9827.001 3.281128 4205J AM ACAD CHILD PSY0890-856716470 6.977.148 2.0196 6223NANOMED-NANOTECHNOL1549-96343097 6.937.647 1.263160 2228CURR TOP DEV BIOL0070-21532246 6.912 6.4670.76242 6685P IEEE0018-921918840 6.9117.6940.697195 3200GLOBAL CHANGE BIOL1354-101318398 6.917.819 1.3297 6534OCEANOGR MAR BIOL0078-32182142 6.9099.8790.56 5139J NEUROSCI0270-6474160915 6.9087.8690.9781668 3362HUM BRAIN MAPP1065-947113379 6.8787.032 1.451226 3398HYPERTENSION0194-911X32323 6.873 6.984 1.588342 6518OBES REV1467-78815154 6.877.021 1.436101 6008METAB ENG1096-71762855 6.859 6.696 1.34772 1864CLIN PHARMACOL THER0009-923614263 6.846 6.349 1.995200 1627CEREB CORTEX1047-321121409 6.8287.463 2.05258 3224GREEN CHEM1463-926215554 6.828 6.992 1.269449 6929PHYS TODAY0031-92283738 6.762 5.263 1.51437 275ADV ORGANOMET CHEM0065-3055841 6.758.94103 6949PHYSIOLOGY1548-92132500 6.758.388 1.13829 6407NEW PHYTOL0028-646X26842 6.736 6.888 1.373378 929ASTROPHYS J0004-637X191940 6.733 5.945 2.0473075 1764CIRC-CARDIOVASC GENE1942-325X1641 6.728 6.398 1.17182 6921PHYS REV X2160-3308414 6.711 6.737 2.22571 6158MOL ONCOL1574-78911193 6.701 6.3790.91760 1768CIRC-HEART FAIL1941-32892007 6.684 6.67 1.41993 1309BMC MED1741-70152691 6.679 6.413 1.275109 1820CLIN GASTROENTEROL H1542-35658295 6.648 6.108 1.458179 6561ONCOTARGET1949-25531450 6.636 6.636 1.316114 2177CURR OPIN COLLOID IN1359-02944670 6.6297.0360.88443 2862EXPERT REV MOL MED1462-39941734 6.6230.78919 1417BRIT J PSYCHIAT0007-125021472 6.6067.112 1.872117 1019B AM METEOROL SOC0003-000711821 6.5917.704 2.48778 5280J PHYS CHEM LETT1948-71858575 6.585 6.651 1.301632 6902PHYS LIFE REV1571-0645659 6.583 6.699.45511 6990PLANT J0960-741232497 6.5827.113 1.5333456997PLANT PHYSIOL0032-088962407 6.5557.084 1.313469 5605JACC-CARDIOVASC INTE1936-87983378 6.552 6.834 1.603126 2396DRUG DISCOV TODAY1359-64468855 6.551 6.89 1.177158 271ADV MICROB PHYSIOL0065-29111006 6.545 6.267 1.25 1766CIRC-CARDIOVASC INTE1941-76401534 6.543 6.239 1.23797 1292BMC BIOL1741-70072631 6.531 6.384 1.69559 405AM J CLIN NUTR0002-916548233 6.5047.196 1.2325 2325DIABETOLOGIA0012-186X24906 6.487 6.772 1.749339 6150MOL INTERV1534-03841243 6.4818.0310 1490CAN MED ASSOC J0820-394611869 6.4657.53 1.766124 4906J INTERN MED0954-******** 6.455 5.913 1.609110 4465J CLIN ENDOCR METAB0021-972X68170 6.43 6.568 1.087809 6203MUTAT RES-REV MUTAT1383-57422736 6.4268.202122 6368NEUROPSYCHOL REV1040-73081611 6.427.5260.86229 353AIDS0269-937023034 6.407 6.131 1.679265 8059TOP ORGANOMETAL CHEM1436-60021152 6.384 1.76221 1643CHEM COMMUN1359-7345122728 6.378 6.226 1.533173 1557CATAL REV0161-49402529 6.37510.1750.8899 2780EUR RESPIR J0903-193625962 6.355 6.32 1.82317 222ADV CANCER RES0065-230X1890 6.351 5.5120.57121 8074TRAC-TREND ANAL CHEM0165-99367327 6.351 6.7610.92138 930ASTROPHYS J LETT2041-820545993 6.345 1.687670 7279RADIOLOGY0033-841945413 6.339 6.7380.832381 873ARTERIOSCL THROM VAS1079-564231851 6.338 6.986 1.097370 636ANN SURG0003-493236761 6.3298.264 1.15301 6973PLANT BIOTECHNOL J1467-76443136 6.279 5.813 1.04101 6139MOL ECOL0962-108330411 6.275 6.792 1.369445 2110CRIT REV TOXICOL1040-84442955 6.253 5.9720.94335 6339NEUROIMAGE1053-811961770 6.2527.063 1.2911222 2595ENVIRON INT0160-41209059 6.248 6.1220.935199 5339J PSYCHIATR NEUROSCI1180-48822253 6.242 6.473 1.64734 6226NANOSCALE2040-33647835 6.233 6.262 1.1671015 7886STUD MYCOL0166-06161237 6.231 6.813 4.1676 6869PHILOS T R SOC B0962-843626581 6.237.298 3.522289 2310DEVELOPMENT0950-199151191 6.208 6.888 1.258434 7648SEMIN CELL DEV BIOL1084-95215613 6.202 6.51 1.034116 3764INT J CANCER0020-713644529 6.198 5.474 1.39738 4915J INVEST DERMATOL0022-202X23976 6.193 6.065 1.898264 471AM J TRANSPLANT1600-613516088 6.192 6.014 1.506348 6318NEURO-ONCOLOGY1522-85173845 6.18 5.9470.694157 231ADV COLLOID INTERFAC0001-86867115 6.1698.01 1.3250 6320NEUROBIOL AGING0197-458015479 6.166 6.098 1.583537 5604JACC-CARDIOVASC IMAG1936-878X2977 6.164 6.703 1.717113 2080CORTEX0010-94525265 6.161 5.042 2.745106 7864STROKE0039-249952524 6.158 6.831 1.086567 1640CHEM BIOL1074-55219695 6.157 6.097 1.486144 6621ORG LETT1523-706073440 6.142 5.563 1.5721608 4378J BONE MINER RES0884-043122111 6.128 6.227 1.101257 6165MOL PLANT1674-20522346 6.126 5.77 1.585118 2094CRIT CARE MED0090-349332733 6.124 6.401 2.614363 2371DIVERS DISTRIB1366-95164336 6.122 5.7430.935107 1863CLIN PHARMACOKINET0312-******** 6.109 5.4860.98154 8313WHO TECH REP SER0512-******** 6.1 3.2560.35714 8039THROMB HAEMOSTASIS0340-624517392 6.094 4.782 1.3462465510J THROMB HAEMOST1538-793314645 6.081 6.176 1.17265 5876MATER TODAY1369-70213769 6.0718.677 1.97744 1578CELL DEATH DIS2041-48891481 6.044 6.0440.565191 4548J COSMOL ASTROPART P1475-751613656 6.036 5.295 2.387555 1523CANCER TREAT REV0305-73724233 6.024 6.246 1.458107 7131PROG NUCL MAG RES SP0079-65651993 6.022 6.065 1.38918 1285BLOOD REV0268-960X17706 6.6620.76939 7877STRUCTURE0969-212612441 5.994 6.081 1.466191 2519EMERG INFECT DIS1080-604021567 5.993 6.312 1.689244 322AGEING RES REV1568-16371965 5.953 6.549 1.43941 7706SIAM REV0036-14455051 5.9528.4140.40922 1763CIRC-ARRHYTHMIA ELEC1941-31492173 5.947 6.434 1.175143 2108CRIT REV SOLID STATE1040-8436744 5.9477.368110 1543CARDIOVASC RES0008-636320689 5.94 6.113 1.689222 3241HAEMATOL-HEMATOL J0390-607811392 5.935 6.002 1.454251 7654SEMIN IMMUNOL1044-53233190 5.9267.250.89146 6031METHODS ECOL EVOL2041-210X822 5.92460.854123 203ADDICT BIOL1355-62151977 5.914 5.322 1.01193 1081BASIC RES CARDIOL0300-84283292 5.904 5.362 1.16772 6390NEUROTHERAPEUTICS1933-72131923 5.904 5.720.90563 381ALLERGY0105-453812173 5.883 5.983 1.58193 4422J CELL SCI0021-953340261 5.877 6.375 1.032535 1391BREAST CANCER RES1465-542X7547 5.872 6.2640.82172 1528CARBON0008-622332742 5.868 6.35 1.197674 2915FISH FISH1467-29601846 5.8557.326 1.53826 1699CHEST0012-369244596 5.854 6.42 3.394307 4871J INFECT DIS0022-189942783 5.848 5.914 1.556493 2189CURR OPIN LIPIDOL0957-96723620 5.839 5.7380.92264 6966PIGM CELL MELANOMA R1755-14713385 5.839 5.434 1.39768 1685CHEM-EUR J0947-653960788 5.831 5.623 1.2411916 717APPL CATAL B-ENVIRON0926-337323011 5.825 6.0310.965480 4486J CLIN PSYCHIAT0160-668917639 5.812 5.6390.726157 1765CIRC-CARDIOVASC IMAG1941-96511650 5.795 6.579 1.17984 5924MAYO CLIN PROC0025-61969444 5.79 5.638 1.44109 4413J CATAL0021-951734516 5.787 6.249 1.025284 5164J NUCL MED0161-550521262 5.774 6.4020.934243 2597ENVIRON MICROBIOL1462-291213228 5.756 5.943 1.455242 2626EPIDEMIOLOGY1044-39838979 5.738 6.241 2.12588 8328WIRES COMPUT MOL SCI1759-0876570 5.738 5.738 3.51856 2539ENDOSCOPY0013-726X8401 5.735 5.355 1.514144 4048INT REV IMMUNOL0883-******* 5.733 4.140.44829 324AGING CELL1474-97184134 5.705 6.415 1.485130 2885FASEB J0892-663839540 5.704 6.222 1.13462 1895COCHRANE DB SYST REV1469-493X34230 5.703 6.5120.728977 5027J MED GENET0022-259311563 5.703 5.793 1.353116 5687LAB CHIP1473-019716485 5.697 6.136 1.256617 510ANAL CHEM0003-270096794 5.695 5.7690.9481479 6697P ROY SOC B-BIOL SCI0962-845237539 5.683 5.832 1.224624 8330WIRES NANOMED NANOBI1939-5116983 5.681 6.34 1.08547 1767CIRC-CARDIOVASC QUAL1941-77051551 5.658 5.647 1.43100 7369RETROVIROLOGY1742-46903084 5.657 4.857 1.505107 6713PAIN0304-395929370 5.644 6.125 1.264269 3917INT J NEUROPSYCHOPH1461-14574003 5.641 5.0920.805123 1530CARCINOGENESIS0143-333421223 5.635 5.5570.9553106383NEUROSCIENTIST1073-85843259 5.633 6.417 1.35645 7327RENEW SUST ENERG REV1364-032110347 5.627 6.5770.803584 6321NEUROBIOL DIS0969-996111288 5.624 5.482 1.493296 5925MBIO2150-75111260 5.621 5.621 1.536151 4817J HIGH ENERGY PHYS1126-670852898 5.618 4.712 2.6581861 1589CELL MOL LIFE SCI1420-682X17974 5.615 6.359 1.072290 5022J MED CHEM0022-262359227 5.614 5.383 1.225890 1362BRAIN BEHAV IMMUN0889-15916137 5.612 5.698 1.082147 6124MOL CANCER THER1535-716314654 5.599 5.72 1.201259 1873CLIN REV ALLERG IMMU1080-05491685 5.59 3.955 1.30662 7194PSYCHOL MED0033-291716680 5.587 6.1480.913230 2098CRIT REV BIOCHEM MOL1040-92382729 5.5788.032 1.23330 6583OPHTHALMOLOGY0161-642026007 5.563 5.777 1.065354 3107GENET MED1098-36004119 5.56 5.035 1.554121 1259BIOTECHNOL BIOFUELS1754-6834903 5.552 6.4590.35288 2401DRUG METAB REV0360-25322342 5.538 5.843 1.2516 291ADV SYNTH CATAL1615-415015502 5.535 5.323 1.109404 5793MACROMOLECULES0024-929797921 5.521 5.209 1.0941069 6176MON NOT R ASTRON SOC0035-871196083 5.521 5.009 1.7942574 4853J IMMUNOL0022-1767129339 5.52 5.6730.951289 7791SPACE SCI REV0038-63087134 5.519 5.1060.921114 8135TRENDS PARASITOL1471-49224819 5.513 4.878 1.11470 943ATMOS CHEM PHYS1680-731622919 5.51 5.556 1.176723 3765INT J CARDIOL0167-527312371 5.509 4.125 1.681326 2133CSH PERSPECT MED2157-1422211 5.5 5.5 1.099142 6511NUTR RES REV0954-******** 5.5 5.2020.11817 3323HIPPOCAMPUS1050-96318046 5.492 5.484 1.603184 2798EUROSURVEILLANCE1560-79175236 5.491 1.34188 3492IEEE T FUZZY SYST1063-67066237 5.484 4.8850.58193 6155MOL NEUROBIOL0893-******** 5.471 5.5350.782101 6289NEOPLASIA1522-80025715 5.47 5.077 1.208120 4096INVEST RADIOL0020-99965353 5.46 4.444 1.392102 1090BBA-GENE REGUL MECH1874-93994518 5.456 4.338 1.217129 2201CURR OPIN PHARMACOL1471-48925198 5.443 6.4470.765102 50ACS CHEM BIOL1554-89293417 5.442 5.478 1.387230 2206CURR OPIN SOLID ST M1359-02862508 5.4387.3290.91323 1248BIOSENS BIOELECTRON0956-566322068 5.437 5.389 1.105448 4592J ECOL0022-047713938 5.431 6.199**** ****BIOESSAYS0265-92478695 5.423 4.814 1.291134 4448J CHILD PSYCHOL PSYC0021-963012841 5.422 6.2350.976127 2194CURR OPIN NEUROL1350-75404449 5.416 5.0350.80497 4427J CEREBR BLOOD F MET0271-678X14671 5.398 5.66 1.093194 4439J CHEM THEORY COMPUT1549-961811067 5.389 5.936 1.067507 7655SEMIN IMMUNOPATHOL1863-22971214 5.379 5.668 1.6958 6128MOL CELL BIOL0270-730667211 5.372 5.745 1.036415 1200BIOMACROMOLECULES1525-779724209 5.371 5.750.721480 4261J ANTIMICROB CHEMOTH0305-745320364 5.338 4.686 1.257428 4466J CLIN EPIDEMIOL0895-435615399 5.332 5.120.711149 5284J PHYS G NUCL PARTIC0954-******** 5.326 2.812 1.37184 1165BIOINFORMATICS1367-480351753 5.323 6.9110.729728 3052FUNGAL DIVERS1560-27451665 5.319 4.2 1.73653 6993PLANT MOL BIOL REP0735-******** 5.319 4.020.293157 2152CURR GENE THER1566-52321362 5.318 4.3220.6141 4224J AM MED DIR ASSOC1525-86102480 5.302 3.912 1.3431781398BRIEF BIOINFORM1467-54633073 5.2987.51 1.27658 426AM J KIDNEY DIS0272-638619101 5.294 5.417 1.724199 2813EXERC SPORT SCI REV0091-63312207 5.283 4.841127 5781MABS-AUSTIN1942-0862765 5.275 4.8240.78565 3012FREE RADICAL BIO MED0891-584931156 5.271 5.969 1.033450 49ACS CATAL2155-54351461 5.265 5.265 1.222315 2533ENDOCR-RELAT CANCER1351-00884611 5.261 5.1720.73494 6224NANOMEDICINE-UK1743-58892713 5.26 6.2360.746114 4068INTENS CARE MED0342-464214780 5.258 5.036 1.074215 2611ENVIRON SCI TECHNOL0013-936X92385 5.257 5.8650.7921608 4364J BIOMED NANOTECHNOL1550-70332198 5.256 4.366 1.491108 6110MODERN PATHOL0893-395210184 5.253 5.058 1.371175 224ADV CATAL0360-05641399 5.25 5.28602 226ADV CHEM PHYS0065-23852306 5.25 4.250.71746 1066B WORLD HEALTH ORGAN0042-968611151 5.25 6.076 1.04295 2708EUR J HEART FAIL1388-98425824 5.247 4.738 1.469147 2770EUR PHYS J C1434-604411003 5.247 3.603 2.222406 1576CELL CYCLE1538-410115668 5.243 4.806 1.079444 4679J EXP BOT0022-095724541 5.242 5.5420.903493 7814SPORTS MED0112-16427069 5.237 5.7550.64164 3202GLOBAL ENVIRON CHANG0959-37804587 5.236 6.9010.88285 7047POLYM CHEM-UK1759-99543328 5.231 5.231 1.305397 3018FRONT AGING NEUROSCI1663-4365392 5.224 5.1690.72733 3933INT J OBESITY0307-056518052 5.221 5.522 1.174213 852ARCH TOXICOL0340-57614824 5.215 3.990.94149 3376HUM MUTAT1059-779411082 5.213 5.761 1.754224 3077GASTROINTEST ENDOSC0016-510718497 5.21 5.276 2.32297 1524CANCER-AM CANCER SOC0008-543X62757 5.201 5.693 1.108674 2205CURR OPIN RHEUMATOL1040-87113701 5.191 4.256 1.04589 1688CHEMCATCHEM1867-38802718 5.181 5.3070.941255 2315DIABETES OBES METAB1462-89024587 5.181 4.415 1.491173 2463ECOLOGY0012-965850217 5.175 6.3720.583283 3497IEEE T IND ELECTRON0278-004617404 5.165 5.0780.943470 528ANESTHESIOLOGY0003-302222547 5.163 5.302 1.959219 5065J MOL CELL CARDIOL0022-282811674 5.148 5.034 1.478232 7200PSYCHONEUROENDOCRINO0306-45309603 5.137 5.926 1.091198 6978PLANT CELL ENVIRON0140-779114009 5.135 5.861 1.639158 6122MOL CANCER1476-45984995 5.134 5.0970.3686 6849PHARMACOGENOMICS J1470-269X2084 5.134 4.455 1.12365 2444ECOGRAPHY0906-******** 5.124 5.7910.925120 2179CURR OPIN DRUG DISC1367-67331825 5.121 4.1080 3657INFLAMM BOWEL DIS1078-09988279 5.119 5.233 1.161261 6801PEDIATRICS0031-400559035 5.119 5.930.951687 2702EUR J EPIDEMIOL0393-******** 5.118 4.1160.49489 2729EUR J NUCL MED MOL I1619-707010881 5.114 4.821 1.202198 4805J HEART LUNG TRANSPL1053-24987139 5.112 3.6270.975159 5104J NATL COMPR CANC NE1540-14051890 5.1120.522115 7318REMOTE SENS ENVIRON0034-425724105 5.103 6.1440.987388 7724SLEEP0161-810514444 5.1 6.175 1.068162 2099CRIT REV BIOTECHNOL0738-******** 5.095 5.9660.95221 604ANN MED0785-38903665 5.094 4.640.76397 74ACTA BIOMATER1742-706110169 5.093 5.3780.903453 1575CELL COMMUN SIGNAL1478-811X520 5.0930.20539 7499RNA1355-838211854 5.088 5.43 1.01201920ASTRON ASTROPHYS0004-6361101305 5.084 4.422 1.4511892 1404BRIT J CANCER0007-092038414 5.082 5.2060.827561 5569J VIROL0022-538X93028 5.076 4.893 1.2581559 1831CLIN J AM SOC NEPHRO1555-90418449 5.068 5.445 1.1240 1415BRIT J PHARMACOL0007-118828119 5.067 4.898 1.288539 3198GLIA0894-149110371 5.066 5.406 1.38166 2105CRIT REV MICROBIOL1040-841X1335 5.065 5.615 1.09521 2675EUR HEART J SUPPL1520-765X977 5.065 1.817 1.910 2681EUR J CANCER0959-804921316 5.061 5.2570.991343 208ADV AGRON0065-21132753 5.06 5.5120.45824 5336J PROTEOME RES1535-389317943 5.056 5.2230.882544 3916INT J NEURAL SYST0129-0657992 5.054 3.6460.45735 1975COMPR REV FOOD SCI F1541-43371046 5.053 4.7920.26730 3273HEART RHYTHM1547-52717449 5.045 4.719 2.089237 1775CLADISTICS0748-30073315 5.043 6.183 1.86730 7737SOC COGN AFFECT NEUR1749-50161980 5.042 6.78 1.347101 3173GEOSCI MODEL DEV1991-959X626 5.03 4.50.84691 6186MRS BULL0883-******** 5.024 5.590.569116 3269HEART1355-603713857 5.014 4.769 1.667243 48ACS APPL MATER INTER1944-82448635 5.008 5.040.683953 2491ELECTROANAL CHEM0070-977837757.50.254 216ADV APPL MICROBIOL0065-21641233 4.974 4.7840.33321 4045INT REV CEL MOL BIO1937-6448825 4.973 4.9440.40849 2713EUR J IMMUNOL0014-298020974 4.97 4.7680.739322 663ANNU REV ENV RESOUR1543-59381402 4.9687.25018 923ASTRON J0004-625634668 4.965 4.571 1.162334 6154MOL MICROBIOL0950-382X37172 4.961 5.099 1.123359 2351DIS MODEL MECH1754-84031212 4.959 5.0090.98988 1407BRIT J HAEMATOL0007-104820668 4.942 4.7260.891266 4497J COMB CHEM1520-47662925 4.933 3.1020 5789MACROMOL RAPID COMM1022-133612103 4.929 4.6180.916261 5129J NEUROL NEUROSUR PS0022-305023923 4.924 5.144 1.69187 2628EPIGENETICS-US1559-22942289 4.92 4.8810.773150 4050INT REV PHYS CHEM0144-235X1524 4.92 5.595 2.23113 1119BEST PRACT RES CL EN1521-690X2576 4.912 5.1810.25866 1091BBA-MOL BASIS DIS0925-44396277 4.91 4.932 1.248202 5451J STAT SOFTW1548-76602629 4.91 5.9070.75377 5356J R SOC INTERFACE1742-56895016 4.907 5.1650.806320 4206J AM ACAD DERMATOL0190-962219760 4.906 4.5150.896280 1518CANCER PREV RES1940-62073114 4.891 5.126 1.401142 2187CURR OPIN INFECT DIS0951-******** 4.87 4.610.83987 2846EXPERT OPIN DRUG DEL1742-52472829 4.869 5.1330.495103 469AM J SURG PATHOL0147-518516422 4.868 4.8570.798223 7021PLOS COMPUT BIOL1553-735811758 4.867 5.9390.824507 6837PFLUG ARCH EUR J PHY0031-67689307 4.866 3.9280.853129 2810EVOLUTION0014-382030585 4.864 5.4020.939313 4347J BIOGEOGR0305-027010682 4.863 4.979 1.399183 3042FUNCT ECOL0269-84639681 4.861 5.3930.882153 2231CURR TOP MICROBIOL0070-217X4958 4.86 4.744 5.05319 1875CLIN SCI0143-52218069 4.859 4.843 1.2110 174ACTA PSYCHIAT SCAND0001-690X11048 4.857 4.625198 386ALTERN MED REV1089-51591288 4.857 5.0340.56 250ADV GENET0065-26601198 4.85 4.102010 4253J ANIM ECOL0021-879012354 4.841 5.1660.881134。
国内在研1.1类糖尿病新药
CXHL1000720鲁
CXHL1000719鲁
化药
化药
新药
新药
1.1 2011-05-16 山东轩竹医药
1.1 2011-05-16 科技有限公司
瑞格列汀二甲双胍片(II) CXHL1300534苏 磷酸瑞格列汀 磷酸瑞格列汀片 CXHL0900102苏 CXHL0900103苏
Байду номын сангаас
在研1.1类糖尿病新药申报信息
药品名称
苯甲酸复格列汀
受理号码
CXHL1200845渝
药品 类型 化药 化药 化药 化药
申请 类型 新药 新药 新药 新药
注册 分类
承办日期
国内在研1.1类糖尿病新药
西安万隆制药股份有限公司 王震 2013-10-26
目录
1. 维格列汀---北京诺华制药有限公司 2. 酒石酸艾格列汀----山东绿叶制药有限公司 3. 托西酸贝格列汀----江苏豪森药业股份有限公司 4.沙格列汀片--- 阿斯利康(无锡)贸易有限公司 5.磷酸瑞格列汀----江苏恒瑞医药股份有限公司 6.苯甲酸复格列汀-----重庆复创医药研究有限公司 7.盐酸依格列汀----山东轩竹医药科技有限公司
在研1.1类糖尿病新药申报信息
药品名称 维格列汀 维格列汀片 维格列汀片 维格列汀片 受理号码 JXHL0600218国 CXHS0700083京 CXHL0501674京 CXHL0501675京 药品 类型 化药 化药 化药 化药 化药 化药 化药 申请 类型 进口 新药 新药 新药 新药 新药 新药 注册 分类 1.1 1.1 1.1 1.1 1.1 1.1 1.1 承办 日期 2006-08-17 2007-06-25 北京诺华制药 2005-09-01 2005-09-01 2013-07-30 2013-07-30 2013-07-30 山东绿叶制药 有限公司 有限公司 企业名称
94种化合物高效液相色谱分析中紫外吸收波长的选择
农 药AGROCHEMICALS 第49卷第8期2010年8月Vol. 49, No. 8Aug. 201094种化合物高效液相色谱分析中紫外吸收波长的选择吴国旭1，翟立红2，毕富春3(1.天津渤海职业技术学院 环境工程系，天津 300402； 2.河北省廊坊市诺农生物工程有限公司，河北 廊坊 065000；3.南开大学 元素有机化学研究所，天津 300071)摘要：研究了94种化合物在高效液相色谱分析中对紫外光波吸收波长的选择，并找出了这些化合物的最大吸收波长和适宜分析波长。
化合物的残留分析可选择最大紫外吸收波长；化合物常规定量分析可选择适宜分析波长，它可以简化操作步骤及减少分析时间。
关键词：化合物；紫外吸收波长；高效液相色谱法中图分类号：TQ450.7 文献标志码：A 文章编号：1006-0413(2010)08-0581-04Selection of UV Absorption Wavelength for 94 Pesticide Analysis by HPLCWU Guo-xu 1, ZHAI Li-hong 2, BI Fu-chun3(1.The Department of Environmental Engineering, Tianjin Bohai College of Professional Technology, Tianjin 300402, China;2.Hebei Langfang Nuonong Bioengineering Co., Ltd., Langfang 065000, Hebei, China;3.Institute of Elemental Organic Chemistry, Nankai University, Tianjin 300071, China)Abstract: The selection of UV absorption wavelength of 94 chemicals by HPLC was studied. The maximum and appropriate absorption wavelengths of the chemicals were chose out. The maximum absorption wavelengths were appropriate for the residue analysis of chemicals. The appropriate absorption wavelengths were appropriate for quantitative analysis of chemicals. The utilizing appropriate absorption wavelengths of chemicals could simply operating steps of analytical methods and reduce operating time. Key words: chemicals; UV absorption wavelength; HPLC随着科学技术的发展，高效液相色谱仪在农药分析中广范使用，特别是紫外可变波长检测器的普及，使农药分析技术得到极大提高。
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药物GLP认证目录(2022版)
中国药科大学
（新药安全评价
研究中心）
单次和多次给药毒性试验（非啮齿类，灵长类）
GLP21007126
广州医药研究总院有限公司（药物非临床评价研究中心）
1.生殖毒性试验（Ш段）
2.致癌试验
GLP21008127
西咸新区国睿一诺药物安全评价研究有限公司
1.遗传毒性试验（Ames、微核、染色体畸变）
药物GLP认证目录
机 构 名 称
试 验 项 目
认证批件编号
湖南普瑞玛药物研究中心有限公司
1.单次和多次给药毒性试验（啮齿类）
2.单次和多次给药毒性试验（非啮齿类）
3.生殖毒性试验（I段、II段、Ш段）
4.遗传毒性试验（Ames、微核、染色体畸变）
5.局部毒性试验
6.免疫原性试验
安全性药理试验
8.毒代动力学试验
生殖毒性试验（Ш段）
GLP21017136
益诺思生物技术南通有限公司
1.致癌试验
2.免疫原性试验
GLP21020139
上海益诺思生物技术股份有限公司
依赖性试验
GLP22001140
江苏鼎泰药物研究股份有限公司
生殖毒性试验（Ш段）
GLP22002141
1.单次和多次给药毒性试验（非啮齿类）
2.免疫原性试验
3.安全性药理试验
4.依赖性试验
GLP21015134
广州博济医药生物技术股份有限公司
（药物评价中心）
1.单次和多次给药毒性试验（非啮齿类，灵长类）
2.生殖毒性试验（I段、II段）
3.免疫原性试验
GLP21016135
山东省医学科学院药物研究所
（山东省医学科学院药物安全评价中心）
AZ960-SDS-MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Oct.-03-2018Print Date:Oct.-03-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :AZ960Catalog No. :HY-10411CAS No. :905586-69-81.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureGHS Classification in accordance with 29 CFR 1910 (OSHA HCS)Acute toxicity, Oral (Category 4),H302Acute aquatic toxicity (Category 1),H400Chronic aquatic toxicity (Category 1),H4102.2 GHS Label elements, including precautionary statementsPictogramSignal word WarningHazard statement(s)H302 Harmful if swallowed.H410 Very toxic to aquatic life with long lasting effects.Precautionary statement(s)P264 Wash skin thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P273 Avoid release to the environment.P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor ⁄ physician if you feel unwell.P330 Rinse mouth.P391 Collect spillage.P501 Dispose of contents ⁄ container to an approved waste disposal plant.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:AZ-960;AZ 960Formula:C18H16F2N6Molecular Weight:354.36CAS No. :905586-69-84. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance Light yellow to yellow (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGUN number: 3077Class: 9Packing group: IIIEMS-No: F-A, S-FProper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.Marine pollutant: Marine pollutantIATAUN number: 3077Class: 9Packing group: IIIProper shipping name: Environmentally hazardous substance, solid, n.o.s.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。