药学英语 标准试卷9

一、翻译（共20分,每题1分）。

1 Nonane2 Sodium3 Silver4 Arginine5 Histidine6 Phenol7 Acetone 8 Sodium chloride9 Potassium carbonate 10 Chlorine11 乙烷12 甲醇13 溴14 汞15 腺嘌呤16 赖氨酸17 胞嘧啶18 乙酸乙酯19 氢氧化钠20 碳酸钾答案:1 壬烷2 钠3 银4 精氨酸5 组氨酸6 酚7 酮8 氯化钠9 碳酸钾10 氯11 Ethane 12 Methanol13 Bromine 14 Mercury15 Adenine 16 Lysine17 Cytosine 18 Ethyl acetate19 Sodium hydroxide 20 Potassium carbonate二、写出下列缩写的英文全称并翻译（共10分,每题2分）。

1 WHO:2 SFDA:3 IR:4 CTO:5 NMR:答案: 1 W orld Health Organization 世界卫生组织试卷（A）共（6）页第（ 1 ）页2 State Food and Drug Administration 国家食品药品监督管理局3 Infrared spectroscopy 红外光谱4 Chief Technology Officer 首席技术官5 Nuclear Magnetic Resonance Spectroscopy 核磁共振光谱三、判断，并用×√表示（共16分,每题2分）。

1 （）There are three phases in the analysis: the fast-screening phase, the identification phase and possible quantification.2 （）The present trend is mass screening of huge libraries containing several thousand molecules. This was made possible by the association of combinational chemistry with NMR.3 （）Presently, as NMR, it is applied in a very general manner to synthetic as well as to natural compounds in the search for new lead compound.4 （）Thus were produced, over millions of years, the earth itself and the chemical elements found on the earth today.5 （）This is determined mainly by the lipid solubility of the drug, highly polar water-soluble drugs being transferred slowly whereas highly lipidsoluble, non-polar drugs are transferred rapidly across the lipid-rich membranes of cells.6 （）Higher concentration of surfactants tends to form micelles with the drug and thus decrease the dissolution rate.7 （）For growth regulators a bioassay is not an essential part of identification.8 （）GMP is probably the most widespread quality system followed across the pharmaceutical industry as a whole答案: 1 √ 2 × 3 × 4 × 5 √ 6 ×7 ×8 √四、单选题（共14分,每题2分）。

1 Analytical chemistry provides the B and tools needed for insight into our试卷（A）共（6）页第（ 2 ）页material worldA choicesB methodsC improvementsD arrangements2 The crucial property for the D was that it should be recognized and bound to the binding site of the target receptor.A chemical messengerB tissueC cellD lead compound3 Aldehydes and ketones have C groupsA acetylB aldehydeC carbonylD carboxyl4 In view of the complexity of the human body, it is inevitable that pharmacokinetic formulations must be A drastically simplifying assumptions.A based onB depend onC come onD according to5 A increase the viscosity of the drug vehicle and thereby diminish the rate of drug dissolution of suspensions.A Suspending agentsB LubricantsC SurfactantsD Excipients6 With new compounds, however, it is A to confirm the identification through chemical degradation or by preparing the compound by laboratory synthesis.A preferableB goodC wellD better7 Low concentrations of surfactants lower _______ and increase _______, whereas higher concentration of surfactants tends to form micelles with the drug and thus decrease _______.A the surface tension the rate of the drug dissolution the dissolution rateB the dissolution rate the surface tension the rate of the drug dissolutionC the rate of the drug dissolution the dissolution rate the surface tensionD the dissolution rate the rate of the drug dissolution the surface tension答案: 1 B 2 D 3 C 4 A 5 A 6 A 7 A五、英译汉（共20分,每题5分）。

试卷（A）共（6）页第（ 3 ）页1 In order to design a drug product that deliver the active drug in the most bioavailable form, the pharmacist must consider (1) the type of drug product (e.g. solution, suspension, suppository); (2) the nature of the excipients in the drug products; (3) the physicochemical properties of the drug molecule.答案：为了设计一种使活性药物最有效的药物产品，药剂师必须考虑到 1 药品的剂型（例如，溶液剂、悬浮剂、栓剂）2 药品中辅料的性质 3 药物分子的物理化学性质。

2 With new compounds, however, it is preferable to confirm the identification through chemical degradation or by preparing the compound by laboratory synthesis.答案：然而对于新的化合物，最好是通过化学降解确认或准备通过实验室合成的化合物。

3 Lead compounds can be obtained from a variety of different sources such as the flora and fauna of the natural world, or synthetic compounds made in the laboratory. There is also the potential of designing lead compounds using computer modeling or NMR spectroscopic studies.答案：先导化合物的来源多种多样，例如自然界中的植物动物或是实验室中的合成化合物，也可以来源于电脑模拟或核磁图谱。

4 Presently, as high-throughput screening (HTS),it is applied in a very general manner to synthetic as well as to natural compounds in the search for new lead compound.答案：现在，高通筛选是适用于合成和天然化合物的一般方法。