habitual abortion

(1)Maternal-fetal recognazation is too low
Blocking antibodies deficiency
(2)Maternal-fetal recognization is too high
Autoimmune abnormal
Immune abnormal
(2)Endocrine disorders
• Luteal insufficiency • Hyperthyroidism or Hypothyroidism • Diabetes
Pituitary →
Hormone 1
Hypothalamus → Ovary
Hormone 2
• Examnations
occurs at about the same stage of pregnancy
Source: www.baidu.com
Causes of habitual abortion:
• 1: chromosome disease • 2:Reproductive factors
• 3:Immune factors
Trisome syndrome(三体综合征):
Source: www.google.cn
18th trisome syndrome
germ cells’ maiosis ’s abnormity
Germ cells
or cytula’s early cleavage’s abnormaity
Trisome
(3)Maternal-fetal recognization is disordered
Behaved on the one hand for blocking antibodies deficiency, on the other hand for abnormal increasing of immune injury.
tend to abort
Abnormal cytula(受精卵）
Our suggestion
do the prenatal diagnosis(产前诊断)
Source: http://image.baidu.com/i?ct=50331B2%FA%C7%B0%D5%EF%B6%CF.
2.Reproductive factors
Source: http://www.sohospital.cn/images/f_98371_1.jpg
Examnations
{
B-type ultrasonography Hysteroscopy(宫腔镜)
Treatment
Surgery →to remove the myoma medicine →to recuperate uterus
Treatment:
Immunotherapy
Thank you !
Uterine facters
Endocrine disorders
{
(1)Uterine factors
Abnormal structure
uterus bicornis , Uterine myoma（子宫肌瘤）
Uterine dysplasiaห้องสมุดไป่ตู้
Multiple miscarriages Uterine injury
1. Chromosome disease
Definition: Abnormity of the structure or
the quantity of the chromosome
Incidence: In habitual abortion, 50%
fetuses have chromosome disease.
Luteal function tests Thyroid function tests Blood glucose
• Treatment
medicine →to get normal hormone levels
3.Immune factors
• Maternal-fetal recognazation is too low • Maternal-fetal recognization is too high • Maternal-fetal recognization is disordered
Habitual Abortion
Group members： Yin Xiaofeng 、Wang Shengnan、
Huang Wenbin、 Xu Yinjuan、 Pu Ruiyang、Zhang Yingxun
Habitual abortion（习惯性流产）：
Three or more times consecutive and spontaneous