外文翻译----数字图像处理和模式识别技术关于检测癌症的应用

引言英文文献原文Digital image processing and pattern recognition techniques for the detection of cancerCancer is the second leading cause of death for both men and women in the world , and is expected to become the leading cause of death in the next few decades . In recent years , cancer detection has become a significant area of research activities in the image processing and pattern recognition community .Medical imaging technologies have already made a great impact on our capabilities of detecting cancer early and diagnosing the disease more accurately . In order to further improve the efficiency and veracity of diagnoses and treatment , image processing and pattern recognition techniques have been widely applied to analysis and recognition of cancer , evaluation of the effectiveness of treatment , and prediction of the development of cancer . The aim of this special issue is to bring together researchers working on image processing and pattern recognition techniques for the detection and assessment of cancer , and to promote research in image processing and pattern recognition for oncology . A number of papers were submitted to this special issue and each was peer-reviewed by at least three experts in the field . From these submitted papers , 17were finally selected for inclusion in this special issue . These selected papers cover a broad range of topics that are representative of the state-of-the-art in computer-aided detection or diagnosis(CAD)of cancer . They cover several imaging modalities(such as CT , MRI , and mammography) and different types of cancer (including breast cancer , skin cancer , etc.) , which we summarize below .Skin cancer is the most prevalent among all types of cancers . Three papers in this special issue deal with skin cancer . Y uan et al. propose a skin lesion segmentation method. The method is based on region fusion and narrow-band energy graph partitioning . The method can deal with challenging situations with skin lesions , such as topological changes , weak or false edges , and asymmetry . T ang proposes a snake-based approach using multi-direction gradient vector flow (GVF) for the segmentation of skin cancer images . A new anisotropic diffusion filter is developed as a preprocessing step . After the noise is removed , the image is segmented using a GVF1snake . The proposed method is robust to noise and can correctly trace the boundary of the skin cancer even if there are other objects near the skin cancer region . Serrano et al. present a method based on Markov random fields (MRF) to detect different patterns in dermoscopic images . Different from previous approaches on automatic dermatological image classification with the ABCD rule (Asymmetry , Border irregularity , Color variegation , and Diameter greater than 6mm or growing) , this paper follows a new trend to look for specific patterns in lesions which could lead physicians to a clinical assessment.Breast cancer is the most frequently diagnosed cancer other than skin cancer and a leading cause of cancer deaths in women in developed countries . In recent years , CAD schemes have been developed as a potentially efficacious solution to improving radiologists’diagnostic accuracy in breast cancer screening and diagnosis . The predominant approach of CAD in breast cancer and medical imaging in general is to use automated image analysis to serve as a “second reader”, with the aim of improving radiologists’diagnostic performance . Thanks to intense research and development efforts , CAD schemes have now been introduces in screening mammography , and clinical studies have shown that such schemes can result in higher sensitivity at the cost of a small increase in recall rate . In this issue , we have three papers in the area of CAD for breast cancer . Wei et al. propose an image-retrieval based approach to CAD , in which retrieved images similar to that being evaluated (called the query image) are used to support a CAD classifier , yielding an improved measure of malignancy . This involves searching a large database for the images that are most similar to the query image , based on features that are automatically extracted from the images . Dominguez et al. investigate the use of image features characterizing the boundary contours of mass lesions in mammograms for classification of benign vs. Malignant masses . They study and evaluate the impact of these features on diagnostic accuracy with several different classifier designs when the lesion contours are extracted using two different automatic segmentation techniques . Schaefer et al. study the use of thermal imaging for breast cancer detection . In their scheme , statistical features are extracted from thermograms to quantify bilateral differences between left and right breast regions , which are used subsequently as input to a fuzzy-rule-based classification system for diagnosis.Colon cancer is the third most common cancer in men and women , and also the third mostcommon cause of cancer-related death in the USA . Y ao et al. propose a novel technique to detect colonic polyps using CT Colonography . They use ideas from geographic information systems to employ topographical height maps , which mimic the procedure used by radiologists for the detection of polyps . The technique can also be used to measure consistently the size of polyps . Hafner et al. present a technique to classify and assess colonic polyps , which are precursors of colorectal cancer . The classification is performed based on the pit-pattern in zoom-endoscopy images . They propose a novel color waveler cross co-occurence matrix which employs the wavelet transform to extract texture features from color channels.Lung cancer occurs most commonly between the ages of 45 and 70 years , and has one of the worse survival rates of all the types of cancer . Two papers are included in this special issue on lung cancer research . Pattichis et al. evaluate new mathematical models that are based on statistics , logic functions , and several statistical classifiers to analyze reader performance in grading chest radiographs for pneumoconiosis . The technique can be potentially applied to the detection of nodules related to early stages of lung cancer . El-Baz et al. focus on the early diagnosis of pulmonary nodules that may lead to lung cancer . Their methods monitor the development of lung nodules in successive low-dose chest CT scans . They propose a new two-step registration method to align globally and locally two detected nodules . Experments on a relatively large data set demonstrate that the proposed registration method contributes to precise identification and diagnosis of nodule development .It is estimated that almost a quarter of a million people in the USA are living with kidney cancer and that the number increases by 51000 every year . Linguraru et al. propose a computer-assisted radiology tool to assess renal tumors in contrast-enhanced CT for the management of tumor diagnosis and response to treatment . The tool accurately segments , measures , and characterizes renal tumors, and has been adopted in clinical practice . V alidation against manual tools shows high correlation .Neuroblastoma is a cancer of the sympathetic nervous system and one of the most malignant diseases affecting children . Two papers in this field are included in this special issue . Sertel et al. present techniques for classification of the degree of Schwannian stromal development as either stroma-rich or stroma-poor , which is a critical decision factor affecting theprognosis . The classification is based on texture features extracted using co-occurrence statistics and local binary patterns . Their work is useful in helping pathologists in the decision-making process . Kong et al. propose image processing and pattern recognition techniques to classify the grade of neuroblastic differentiation on whole-slide histology images . The presented technique is promising to facilitate grading of whole-slide images of neuroblastoma biopsies with high throughput .This special issue also includes papers which are not derectly focused on the detection or diagnosis of a specific type of cancer but deal with the development of techniques applicable to cancer detection . T a et al. propose a framework of graph-based tools for the segmentation of microscopic cellular images . Based on the framework , automatic or interactive segmentation schemes are developed for color cytological and histological images . T osun et al. propose an object-oriented segmentation algorithm for biopsy images for the detection of cancer . The proposed algorithm uses a homogeneity measure based on the distribution of the objects to characterize tissue components . Colon biopsy images were used to verify the effectiveness of the method ; the segmentation accuracy was improved as compared to its pixel-based counterpart . Narasimha et al. present a machine-learning tool for automatic texton-based joint classification and segmentation of mitochondria in MNT-1 cells imaged using an ion-abrasion scanning electron microscope . The proposed approach has minimal user intervention and can achieve high classification accuracy . El Naqa et al. investigate intensity-volume histogram metrics as well as shape and texture features extracted from PET images to predict a patient’s response to treatment . Preliminary results suggest that the proposed approach could potentially provide better tools and discriminant power for functional imaging in clinical prognosis.We hope that the collection of the selected papers in this special issue will serve as a basis for inspiring further rigorous research in CAD of various types of cancer . We invite you to explore this special issue and benefit from these papers .On behalf of the Editorial Committee , we take this opportunity to gratefully acknowledge the autors and the reviewers for their diligence in abilding by the editorial timeline . Our thanks also go to the Editors-in-Chief of Pattern Recognition , Dr. Robert S. Ledley and Dr.C.Y. Suen , for their encouragement and support for this special issue .英文文献译文数字图像处理和模式识别技术关于检测癌症的应用世界上癌症是对于人类（不论男人还是女人）生命的第二杀手。