囊泡作为药物载体的研究进展

囊泡作为药物载体的研究进展

赵 静，王仲妮*

（山东师范大学化学化工与材料科学学院，山东 济南 250014）

摘 要： 囊泡有较强的增溶能力，其双层膜具有较好的牢固性和稳定性，作为药物载体给药途径较广，载药稳定性、药物增溶量以及药物生物利用度较高。本文介绍了囊泡作为药物载体的研究现状，包括囊泡形成，膜结构选择和应用，以及囊泡在口服给药、局部给药和体内给药的应用。关键词：囊泡；表面活性剂；药物载体

中图分类号：R944.5 文献标识码：A 文章编号：1672-979X(2010)03-0129-04

收稿日期：2009-12-24

基金项目：山东省自然科学基金（Y2006B29），贵州省教育厅自然科学研究项目[黔教科（2007）016号]作者介绍：赵静（1985-），女，硕士研究生，从事胶体与界面化学研究

*

通讯作者：王仲妮，女，硕士生导师 E-mail: zhongniw@

Progress on V esicle as Drug Carrier

ZHAO Jing, W ANG Zhong-ni

(College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014，

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