Milli-Q Synthesis 超纯水系统 中文使用说明书
超纯水机中文使用手册
MILLIPORESimplicity （185）个人专用超纯水机中文使用手册厦门莱胜科技有限公司2004年5月 V1.0（以英文原版手册为准）第一章：安装拆箱Simplicity TM系统包括（如附图1）：A.纯水主机一套（Simplicity TM），内含3.5公升储水桶一只。
B.英文使用手册一本。
C.排气用（新的Simpak排气用）倒钩式连接头一只D.Simpak纯化管柱一组。
E.储水桶空气过滤器一只。
F.终端过滤器（POU）Simfilter一只。
安装储水桶（如附图2）A．将储水桶装水1.将储水桶上方的安全把手（locking handle）拉起到垂直位置（A）2.以安全把手将储水桶（B）提起3.以逆时针方向旋转1/4圈，打开储水桶上方的盖子（C）4.将储水桶装满经处理过的水（如：蒸馏水、去离子水、R O水或E l i x TM水）后，重新安装回主机，并且确认已将安全把手放回原来的位置（水平位置）B．安装排气过滤器1. 在储水桶盖子内安装储水桶专用的排气过滤器（D）2. 以顺时针方向旋转1/4圈，将盖子关紧安装纯化管柱—Sim P ak（如附图3）1.按住locking tab键（A）向左方打开纯化管柱的locking handle2.将Simplicity TM主机上连接纯化管柱连接头上的2个保护盖（B）拔除3.再将Sim P ak纯化管柱上的2个保护盖（C）拔除，用几滴水润湿管柱接头上的O型圈4.把Sim P ak管柱推入使装载至主机上（D）5.确定纯化管柱的locking handle已卡紧，并就定位（E）。
纯化管柱的locking handle应该很容易扣上。
如果你必须施力才能推紧的话，这表示Sim P ak未完全就位。
Pak排气1.将连接头（如附图1、C）安装至POU（终端取水处）阀上（注：POU阀内含有O型环作为密封用，因此，请勿使用铁弗龙带缠绕在连接头的螺纹上。
）2.在出水口的下方放置容器3.将Simplicity TM给水阀门转钮扳下，打开阀门4.按下OPERATE键，使STANDBY模式切换至OPERATE模式5.当系统做出1-2公升的水后，再将阀门关闭6.若有可能，将系统留在STANDBY模式使经过一整夜的时间。
Milli-Q_Adv超纯水机使用说明书(中文)
Millipore 公司（“Millipore”）担保，若根据适用的说明使用产品，其产品在发运之日起一年内将符合相 应规范的要求。除此之外，MILLIPORE 公司不作其它任何明示或暗示的保证，也不作出针对特定用途的适销 性或适用性保证。除非 Millipore 公司管理人员签署明确的书面协议同意更改，否则本质量保证以及 Millipore 发布的产品目录和产品资料中的 Millipore 产品数据、技术规格和说明均不得更改。与本保证或上述出版物不 符的口头或书面声明均未经过授权，如有此类声明，不得相信其中的内容。
第 2 章 产品信息 ...................................................................................................2
2-1 MILLI-Q® 超纯水系统概述 .....................................................................................................................2 2-2 MILLI-Q 产水规格..................................................................................................................................4 2-3 系统流程图 ...........................................................................................................................................4 2-4 技术规格...............................................................................................................................................7
MilliporeSigma Milli-Q CLX 7000系列连接水纯化系统用户说明书
®7000 SeriesRobust & Reliable Performancefor Maximum Lab ProductivityYour biomedical laboratory is a busy and demanding environment, with clinical analyzers capable of processing several thousand samples per day. As water is the most frequently used fluidic reagent onboard an analyzer, your choice of water purification system is key to smooth and uninterrupted daily lab operations.The water purification solution must reliably provide your clinical analyzer(s) with consistent water quality that meets CLRW standards of the CLSI®. With the high-throughput Milli-Q® CLX 7000 analyzer feed series, your clinical laboratory benefits from a high-performance and economical water purification solution that fulfills its many critical needs:3Simply log into the MyMilli-Q™ web interface todiscover MyMilli-Q™ Remote Care , our online service and monitoring capability designed to support you in maximizing uptime. This unique service gives you and our support teams access to your Milli-Q ® CLX 7000 system and its data, for quick and precise remote diagnostics as well as repairs. Learn more about thisnew service capability on pages 8 and 9 of this brochure. And because every lab situation is different, our Milli-Q ® Services offering can be customized around your needs:• Before installation, a certified Field Service Engineer will analyze your feed water quality to provide the optimal parameter configuration for your system. This maximizes the performance and reliability of your Milli-Q ® CLX 7000 instrument and associated clinical analyzers.• Choose the Milli-Q ® Service Plan that’s right for your lab—from a single annual Preventive Maintenance Visit with replacement of aging parts, to full system coverage. • Online Contract Management lets you moreefficiently track your water system’s service history and easily schedule maintenance visits.• A range of options lets you customize your service solution. Choices include qualification, calibration and verification services, scheduled consumables shipments, and sanitization.Best-in-class Milli-Q ®Services,now supported by MyMilli-Q™ Remote CareBecause the reliability of biomedical laboratories is critical to patients and doctors alike, we offer an unprecedented level of service with the Milli-Q ® CLX 7000 Series.Trust in Pure Experience & ExpertiseWe are a partner you can count on. As one of the top three R&D investors in the Life Science Toolsindustry, we have a long history of strong partnerships with both biomedical laboratories and major clinical analyzer manufacturers. This valuable experience has enabled us to develop our expertise concerning end-user applications, such as biology, biochemistry, microbiology and immunology, and to design top-quality water purification solutions dedicated to feeding clinical analyzers.The Milli-Q ® CLX 7000 Series is manufactured in an ISO ® 9001- and ISO ® 14001-registered site. Additionally, to ensure efficiency and safety ofoperation, systems are CE-, cULus-, and FCC-certified. Furthermore, to reduce environmental impact, the Milli-Q ® CLX 7000 Series follows European Restriction of Hazardous Substances (RoHS) and Waste Electricaland Electronic Equipment (WEEE) directives.Contact your local Merck office for information about the service offer available for your facility, or visit /milli-qservices4® technology purification stepsElix ® module: Our unique technology is based on anion-permeable and cation-permeable membranes and high-quality, ion-exchange resin.Water produced by the Elix ® module enters the reservoir with resistivity greater than 5 MΩ·cm @ 25 °C (typically up to 15 MΩ·cm @ 25 °C).*The Milli-Q ® CLX 7000 Series relies on complementary water purification techniques, including state-of-the-art Elix ® electrodeionization (EDI) technology, to ensure production of consistently high quality water meets CLRW standards – at low and predictable running costs.In the Milli-Q ® CLX 7000 Series, potable tap water is first treated with a Progard ® pack and purified by reverse osmosis (RO) to remove up to 99% of contaminants. The resulting RO permeate water then enters the Elix ®Bacteria and their by-products interfere with chemistry assays and enzyme immunoassays, typically leading to unstable analyzer calibrations, high absorbance of blanks, reference drifts, and errors on mean patient values.In the Milli-Q ® CLX 7000 Series, UV lamp sanitization occurs at three stages:• During water production , a 254 nm bactericidal UV lamp inactivates bacteria.• In the tank , a UV lamp (ASM, Automatic Sanitization Module) regularly irradiates stored water and the tank walls, preventing bacterial growth and the formation of biofilm.* When CO dissolved in feed water is less than 30 ppm.5Optimize water consumption with an environmentally responsible system containing E.R.A.® technologyMilli-RX™ system(1992)Elix system (2003) with RO recovery loop Today’s Mili-Q CLX 7000Series system with E.R.A. technology10000m 900080007000600050004000300020001000WASTE (m )CLRW (m )Over the last 25 years, we have dramatically reduced water purification system water consumption, enabling laboratories to save up toseveral thousand dollars per year on tap water expenses . The graph shows water consumption and the split between CLRW produced and reject water for three of our water purification systems over a seven-year period (production of 1000 L/day of CLRW-quality water, 312 days per year).The Milli-Q ® CLX 7000 Series incorporates our E.R.A.® (Evolutive Reject Adjustment) technology — providing users with even greater savings.With its innovative and efficient reverse osmosis (RO) recovery loop, the Milli-Q ® CLX 7000 Series optimizes water consumption by recycling part of the waterrejected to the drain, thus reducing water waste and also extending RO cartridge and Progard ® pack lifetimes.Furthermore, depending on the feed water qualityanalysis, the Milli-Q ® CLX 7000 Series will calculate the best water recovery and will automatically optimize water consumption by means of motorized valves.No matter what the feed water temperature, inlet pressure, or conductivity may be, E.R.A.®technology’s automated valves ensure that the Milli-Q ® CLX 7000 Series flow rate and water recovery remain constant.* Users no longer need to manually adjust valves to maintain production flow rate and protect RO cartridge lifetime.These latest RO technologies illustrate our dedication to developing environmentally responsible waterpurification solutions to reduce tap water and system consumables use. The solutions reduce maintenance time, as well as the risk of human error — letting users save money on system operation, and also enjoy peace of mind with higher reliability, and optimized water purification system/analyzer uptime.* Please refer to Feed Water Requirements in the Specifications Table.6User-friendly system interface with all relevant information at a glanceWith its large, innovative touchscreen, the system is designed for intuitive operation, with all information available at a glance in a dashboard format. Nine different languages are available for greater convenience. Navigating and interacting with your water purification system has never been easier!... where a wizard will guide you through the maintenance procedure with easy, step-by-step instructions. You don’t need to be an expert to perform regular maintenance on your system!Clear, visible status of all consumables Notification zone for alerts and alarmsLarge display shows water qualities and storage volumeSystem status zone7An easy-to-use,low-maintenance systemA mobile, customizable systemLow maintenance saves time and increases profitability• Robust and patented Elix ® technology ensuresconsistent pure water, as well as low and predictable running costs – regardless of your feed water quality.* No maintenance is required for the Elix ® module.• An ergonomic and patented pack-locking system lets you change packs easily and quickly.• RFID technology prevents insertion of an incorrect purification cartridge in Milli-Q ® CLX 7000 systems, and also ensures automatic traceability of pack use and replacement, saving time for the user.• Automatic self-maintenance functions significantly reduce tap water use and increase cartridge lifetime: –The Progard ® pretreatment pack incorporatesseveral purification media in just one consumable to protect the RO membrane from particles, free chlorine, and scaling. Maintenance is easier and quicker with only one pack to change! –The system’s flush mode and cleaning cycles keep the RO membrane in top operating condition.Never before has it been so easy—or so time-saving—to use and maintain your water purificationsystem.Optimal use of lab spaceThe Milli-Q ® CLX 7000 Series is compact, quiet, and mounted on wheels with brakes, so it can be placed wherever it’s convenient — and moved to another location as the lab configuration grows or evolves.Customizable systems to fit your specific requirementsA number of options and accessories are available for the Milli-Q ® CLX 7000 Series to fit your specific requirements and to improve water quality monitoring:• An online TOC (Total OrganicCarbon) monitor allows verification that the TOC level of system water is below 500 ppb as required for CLRW quality. This avoids the need for duplicate assays or repeated analyzer calibrations. • Degassing option provides asolution for feed water that is highly contaminated with gases, such as a CO 2 concentration above 30 ppm.• RO regeneration tool , for use whenfeed water quality is poor, provides additional RO membrane cleaning, and completes the action of the Progard ® Autoclean pack.• Sanitary sampling valve for safe and reliable water sampling for microbiological analysis.• Water sensor(s) and alarm output(s) also can be easily added to your Milli-Q ®CLX 7000 system.* P lease refer to Feed Water Requirements in the Specifications Table.An ergonomic and patented pack-locking system.245 13 67What can MyMilli-Q™ Remote Care help you to achieve?• Assure productivity 24/7. Access real-time system information, water quality data and much more from anywhere at any time for 24/7 confidence in your lab’s performance.• Save time. In the event you need support, your interaction with Milli-Q® Services is streamlinedas MyMilli-Q™ Remote Care provides our service organization a secure and direct view of your system information. Our service teams can remotely diagnose and potentially repair your system, avoiding the need to wait for a service visit.• Maximize uptime. Receive notification of alertsand alarms (by email or SMS) allowing you to promptly and remotely manage your system, either independently or with our remote assistance.• Easier data traceability & accreditation. Audit preparation and lab accreditation have never been so effortless as data are automatically saved and can be easily accessed, searched and retrieved. Choose to download a standard Quality Report, or to create your own tailored reports.Connect to Peace of Mind Milli-Q® Services presents MyMilli-Q™ Remote Care, an onlineservice that simplifies the management of your Milli-Q® CLX7000 water purification system.1 Quickly view all system details.2E asily share water quality and system information with your analyzer supplier’sservice hotline.† CAP , College of American Pathologists9A water purification system that facilitates accreditation.Water used to feed an analyzer is a critical reagent. Its quality must be documented forbiomedical laboratories seeking accreditation (or reaccreditation) to the ISO 15189:2012 standard supported by CAP † 15189SM accreditation.To facilitate compliance with worldwide regulatory organization guidelines, Milli-Q ® CLX 7000 systems allow for full monitoring capabilities as well as automatic e-record archiving both:• Directly in the system — data are retrievable by USB key or via your lab’s intranet connection.• In the cloud when MyMilli-Q™ Remote Care is activated.E-record archiving supports traceability of all water-related daily operations, measurements and events. It saves time and is less expensive to manage versus paper documentation, as it removes the need for daily checks of the water purification system, hand-recording of parameters in a lab book, and physically archiving years of paper data.Now, with the user-friendly MyMilli-Q™ web interface and MyMilli-Q™ Remote Care service capability, data management is even moresimplified. Your system and water data are readily accessible and rapidly searchable, graphable and reportable — from anywhere at any time.An interactive Event Traceability tool lets you view events by type and over the timeline you specify. View past events (alarms, alerts, consumable replacements, service visits, custom events) and plan for future systemmaintenance. Click on any event and its details are displayed in the blue banner above the timeline. In this example, aProgard ® cartridge was replacedby J.SMITH on Aug 19, 2019.Water quality parameters (resistivity, temperature, TOC) are graphed over the timeline of your choice and can be easily downloaded.The system automatically stores a fully traceable—and easily retrievable—record of service history. In addition to archiving data, MyMilli-Q™ online tool lets you streamline contract management. You’ll be able to schedule maintenance visits, manage consumable deliveries and renew your service contracts, all online.Milli-Q® CLX 7000 Series Water Purification Process1. Inlet Valve2. Progard® Pretreatment Pack3. Conductivity Cell4. RO Pump5. Pressure Sensor6. RO Cartridge7. Twin Motorized Valve –RO Recirculation 8. RO Recirculation Loop9. Temperature Sensor10. Flow Sensor11. 3-Way AutomaticRinsing Valve12. Elix® Module13. Resistivity Cell14. UV Lamp (254 nm)15. Vent Filter16. Sanitary Overflow Sensor17. Automatic SanitizationModule (ASM)18. Distribution Pump19. Emergency Back Up –Quick Connector20. Q-Gard® Polishing Pack21. Opticap® Filter (0.22 μm)22. Sampling Valve23. Automatic Loop Rinsing Valve24. Back Pressure Regulator25. Recirculation Loop Valve26. TOC Monitor (Option)27. Degassing Unit (Option)Milli-Q® CLX 7000 Series SpecificationsThe Clinical Laboratory Reagent Water (CLRW) Quality Standard, defined by the CLSI®Resistivity> 10 MΩ.cm @ 25 °C Total organic carbon (TOC)< 500 ppbBacteria< 10 CFU/mL Filtration0.22 μmMilli-Q® CLX 7000 Series PerformanceMilli-Q® CLX 7040Milli-Q® CLX 7080Milli-Q® CLX 7120Milli-Q® CLX 7150 Make-up flow rate to reservoir*40 L/h (10.6 gal/h)80 L/h (21.1 gal/h)120 L/h (31.7 gal/h)150 L/h (39.6 gal/h) Make-up resistivity> 5 MΩ.cm @ 25 °C (10-15 MΩ.cm @ 25 °C typically)Built-in reservoir volume (net volume)90 L90 L140 L140 LDistribution flow rate to analyzers 4 L/minDistribution pressure to analyzers Adjustable: 0.9 up to 2.1 bar†Water Quality Distributed to AnalyzersResistivity> 15 MΩ.cm @ 25 °C Total organic carbon (TOC)Typically < 30 ppb Bacteria Typically < 1 CFU/mL Dissolved silica< 0.05 mg/L* Nominal flow rates ± 10% between 10 and 35 °C. Additional deviation of -3% per °C from 10 °C to 5 °C.† With a distribution loop length of 20 m.Technical Appendix10*Subject to subscription. Please contact your local Merck office for information about the service offer available for your facility.Dimensions and WeightsDimensions (H x W x D)1255 x 543 x 797 mm(49.4 x 21.4 x 31.4 in)1255 x 543 x 797 mm(49.4 x 21.4 x 31.4 in)1255 x 543 x 947 mm(49.4 x 21.4 x 37.3 in)1255 x 543 x 947 mm(49.4 x 21.4 x 37.3 in)Net weight (shipping box)134 kg (295.4 lb)143 kg (315.3 lb)155 kg (341.7 lb)167 kg (368.2 lb) Operating weight222 kg (489.4 lb)234 kg (515.9 lb)303 kg (668 lb)318 kg (701.1 lb)Feed Water RequirementsPressure 2 – 6 barFlow rate> 10 L/min at 2 barTap water connection¾ in. Gaz MFeed water type PotableTemperature 5 – 35 °CConductivity10 – 2000 μS/cm at 25 °C pH 4 – 10Total hardness (as CaCO3)< 300 ppmCO2< 30 ppmSilica< 30 ppmMerck KGaAFrankfurter Strasse 25064293 Darmstadt, Germany /labwater。
超纯水净化系统操作与维护规程
□□ 设备名称：Mini-Q Synethsis 超纯水净化系统（CL22） □□□□□□
操作与维护规程
一、操作规程
1.开机前必须先开水源，调节压力在
2.0bar-6.0bar之间。
2.开Elix主机电源，仪器进入自动工作状态，开始制水。
当储水桶内水满后，显示TANKFULL 99%。
3.开MILLI-Q主机电源，扳出水手柄开关至一档，当电导率达到18.2MΩ.cm时，扳开关至二档，既可制超纯水。
4.Elix主机及MILLI-Q主机电源不关，机器定时对其内部构件进行冲洗，以防止污染物对其造成损害。
5.Elix主机过滤柱为PROGARD，而MILLI-Q主机过滤柱为QGARD。
两种型号过滤柱严禁混用。
LI-Q混合树脂柱的仓门必须卡死，防止制水时树脂柱因水压过大而被冲出。
7.当仪器service灯亮时，需要对仪器进行维护，可根据提示信息具体操作，当alarm灯亮时，需对机器立即进行维修。
8.定期更换仪器外设的自来水过滤装置，以减轻仪器自身过滤柱的消耗。
二、维护规程
1.当液晶显示START AUTO CLEAN时,根据仪器的提示进行操作。
2.当液晶显示EXCHANGE PACK,更换前处理装置，清洗过滤筛
3.当液晶显示CL2 CLEAN, 清洗反渗透筒.
4.当液晶显示PH CLEAN, 反渗透筒的彻底清理。
□□ 文件编号：OG01-CL22-00-2000 □□。
Milli-Q超纯水机使用、清洁及维护操作规程
Milli-Q超纯水机使用、清洁及维护操作规程1目的规范质量控制中心试剂、试药的管理，明确对其的管理和使用。
2范围本规程适用于质量控制中心所用试剂、试药的接收、储存及发放。
3职责3.1质量控制中心检验人员应根据本文件的要求执行。
3.2质量控制中心检验人员对本文件的实施负责。
4内容4.1使用4.1.1模式4.1.1.1待机模式在准备维护Milli-Q系统之前，选择待机模式。
处于待机模式时，不能取水。
处于待机模式时，按下Q-POD取水器开关，使Milli-Q系统减压。
见下图所示。
4.1.1.2就绪模式处于就绪模式时，能从Q-POD取水器中取水。
在大部分时间里，Milli-Q系统都应该处于就绪模式。
无论是在夜间、周末，或是其它未被使用的时间段里，都应该让Milli-Q系统处于就绪模式。
在待机模式下，主显示器和Q-POD取水器显示都如图所示。
4.1.1.3从待机模式切换到就绪模式选择就绪，按下键4.1.1.4 从就绪模式切换到待机模式选择待机，按下键4.1.2 了解Q-POD 取水器显示器和键盘 4.1.2.1 Q-POD 取水器显示器闪烁4.1.2.2Q-POD取水器键盘减少取水量增加取水量开始纯水循环定量取水打印产水水质4.1.3查看操作4.1.4 手动取水4.1.4.1 调整Q-POD 取水器的高度按下此处并保持住，上下移动Q-POD 取水器。
4.1.4.2 使用Q-POD 取水器为了取水，在就绪模式下，按下Q-POD 取水器开关。
O L M HQ-POD取水器内置一个微型开关。
如果您把Q-POD取水器开关按到底后松开，Q-POD 微型开关就处于锁定位置。
当微型开关处于锁定位置时，纯水就会以高流速从Q-POD取水器中持续流出。
再次把Q-POD取水器开关按到底后松开，就能使微型开关解锁。
4.1.5定量取水使用Q-POD取水器能实现定量取水，其定量为0.1L，0.25 L，0.5 L，0.75 L，1 L，1.25 L，1.5 L，1.75 L，2L，3 L，……，60L。
Milli-Q Academic超纯水器使用方法
C、取一新柱，用纯水润湿O形圈，并确认O形圈位于柱孔底部，将新柱推入装好，柱子的标签向下。
D、关好蓝色的门，并确认右侧的两个卡口全部卡好。
（3）Millipak-40的更换
当系统产水量低于0.5L/min时，应更换Millipak-40。
A、拧下旧的Millipak-40。
Milli-Q Academic超纯水器使用方法
1、操作
（1）检查贮水桶内原水（RO水、蒸镏水或去离子水）是否浸没仪器进水管口。
（2）接通主机电源，并打开Milli-Q Academic系统后部的电源开关，显示屏上首先显示仪器型号与序列号后继续显示“PRE OPERATION RECIRCULATION”，仪器自检完后进入“PRE OPERATION”预操作状态。
（3）将水枪扳手扳下，此时可从终端过滤器的出水口采水。
（4）采水完毕，将水枪扳手扳上。
2、注意事项
（1）系统应经常处于待机状态，停机时间不超过1天。
（2）如非同一日采水，系统应于当日第一次采水时弃去前1升水。
（3）系统处于待机状态时不产水，为保持待机期间的水质，系统每隔55分钟会自动循环5分钟，循环时显示屏显示“RECIRCULATION”；系统处在待机状态时，请确保水枪扳手扳上。
B、扳起纯化柱接合器的盖子，将金属锁片向上拨出。
C、将纯化柱小心拨出，取一根新柱子，将柱子的防护塞取下，用干净的水湿润柱口的O型圈。
Milli-Q Academic超纯水器使用方法
D、将柱子的孔对准接合器的金属定位杆，并使定位杆穿过该孔，轻轻提起Q-Gard柱，将柱子下端的挂钩伸入并勾住主机下部的开口，然后将纯化柱完全推入。
E、将金属锁片向下插入金属定位杆末端导引槽内以锁定纯化柱。
Milli-Q超纯水器使用指导
Milli-Q超纯水器使用指导∙机器要求常态为“PRE-OPERATE”状态,并保持24小时通电,需要经常检查供水水箱是否充足∙取水时,首先将取水开关开至“循环”档，待显示屏显示的电阻率达到18.2MΩ·cm时,才能把取水开关打到“产水档位∙超滤柱的消毒清洗 (针对Milli-QB或Milli-QS型号)定期地清洗超滤柱对于保证水质，延长超滤柱使用寿命是很有必要的。
Milli-Q纯水系统会每两星期定期显示有关信息"START SANIT." 以提醒您应清洗超滤柱。
在系统软件中有两种清洗程序.程序:1 (7小时)这是在大多数情况下运用的主要清洗程序。
使用这程序可以从下午下班前开始并利用晚上休息时间进行清洗。
使用程序1的时候,在启动后21分钟后关闭出水阀，此后系统会自动运行直至第二天早上。
程序2:(8小时)此程序有一个较长的浸泡过程，适用于当超滤柱的流量下降或柱已污染时。
此程序必须从早晨开始。
使用程序2时，必须在程序启动后71分钟关闭出水阀。
此后，系统会自动运行。
开始清洗时必须准备~30升的进水。
清洗操作步骤如下：按操作/待机“OPERATE/STANDBY” 键2 秒钟,使Milli-Q系统处于待机“STANDBY” 状态。
把MILLIPAK 40/20从出水枪上取下将过渡接头拧在出水口上。
将12mm外径的管子接在过渡接头上，管子的另一端通下水道或水槽。
将取水枪扳手扳下，待出水口无水流出(卸压)，再将扳手扳上。
取下清洗口的盖子，把它放在附近，把3克NaOH(A.R.分析纯)(代替消毒氯片ZWCL01F50)放入清洗口。
将清洗口的“S”形盖子旋回原处，确保没有渗漏。
按控制面板清洗“CLEANING”键2 秒钟。
(若要选择程序2，再按一次清洗键)等待10秒钟后选择被确认，显示屏会显示“SAN.CYCLE 1”将取水枪扳手扳下，系统就开始进入清洗程序。
400分钟后将扳手扳回到朝上的位置注:若出水阀未关，系统不会计时清洗时间.清洗结束后，系统自动回到预操作（PRE OPERATE）状态去掉12mm管子和过渡接头，装好MILLIPAK 40/20.Milli-Q超纯水系统又可以正常使用了。
Milli-Q_Adv超纯水机使用说明书(中文)
目录
第 1 章 引言 .........................................................................................................1
1-1 本用户手册的目的 ................................................................................................................................1 1-2 关于 MILLIPORE .....................................................................................................................................1
如果出现违反上述担保的情况，在客户及时通知的条件下，Millipore 公司的唯一责任就是选择对相关产品 或零件进行维修或更换。如果经过适当的努力后，Millipore 公司无法修复或更换产品或零件，则 Millipore 公 司应退还客户购买此产品或零件的全部费用。对于客户因使用产品而遭受的间接损失、附带损失、特殊损失或 其它由于经济或财产损失导致的间接损失，Millipore 公司不承担责任。
Millipore 的标准质保声明
Millipore 公司（“Millipore”）担保，若根据适用的说明使用产品，其产品在发运之日起一年内将符合相 应规范的要求。除此之外，MILLIPORE 公司不作其它任何明示或暗示的保证，也不作出针对特定用途的适销 性或适用性保证。除非 Millipore 公司管理人员签署明确的书面协议同意更改，否则本质量保证以及 Millipore 发布的产品目录和产品资料中的 Millipore 产品数据、技术规格和说明均不得更改。与本保证或上述出版物不 符的口头或书面声明均未经过授权，如有此类声明，不得相信其中的内容。
超纯水设备说明书
更换Progard 预处理柱
更换Millipak 终端精制器
○ 您可以在5分钟内完成Progard预 处理柱或Q-Pak精纯化柱的更换。
○ 设备上的RFID电子识别标签，可 自动在系统存储器中对耗材进行 识别和登记，让您快速轻松地进 行追溯。
○ 需要维护时，系统会至少提前15天 提醒您更换耗材或预约服务拜访， 确保您用水不会中断。
Milli-Q® Direct水纯化系统
从自来水直接生产纯水/超纯水的一体化系统
高性价比的一体化系统为您带来 一机两水的极致体验
科研用户更高的需求:
价格适当且能够直接从自来水制备纯 水和超纯水的系统：
- 符合不断提高的水质标准 - 方便易用 - 节约实验室空间 - 实现低运行成本
Milli-Q Direct解决方案：
Q-Pak®精纯化柱生产的超纯水 适用于大多数的应用-带有RFID 标签确保安全性&可追溯性
位于左侧门内的“快速参考指 南”可提供所有必要信息
菜单式设计，系统信息一览无遗
○ 简化详尽的信息提供(中文支持)。 ○ 提示&报警(可通过蜂鸣报警器加强提醒)信息可清晰地显示在系统的
主显示屏上，并可通过手动操作获得完整信息。 ○ 传感器定期检测系统运转，确保系统在规格要求的范围内运转。例
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Milli-Q Direct 8 ˞ Milli-Q Direct 16˞ Ᏹ Progard T3ጥӐಎ Q-Pak TIXጥӐಎ Q-Pak TEXጥӐಎ Millipak Express 40໙٧ (0.22 μm) BioPak ໙٧ EDS-Pak ໙٧ LC-Pak ໙٧ VOC-Pak ໙٧ ᬃ͇ Q-POD ᡓጥපԨප٧(Ԩපᒥ) POD ેܖጷ͇ ˞ેܖጷ͇ ᑭᢅԨපधС ප٧ 254 nm ጋܰ༤ӣጞጷ͇
Milli_PORE超纯水机使用说明书
1/ml (顆粒大小> 0.22m)
熱源
< 0.001 Eu/ml
總有機碳
小於5 ppb (此規格由下列條件進行測試所得之結果: Milli-Q Synthesis安裝Q-Gard1純化管匣及QuantumEX精製管匣,進水則由Millipore RiOs逆滲透純水系統所供應。其TOC值< 50 ppb)。當進水之TOC值若小於50 ppb時Milli-Q的產水TOC值便可達到此規格
EDI
電子式連續再生去離子模組(參考Elix系統)
Eu/ml
每毫升中所含之內毒素單位(內毒素濃度)
LCD
液晶螢幕
LED
發光二極體
LPM
公升/分鐘(流速)
M.cm
百萬歐姆•公分(比阻抗值之單位)
M.cm @ 25C
補償至25C的比阻抗值
mm
毫米
NPT
公制管牙(管接頭之牙口型式)
NPTF
公制內管牙
NPTM
Tel. (01) 908-30-60
Fax (01) 908-30-80
Lausanne:
Tel. (021) 641 2550
Fax (021) 641 2551
TAIWAN
Taipei:
Tel. (886-2) 2792-9333
Fax (886-2) 2792-6555
U.K.
Tel. 01923 816375
Milli-Q系統上共有四個按鍵分別為:OPERATE/STANDBY, MEASURE, CLEANING及MENU。
液晶螢幕為背光式雙列16字元LCD顯示幕
LED指示燈則位於LCD之右邊的位置。POWER LED「電源指示燈」為綠色。當系統開機之後此燈便會持續亮著表示微處理器有電源供應。SERVICE LED「維護保養指示燈」為黃色。當系統有需要進行維護保養之事項時LCD會出現訊息要求使用者進行處理同時SERVICE LED會配合閃爍,例如:當LCD出現”EXCH. CARTRIDGES”時表示純化管匣必須更換。ALARM LED「警報指示燈」為紅色。當系統出現異常之警報事項時LCD會出現警報訊息,要求使用者進行處理同時ALARM LED會配合閃爍,例如:當LCD出現”PAK NOT IN PLACE”,表示純化管匣未安裝於正確位置，導致系統出現警報情況。
Milli-Q_Synthesis_超纯水系统_中文使用说明书
Milli-Q Synthesis 超纯水系统中文使用说明书Milli-Q Synthesis超强组合型详细说明：IVF等极为困难的特殊培养以及分子生物学实验专用Milli-Q Synthesis系结合Gradient所采用的短波UV灯(185nm)以及Biocel所采用的5,000分子量的UF 膜，其产水的TOC值可在5ppb以下(当进水的TOC值低于50ppb)，热源则低于0.001EU/ml的新型超纯水装置。
本系统特别适用在容易受到水质影响的IVF或是DNA、RNA等分子生物学实验。
当然，Milli-Q Synthesis 的产水也可使用在需高灵敏度的HPLC检测上。
功能◆TOC数值显示◆电阻率显示◆水温显示◆纯水柱更换显示◆“A10”UV灯更换显示◆UV灯更换提示◆UF膜自动清洗◆消毒提醒◆定期循环◆定量取水◆取水纯度设定◆运转状态输出需加装“A10”TOC检测仪技术指标产水量 1.5L/min电阻率18.2MΩ·cm(25℃)总有机碳TOC 〈5ppb热源0.001EU/mL细菌〈1cfu/mL颗粒〉0.22um 〈1P/mLElix产水作为进水，其TOC值低于50ppbMillipore公司是驰名世界的纯水及超纯水设备制造商，根据用户的独特要求设计制造出一系列不同的纯水及超纯水系统。
其中Milli-Q系列更是所有从事化学分析、生化研究及细胞培养所不可缺少的，该系统以反渗透水、蒸馏水、Elix水或去离子水为进水，随时提供符合美国材料试验学会(ASTM)、美国病理学会(CAP)和临床医学会(NCCLS)规定的I级(试剂级)超纯水。
a)纯化系统将自来水作初步处理，一般包括预过滤（深层过滤及膜过滤）和反渗透或蒸馏法，而反渗透因其污染物去除率达到90%-95%以上，回收率达20%-40%以上，效益比传统纯蒸馏法更理想，因此是Milli-Q超纯水系统的理想进水。
另外，Millipore为配合日渐普及的微量分析，研制出Elix连续电流去离子系统，结合反渗透及连续电流去离子技术的优点——经济高效(R〉5MΩ·cm)，可用于一般实验室作分析用水，又因其出水质量高，如作为Milli-Q的进水，更能提高Milli-Q纯化柱的使用寿命及出水水质。
MilliQ超纯水机使用、清洁及维护操作规程
Milli-Q超纯水机使用、清洁及维护操作规程————————————————————————————————作者：————————————————————————————————日期：Milli-Q超纯水机使用、清洁及维护操作规程起草人部门：质管部签名/日期：审核人部门：质管部冯汇签名/日期：部门：生产部董亚博签名/日期：部门：综合管理部张文忠签名/日期：部门：陈华签名/日期：批准人赵健签名/日期：分发范围部门：质管部数量：1份部门：生产部数量：—部门：综合管理部数量：—部门：新品部数量：1份部门：人力资源部数量：1份部门：财务部数量：—部门：销售部数量：—留档数量：1份1目的规范质量控制中心试剂、试药的管理，明确对其的管理和使用。
2范围本规程适用于质量控制中心所用试剂、试药的接收、储存及发放。
3职责3.1质量控制中心检验人员应根据本文件的要求执行。
3.2质量控制中心检验人员对本文件的实施负责。
4内容4.1使用4.1.1模式4.1.1.1待机模式在准备维护Milli-Q系统之前，选择待机模式。
处于待机模式时，不能取水。
处于待机模式时，按下Q-POD取水器开关，使Milli-Q系统减压。
见下图所示。
4.1.1.2就绪模式处于就绪模式时，能从Q-POD取水器中取水。
在大部分时间里，Milli-Q系统都应该处于就绪模式。
无论是在夜间、周末，或是其它未被使用的时间段里，都应该让Milli-Q系统处于就绪模式。
在待机模式下，主显示器和Q-POD取水器显示都如图所示。
4.1.1.3从待机模式切换到就绪模式选择就绪，按下键4.1.1.4 从就绪模式切换到待机模式选择待机，按下键4.1.2 了解Q-POD 取水器显示器和键盘 4.1.2.1 Q-POD 取水器显示器1待机模式和就绪模式机模式被用于维护、设定、或进入管理员菜单。
就绪模式被用于Milli-Q 超纯水产水。
2水箱液面如果Milli-Q 系统由水箱提供进水，那么其容量由10个条形图代表。
Milli-Q水质仪产品说明书
Data SheetMilli-DI ® SystemAn ideal solution for standardlaboratory needs, providing deionized water directly from your tap waterDispense deionized water easily by simply turning the dispensing valve.As long as the green LED is on, the water quality is above 1 MΩ.cm at 25 °C. When the LED is red, it’s time to change the purification pack (DI-PAK ®).Key Benefits• Compact and easy to use• Battery-powered with no need for electric outlet • Easy maintenance due to purification pack design • Easy control of the water quality • Low investment • Simple installationThe Milli-DI ® system instantly provides pure water directly from your water supply. The system isespecially suitable for standard chemical applications, for the production of buffers and reagents, as well as microbiological culture media. It can also be used as good pretreatment for the Simplicity ® systems. The Milli-DI ® system meets the daily needs of users requiring low volumes of purified water, from 3 to5 liters per day.The life science business of Merck operates as MilliporeSigma in the U.S. and Canada.Easy maintenanceOur DI-PAK ® purification pack is designed to be changed in a matter of seconds with no risk of leakage. The medium sized DI-PAK ® purification pack allows the purification of about 300 liters of water (feedwater conductivity = 400 μS/cm and dissolved CO 2 = 0 ppm)The LED display warns you when pack exchange is needed.Simple installationThe system design allows easy installation in any laboratory. The wall-mounted system is simply connected to the water supply.Installing your Milli-DI ® system will only take you a few minutes:• Connect the adapter to the tubing, and then to the water supply • Connect your system to the tubing• No electric outlet needed (battery-powered)Note: Tubing, fitting, 9-volt battery and tape are accessories provided with your Milli-DI ® system.SpecificationsProduct water quality• Resistivity: > 1 MΩ.cm at 25 °C • Flow rate: 0.5 L/min to 0.7 L/minFeedwater requirements• 14 psi < Feedwater pressure < 70 psi • Potable tap waterFor bacteria-free waterSimply add a 0.22 μm Millipak ® filter at the point of use.Accurate control of water qualityThe resistivity cell has been specifically designed to display a cell constant of 0.14 cm -1 suitable for the measurement of 1 MΩ.cm water quality. In addition, the resistivity meter is temperature-compensated which enables you to use the same temperature reference (25 °C) to check the water quality each day.DimensionsHeight: 430 mm (16.9 in.) Width: 270 mm (10.6 in.) Depth: 170 mm (6.7 in.)Operating weight: 5.6 kg (12 lbs.) Ordering informationMilli-DI ® SystemZFDI00001DI-PAK ®Purification Pack (Medium size: 2.3 L)CPDI0NJM1DI-PAK ® Purification Pack (Large size: 3.2 L)CPDI000L10.22 μm Millipak ® 40 Final Filter MPGL04GK2Milli-DI ® 0.2 µm Filter AdapterMDI02ADAP© 2019 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. Merck, Milli-Q, the Vibrant M, Milli-DI, DI-PAK, Millipak and Simplicity are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.To place an order or receive technical assistanceIn Europe, please call Customer Service:France: 0825 045 645 Germany************ I taly: 848 845 645 Spain: 901 516 645 Option 1 Switzerland: 0848 645 645 UnitedKingdom************For other countries across Europe, p lease call: +44 (0) 115 943 0840 Or visit: /offices For Technical Service visit: /techservice Merck KGaAFrankfurter Strasse 250 64293 Darmstadt, GermanyPF1041EN00 Ver. 2.02016 - 0019310/2019。
Milli-Q Reference 纯水系统说明书
Ultrapure water byMerck MilliporeScientists today face many challenges. As always, they need to deliver high quality technical results. But now, they must do so at a faster pace, while meeting increasing standards and often operating in laboratories with limited space.Merck Millipore designed the Milli-Q® Reference system to address these needs. From pure water, the system produces ultrapure water adapted to your specific applications and exceeding the requirements of the most demanding norms.We’ve achieved all this with a new purification strategy. Water is purified in a first step to reach a resistivity of 18.2 MΩ.cm at 25 °C and a TOC value below 5 ppb. This water is sent through a small recirculation loop to the Application-Pak, where a final purification step, critical for specific experiments, removes contaminants just before water leaves the system.The flow schematic on the next page shows how the water is purified and delivered by the system.Convenience in water deliveryThe Milli-Q® Reference system delivers water the way scientists need it for convenience and time savings, improving laboratory efficiency.Easily prepare solutions with the low flow function to precisely adjust the meniscus in volumetric flasks.The 75 cm long tubing reaches the sink for easy glassware washing.Save time with the volumetric function, automatically deli-vering the water volume that you need, designed to fit the height&shape of all labora-tory glassware.Deliver water hands-free using the footswitch op-tion for more convenience.2Milli-Q® Reference System at a glanceApplication-Pak adapted to specific contaminants removalConsistent delivery of Ultrapure quality water adapted to your needsDispenser on support adapted to glassware height and shape for automatic volume deliveryRange of accessories & optionsQuantum® polishing cartridge adapted to general applicationQ-Gard® pretreatment pack adapted to pure feed water qualityLarge digital & graphic screen with detailed procedures for full on line support34A Quick Reference Guide located in the door of the Milli-Q® Reference water system provides additional support for retrieving information. The system comes with a complete and detailed user manual in 8 languages on CD-ROM. A printedmanual contains essential information (in local language).E asy accEss to informationAccess to water system data is structured simply, so you can save time instead of searching endless numbers for the one you want.The Main Screen on the production unit delivers detailed information in (local language) on system operation and performance. Clear graphics help you perform specific tasks such as maintenance. From the same screen, you can even print reports on the system’s water quality and history.Fields related to critical information such as the definition of water quality set points are accessible only to the designated responsible user and are protected by an identification code and a password.Alerts & alarms are clearly visible on the system’s main screenand can be enhanced by a buzzer.• You can replace the Q-Gard® pretreatment pack or the Quantum® polishing cartridge in less than 5 minutes. These consumables have an RFID tag, automatically registering the catalog and lot number of the new unit in the system’s memory, so that you can quickly and easily maintain traceability.ServiceMerck Millipore provides a comprehensive range of service programs performed by certified Merck Millipore field service support engineers to thoroughly maintain and validate your Milli-Q® system, complying with your industry’s regulatory standards.The service program portfolio covers all maintenance requirements such as installation, customized user training, scientific and technical support, troubleshooting, preventive maintenance visits, and all validation requirements using ad hoc calibrated equipment, procedures,workbooks and suitability tests within a GXPs environment.Q-Gard® Pretreatment PackQuantum®Polishing CartridgeTOTAL WATER SOLUTIONSTo get the best results from your Milli-Q ® Reference system, Merck Millipore recommends feeding it with pure water produced by RiOs™ (Type 3) or Elix® (Type 2) water systems.• The UV lamp built inside the system is designed to last at least 2 years.• The system will alert you to replace consumables or schedule service visits at least 15 days before maintenance is actually required, soyou’ll never be without the water you need.Application-Pak• Replacing the Application-Pak takes less than 2 minutes.Easy and reduced maintenanceMaintaining the Milli-Q® Reference system won’t take time away from your research. Maintenance frequency is minimal, and the procedures are simplified to the utmost.6Feed Water Specifications * For pressure above 0.3 bar, a pressure regulator needs to be installed upstream of the system; for pressures between 0 and -0.2 bar, the system will operate, butproduct flow rate may be lower.Milli-Q® Reference System Dimensions Product Water Quality 1Resistivity can be displayed temperature-compensated at 25 °C or non-temperature-compensated as required by USP 2TOC spec – Test conditions: Milli-Q® Reference system equipped with Q-Gard® T1 pack and Quantum® TEX cartridge, feedwater produced by Elix® system with resistivity > 1 MΩ.cm at 25 °C, TOC < 30 ppb. Product water quality may vary due to local feed water conditions.3Results with Millipak® filter 4Results with Biopak® final polisher in placeThese values (validated with Elix® feed water) are typical and may vary dependingon the nature and concentration of contaminants in the feed water.Q-POD® Accessory Dimensions SafetyThe Milli-Q® Reference system is tested by an independent and accredited company for compliance with the CE directives related to safety and electromagnetic compatibility. The report can be consulted on demand.The Milli-Q® Reference system is built using components and practices recommended by UL and has been cUL marked. The registration can be verified on the UL web site ().CertificationThe Milli-Q® Reference system is delivered with a Certificate of Conformity ensuring that it has been built and tested fully assembled following Merck Millipore Standard Operating Procedures and a Certificate of Calibration for the temperature and resistivity meters built in the system. The Milli-Q® Reference consumables are automatically delivered with a Certificate of Quality.Merck Millipore’s manufacturing site is ISO® 9001 v.2000 and ISO® 140001 certified.A report on conformity of Milli-Q® Reference water quality to Type 1 water quality as described by ASTM®, ISO® 3696 and CLSI® norms and to Purified Water as described in USP and EP is available upon request.Milli-Q® Reference system water specifications7AccessoriesCustomize your Milli-Q® Reference system to meet your specific needs.Space SaversSave your bench space for your crucial experiments by removing the arm and dispenser from the Milli-Q® Reference system and mounting it on the Q-POD® support. Place the water purification cabinet under your bench, or high on a wall, freeing your bench for your research. More space savers include:• Milli-Q® Reference Wall Mounting Bracket • Q-POD® Wall Mounting Bracket• Increase access to water from your bench • Save even more spaceQ-POD® Dispenser: Water delivery at your fingertips The ultrapure water produced in the cabinet is sent in a small recirculation loop to the outlet of the Q-POD® dispenser. Water is delivered from the Q-POD® outletThe Q-POD® dispenser is loaded with convenient features: • Variable water flow (slow flow to 2 L/min) controlled by plunger• H and-held gun dispensing option to facilitate washing applications• Volumetric dispense control with + and – buttons to select dispensed volume• Multicolor graphic display shows at a glance that the water quality is within specification and the system is operating without alarms.• Printer connection to instantly record water quality historySystem ProtectorsSensors can help keep your Milli-Q® Reference system running with minimal vigilance on your part.• Water Sensor – Placed on the floor, this sensor stops water feed to the system if there is water on the floor. No more water spills, even if users forget to stop water delivery while filling containers.• Feed Water Conductivity Meter – If ionic contamination of feed water exceeds specifications, causing high conductivity, an alarm will alert you.• Level Sensor – If your Milli-Q® Reference system is fed from a Merck Millipore tank, this electronic connector transfers tank level information to the Milli-Q® system. The sensor stops water feed from an empty tank and lets you check water levels in the tank before sourcing water, preventing air from entering the system.• Silicone Q-POD® Cover – The Q-POD® dispenser is designed to operate in a wet environment. However, this silicone cover protects your Q-POD® from harsh chemicals, solutions or solvents.FootswitchConnect the footswitch to the base of the Q-POD® dispenser or directly to the Milli-Q® system for hands-free water delivery: pressonce to start and once to stop.Merck Millipore, the M mark, BioPak, Millipak, Milli-Q, Q-POD, Q-Gard, Quantum and Elix are registered trademarks of Merck KGaA, Darmstadt, Germany. RiOs is a trademarks of Merck KGaA.ASTM, ISO, and CLSI are registered trademark of their respective owners.PB0015EN00© 2013 EMD Millipore Corporation, Billerica, MA, U.S.A. All rights reserved.。
MilliporeSigma Milli-Q EQ 7000 超纯水纯化系统说明书
The life science business of Merck operates as MilliporeSigma in the U.S. and Canada.Lab Water SolutionsMilli-Q ® EQ 7000Ultrapure water purification systemThe AuthenticMilli-Q ® Ultrapure ExperienceDesigned for Modern-Day ScientistsScientists Face Many Challenges. Water Should Not Be One of Them.To deliver reliable, high-quality scientific results, you require consistently high-quality ultrapure water.The Milli-Q ® EQ 7000 ultrapure water system is designed to produce consistent ultrapure water quality[resistivity 18.2 MΩ·cm @ 25 °C; total organic carbon (TOC) ≤ 5 ppb] that can be adapted to each user’s specific application requirements. Plus, a range of intelligent design features make it effortless to dispense water as needed and where needed in the lab.An ultrapure water system designed by scientists, for scientists.2* Vs. our previous generation Milli-Q ® Reference system.Convenient Q-POD ® dispensing• 3 flow rates or one-touch volumetric dispensing • Dispenser mounts where you want, up to 3 m from the system • Confidence as you work with ‘Check & Dispense’ lightsFlexibility that adapts to your needs• Multiple space-saving setups: on or under the bench, or on the wall • Customize water quality with application-specific final filters • Hands-free dispensing foot pedal optionControl at your fingertips• Large, intuitive touchscreen simplifies system use and data access • Place the screen where you want, up to 3 m from the systemAt-a-glance quality monitoring• Rapid quality monitoring assures your every dispense • Inline proprietary TOC indicator measures at the point of useCreate a compact & flexible benchtopsetup by systemmounting the Q-POD ® dispenserand placing the screen anywhere on the bench, up to 3m.Save space by placing the system (A) on the wall, or (B) under the bench.Feed pure water from a pressurized loop or storage tank.Flexibility that Fits Your Space & NeedsChoose an installation option that works for you3* Feed water must be pretreated with one of the following purification technologies: Elix ® electrodeionization (EDI), deionization (DI), reverse osmosis (RO), or distillation.Production unit installation options• Benchtop • Under bench • Wall mountedPure water* feed options from a• Distribution loop • Milli-Q ® pure water storage solutionQ-POD ® dispenser options• System mount with choice of positions: on the left or right side, and at the top or bottom of the system or• Wall mount, up to 3 m from the systemHMI touchscreen options• Maintain movement flexibility with a 3 m cable that connects the screen to the main unit; Hold, move and use the touchscreen as is most comfortable for you or• Wall mount, up to 3 m from the systemultrapure water• Wall- or system-mounted setup options (see page 3)• Q-POD ® dispenser rotates on a fixed arm for convenient filling • Unhook the Q-POD ® dispenser from its magnetic hold for agile manipulationConfidenceCheck & Dispense lights on the Q-POD ® arm rapidly confirm that your every dispense is a high-quality dispense.System power Water quality 4…With All Information at Your FingertipsUser-friendlytouchscreen interfaceNavigate and control yourMilli-Q ® EQ 7000 system efficiently and effortlessly with its 7” (~18 cm) colored, touchscreen.Intuitively organized menus help you quickly find what you’re looking for, including:• System information and controls • Water quality monitoring • Dispense options• Purification cartridge status • Data access and reportsAt-a-glancequality monitoringEssential water quality information is conveniently in view on the touchscreen interface:• Resistivity and temperature • TOC indication (see page 7 for more information)• Application POD-Pak installed • Water recirculation statusAfter each dispense, updated resistivity and temperature measurements and the TOC indication are displayed on the screen.Connect to simplified system monitoring & data managementConnect your Milli-Q ® EQ 7000system to an authorized network or device:• Local network (DHCP protocol/fixed IP address) via an Ethernet port• Laptop with a fixed IP addressConnectivity facilitates:• Remote system monitoring and control • Rapid data access• Paperless data managementAlternatively, data can be transferred to a USB key from the port on the touchscreen.Just tap or swipe to control and monitor your system and its data.Intuitively organized system menus support ease of use and greaterlab efficiency.Colored icons display the status of installed purification cartridges.Essential water quality information is in view.A USB port supports easydata export.5Support for Your Sustainability GoalsAt Lab Water Solutions, we are proactively engaged in reducing the environmental impact of our products and supporting your efforts to identify more sustainable solutions. All our products are produced at our ISO 14001 and ISO 50001 certified manufacturing site and all our systems comply with critical environmental regulations and directives, such as RoHS, REACH and WEEE.We are proud of the innovation and design features that give the Milli-Q ® EQ 7000 system a reduced environmental footprint vs. our previous generation Milli-Q ® Reference system:Reduced plastic and size• 20% reduced plastic weight • Up to 25% smaller footprint• 33% smaller and lighter purification cartridges. Smallerbeads of IQnano ® ion-exchange media reduce the bedvolume and improve kinetics within the IPAK Quanta ®and IPAK Meta ® polishing cartridges.• >50% plastic by weight from suppliers following the Together for Sustainability approach, audited by EcoVadis.Reduced electricity consumption• >10% overall energy savings• Lab Close mode saves energy and reduces wear of system components as recirculation is reduced to once a day during long periods of inactivity. The system automatically resumes hourly recirculation 24 hours prior to resuming lab activity, ensuring the system is ready for use.Easy Upkeep & Carefree MaintenanceWe’ve made the Milli-Q ® EQ 7000 system easy to use and carefree to maintain so that your valuable resources can focus on what truly matters – accurate scientific results.• Automated quality upkeep , including a recirculation loop and Lab Close mode, ensure that water quality is preserved when the system is not in use • Automatic alerts notify youwhen purification cartridges need replacing to avoid risk of impacting major components• Coordinated, once-a-yearpurification cartridge replacements minimize hassle • Onscreen wizards guide you to perform simple maintenance and troubleshooting procedures in-house • Twist & Lock cartridgereplacements can be confidently performed by anyone in the lab in a few minutes • Predictableoperating costsTo replace purification cartridges, scan the QR code to be automatically connected to:/mymilliqconsumablesTwist & Lock cartridgedesign makes consumable changes easy and fast.In 2020 and 2021, Merck KGaA, Darmstadt, Germany was awarded Platinumstatus from EcoVadis, placing us in the top 1% of all companies assessed.6Work Confidently with Authentic Milli-Q ® Ultrapure WaterThe Milli-Q ® EQ 7000 system produces ultrapure water that exceeds the requirements of the mostdemanding norms and can be adapted to your specific applications. (See page 10 for details on how water is purified and delivered by the system.)Water quality gradeWith respect to daily, freshly produced water, the Milli-Q ® EQ 7000 system is intended to dispense ultrapure water that meets or exceeds water quality specifications described by the organizations below:OrganizationWater quality/gradeEuropean Pharmacopoeia Purified water in bulk U.S. Pharmacopeia Purified water in bulk Japanese Pharmacopoeia Purified water Chinese Pharmacopoeia Purified water ASTM ® D1193 Type I water ISO 3696Grade 1 water Chinese National Standard GB/T 6682Grade 1 water Chinese National Standard GB/T 33087Ultrapure water JIS K 0557A4 waterClinical and Laboratory Standards Institute (CLSI ®)Clinical Laboratory Reagent Water (CLRW)Rapid, inline Milli-Q ® TOC indicatorTo ensure the reliability of your organic-sensitive applications, such as HPLC, the Milli-Q ® EQ 7000 system integrates a new, proprietary TOC indicator that assures organic contamination is ≤ 5 ppb. This inline indicator provides TOC at the point of use, so you’re certain every dispense is an optimal dispense.ParameterMilli-Q ® TOC IndicatorMonitoring frequency At dispenseAccuracyAccurate indication within the range TOC values display ≤ 5 ppb, if 0–5 ppb ≤ 10 ppb, if 6–10 ppb>10–999 ppb, a whole number is displayed TOC measuring process Inline, post-dispensePhotooxidation UV lampLow pressure mercury lamp, 185 nm UV lamp replacement frequencyOnce every 2 yearsMilli-Q ® TOC IndicatorOnce a dispense is complete, product water flows through the recirculation loop inside the system to the UV oxidation lamp, bypassing theIPAK Meta ® polishing cartridge. UV radiation oxidizes neutral organics into charged molecules, increasing water conductivity. This change is detected by an intermediate resistivity sensor and is converted by an algorithm to a TOC value. The TOC indication appears on the touchscreen monitor after eachdispense.7A Powerful Combination of Purification MediaSlim IPAK Meta ® and IPAK Quanta ® cartridges are designed to function as a pair. The cartridges use acombination of Jetpore ® mixed-bed ion-exchange resin and innovative IQnano ® ion-exchange media to provide exceptional performance. The IQnano ® media’s smaller bead size significantly improves the resin’s kinetic properties. This reduces media needs dramatically: 33% less than former Milli-Q ® cartridges — while still achieving ion removal down to trace level.Other available POD-Paks include: • EDS-Pak ® polisher for endocrine disruptor experiments • LC-Pak ® polisher for trace and ultra-trace organic analyses • VOC-Pak ®polisher for analysis of volatile organic compoundsAll Application POD-Paks feature:• e-Sure tags for full data traceability and consumable status monitoring • Easy snap-into-place installation •Dispensing protective bell8Match Water Quality to Your NeedsApplication POD-Paks are final filters that adapt water quality to specific application needs. Each targets specific contaminants and removes them right at the Q-POD ® dispenser.Millipak ® & sterile Millipak ® Gold 0.22 μm filters to remove bacteria and particulates from water.Biopak ® ultrafiltration polisherfor critical applications requiring pyrogen-, nuclease-, protease- and bacteria-free water.Jetpore IQnanoIPAK MetaIPAK QuantaActivated carbonIQnanoTrust Best-in-Class Milli-Q ® ServicesAnd save time with MyMilli-Q™ digital servicesFrom installation and training to yearly check-ups and our timesaving digital solutions, with Milli-Q ® Services you receive best-in-class service and support from the people who designed and built your system.Quality certified & globally harmonized expertise• Only Milli-Q ®-certified field service engineers install, maintain and repair our systems • Genuine parts from our ISO 9001-certified manufacturing site• In compliance with our worldwide, auditable Standard Operating Procedures • Standardized visit reports and traceable records of careInstallation & user training• Highly trained engineers efficiently install your system, supplying all components required • Receive user training and advice on how to use your systemMilli-Q ® Service Plans & support options to meet any lab’s needsTo ensure your Milli-Q ® system continuously operates at optimum efficiency, we provide a range of service plans and options that can be tailored to suit your application, compliance and budgetary requirements. All Milli-Q ® Service Plans include an annual preventive maintenance visit from one of our engineers and access to our cloud-based digital service portal, MyMilli-Q™ online solution.Milli-Q ® digital servicesLog into MyMilli-Q™ online solution to streamline the care of your Milli-Q ® systems:• Track service history and reports • Manage purification cartridge deliveries • Plan maintenance visits• Renew service contracts and Consumable Supply Agreements ® Services hotline* For the Milli-Q ® EQ 7000 system, applies to temperature and conductivity cells.:/milli-qservices9Customized installationUser trainingVerificationand calibration*Technical AppendixMilli-Q® EQ 7000 ultrapure water systemThe Milli-Q® EQ 7000 system manages the production and the distribution of ultrapure (Type 1) water from a purified water source, such as a PE tank, the Milli-Q® IX/IQ tank, or a pressurized loop.Water is purified to a resistivity of 18.2 MΩ.cm at 25°C and TOC ≤ 5 ppb. During dispense, water is sent through a small recirculation loop to the Q-POD® dispenser where a final purification step—the Application POD-Pak—removes specific contaminants just before water leaves the system.Flow schematic1011Purification unit specificationsCompact benchtop solutionBenchtop HMI touchscreenRemote wall-mounted solutionFront viewTop viewFront viewTop view34.2 cm [13.4 in]19 cm [7.4 in]19 cm [7.4 in]49.8 c m [19.6 i n ]18.6 c m [7.3 i n ]54.2 c m [21.3 i n ]35 c m [13.8 i n ]9.4 c m [3.7 i n ]43.7 c m [17.2 i n ]11.3 cm [4.4 in]26.5 cm [10.4 in]26.5 cm [10.4 in]35 c m [13.8 i n ]52 c m [20.5 i n ]77 c m [30.3 i n ]49.8 c m [19.6 i n ]Tubing and port requirementsParameter DescriptionFeed water connection½” GAZDistance from feed water port Maximum 5 m (16.4 ft)Distance from purification unit to wall-mountedQ-POD® dispenser Maximum 3 m (9.8 ft)Power entry Connection IEC13ON/OFF switch Avaliable on the unitWater sensor port Fits with standard leak detector (Cat. No. ZWATSENA1) Ethernet port IEEE P802.3Electrical connections and specificationsParameter DescriptionPower source voltage100–240 VAC ± 10%Power frequency50/60 Hz ± 2 HzPower used Maximum 115 VAPower cord length 2.5 m (8.2 ft) plug: IEC13 femaleOperational temperature4–40 °C (39–104 °F)Altitude Up to 3000 m (9842 ft)WeightsSystem type Dry weight Shipping weight Operating weight Purification unit + HMI touchscreen12.2 kg (26.9 lb)*14.6 kg (32.2 lb)16.7 kg (36.8 lb)* HMI touchscreen 0.58 kg (1.3 lb) **0.58 kg (1.3 lb)HMI touchscreen mounting kits • Benchtop• Wall 0.42 kg (0.9 lb)0.49 kg (1.1 lb)0.56 kg (1.2 lb)1.4 kg (3.0 lb)0.42 kg (0.9 lb)0.49 kg (1.1 lb)Q-POD® dispenser • System• Wall 1.2 kg (2.7 lb)2.2 kg (4.9 lb)1.5 kg (3.3 lb)2.8 kg (6.1 lb)1.2 kg (2.7 lb)2.2 kg (4.9 lb)*HMI touchscreen not included.**Included in shipping box with purification unit.HMI touchscreen specificationsScreen descriptions and functionalitiesParameter DescriptionCapacitive touchscreen Size: 7” (18 cm); Resolution: 800 x 480USB port USB 2.0 Highspeed standardDisplay in 9 languages Chinese / English / French / German / Italian /Japanese / Portuguese / Russian / Spanish12Water specifications international conformityFeed water requirementsFeed water quality Pretreated water using electrodeionization (EDI), deionization(DI), reverse osmosis (RO), or distillation technologies Pressure* < 6 barTemperature5–35 °C (41–95 °F)Conductivity ≤ 100 µS/cm at 25 °C (as NaCl)Total Organic Carbon (TOC)< 50 ppb* For pressures below 0 bar, the system will operate, but product flow rate may be lower.Ultrapure, Type 1 water specifications1 (from Q-POD® dispenser)Resistivity218.2 MΩ·cm at 25 °CConductivity 0.055 μS/cm at 25 °CTOC≤ 5 ppbParticles3No particles with size > 0.22 µmBacteria< 0.01 cfu/mL (< 10 cfu/L)(4)< 0.005 cfu/mL (< 5 cfu/L)(5)Pyrogens (endotoxins)6< 0.001 EU/mLRNases6< 1 pg/mLDNases6< 5 pg/mLProteases6< 0.15 µg/mLFlow rate Up to 2 L/min1 These values are typical and may vary depending on the nature and concentration of contaminants in the feed water.2 Resistivity can also be displayed non-temperature-compensated as required by USP.3 With Millipak® or Millipak® Gold filter.4 With Millipak® or Biopak® filter.5 With Millipak® Gold filter when installed and used in a laminar flow hood.6 With Biopak® polisher.13International regulatory requirements EU declaration of conformity – UL safety markingThe Milli-Q® EQ 7000 system has been designed and manufactured in accordance to the international standard and test method defined by the IECEE organization according CB Scheme process. CB Scheme process was applied for electromagnetic compatibility and safety compliance.The Milli-Q® EQ 7000 system is also subject of the UL listing Marking Program and meets the following marking and registration requirements listed below:• UL registration can be verified on the UL website: • Access to CB certificate: /We also meet the regulatory requirements of the following organizations:14Ordering informationSystem Catalog numberMilli-Q® EQ 7000 water purification system & HMI touchscreen ZEQ7000T0CBenchtop kit for HMI touchscreen BTEQ0DKTWall mounting kit for HMI touchscreen WMEQ0DKTSystem mounting kit for Q-POD® dispenser (includes Q-POD® unit)SMEQ00KTWall mounting Kit for Q-POD® dispenser (includes Q-POD® unit)WMEQ0RKTPure water storage tanks*Catalog numberMilli-Q® storage tank top assembly TANKT0PA1Milli-Q® storage tank, 25 L TANKA025Milli-Q® storage tank, 50 L TANKA050Milli-Q® storage tank, 100 L TANKA100* Also compatible with polyethylene (PE) storage tanks or distribution loop.Purification consumables & Application POD-Paks Catalog numberIPAK Meta®/IPAK Quanta® consumable kit IPAKKITA1Millipak® 0.22 μm filter MPGP002A1Millipak® Gold 0.22 μm sterile filter MPGPG02A1Biopak® polisher CDUFBI0A1LC-Pak® polisher LCPAK00A1EDS-Pak® polisher EDSPAK0A1VOC-Pak® polisher V0CPAK0A1UV lamp ZEQ7UVLP0For easy consumable ordering, visit/mymilliqconsumablesAccessories Catalog numberSystem wall mounting bracket SYSTFIXA1Water sensor ZWATSENA1Foot pedal ZEQ7FTPDLInternal pressure regulator + Feed conductivity cell ZEQ7C0NDCInternal pressure regulator ZF3000810Alarm relay cable ZMQ0ALCA115Lab Water Solutions© 2022 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. Merck, the vibrant M, Milli-Q, MyMilli-Q, Q-POD, Elix, IPAK Meta, IPAK Quanta, IQnano, Jetpore, Millipak,BioPak, VOC-Pak, EDS-Pak and LC-Pak are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.Lit. No. MK_BR7180ENFor more information, please visit our website:/ultrapureWe have built a unique collection of life science brands withunrivalled experience in supporting your scientific advancements.。
超纯水制造系统操作及保养手册
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如何使用本手冊
本手冊是說明如何安裝耗材，使用及保養您的Milli-Q純水系統，雖然Milli-Q系統非常容易使用，但還 是強烈建議使用者徹底閱讀本手冊，可防止系統故障，可使使用者更熟悉所有功能及操作指令。
控制面板 Q-Gard 接頭 Q-Gard 純化管柱 Quantum 純化管柱之固定閂 液晶顯示面板 發光二極體指示燈
按鍵 電源開關 電源線插頭 保險絲盒 水管接頭及零件 UF 膜殺菌口 取水槍及支撐架 產品編號、型號、序號貼紙 固定螺絲
固定夾
系統運作原理
處理過之進水（來自EDI、RO、蒸餾及去離子）進入系統後由幫浦加壓送入Q-Gard 純化管柱內。 而此純水會暴露在紫外光下（185nm 及 254nm 波長）進行水中有機物氧化及殺菌作用。 然後純水在進入 Quantum 純化管柱以達到進一步去除微量離子及氧化後有機物之殘留。 然後純化水會穿過超過濾膜（UF），而超過濾膜可有效去除水中膠體、顆粒及分子量大於 5000 以上之 有機物，而所過濾之雜質會定時沖洗方法排掉。 一組三向閥可使純水在用水位置上經過 0.22µ之濾膜（用來去除微生物及顆粒 > 0.22µ）來取得純水。 A10有機碳分析儀可從用水點前採樣並分析其結果，在product模式中會被定期採樣。
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超純水製造系統
操作及保養 手ademic Gradient Biocel Synthesis
MILLIPORE
Milli-Q - User Manual ( ) 53588765.doc
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Milli-Q Synthesis 超纯水系统中文使用说明书
Milli-Q Synthesis超强组合型详细说明：
IVF等极为困难的特殊培养以及分子生物学实验专用
Milli-Q Synthesis系结合Gradient所采用的短波UV灯(185nm)以及Biocel所采用的5,000分子量的UF 膜，其产水的TOC值可在5ppb以下(当进水的TOC值低于50ppb)，热源则低于0.001EU/ml的新型超纯水装置。
本系统特别适用在容易受到水质影响的IVF或是DNA、RNA等分子生物学实验。
当然，Milli-Q Synthesis 的产水也可使用在需高灵敏度的HPLC检测上。
功能
◆TOC数值显示
◆电阻率显示
◆水温显示
◆纯水柱更换显示
◆“A10”UV灯更换显示
◆UV灯更换提示
◆UF膜自动清洗
◆消毒提醒
◆定期循环
◆定量取水
◆取水纯度设定
◆运转状态输出
需加装“A10”TOC检测仪
技术指标
产水量 1.5L/min
电阻率18.2MΩ·cm(25℃)
总有机碳TOC 〈5ppb
热源0.001EU/mL
细菌〈1cfu/mL
颗粒〉0.22um 〈1P/mL
Elix产水作为进水，其TOC值低于50ppb
Millipore公司是驰名世界的纯水及超纯水设备制造商，根据用户的独特要求设计制造出一系列不同的纯水及超纯水系统。
其中Milli-Q系列更是所有从事化学分析、生化研究及细胞培养所不可缺少的，该系统以反渗透水、蒸馏水、Elix水或去离子水为进水，随时提供符合美国材料试验学会(ASTM)、美国病理学会(CAP)
和临床医学会(NCCLS)规定的I级(试剂级)超纯水。
a)纯化系统
将自来水作初步处理，一般包括预过滤（深层过滤及膜过滤）和反渗透或蒸馏法，而反渗透因其污染物去除率达到90%-95%以上，回收率达20%-40%以上，效益比传统纯蒸馏法更理想，因此是Milli-Q超纯水系统的理想进水。
另外，Millipore为配合日渐普及的微量分析，研制出Elix连续电流去离子系统，结合反渗透及连续电流去离子技术的优点——经济高效(R〉5MΩ·cm)，可用于一般实验室作分析用水，又因其出水质量高，如作为Milli-Q的进水，更能提高Milli-Q纯化柱的使用寿命及出水水质。
b)存储系统
纯化水在一般出水罐中储存会吸收环境中的杂质，使水质变坏。
另外，光照也会引起微生物滋生种种杂质，并且微生物会严重影响下游的超纯系统。
Millipore专利设计的储水系统能有效改善以上问题，长期保持水质，提高Milli-Q水的质量。
c)超纯水系统
将纯水作超纯化处理，出水水质可以达到电阻率：18.2MΩ·cm，总有机物〈10ppb，配合不同设计的超纯化柱，能有效去除水中的热源及有机物，适合所有高灵敏度实验的要求。
此外，Millipore的纯水及超纯水系统能外接打印机，打印出水水质资料，符合优良实验室标准(GLP)，Millipore产品更得到了ISO9002质量认证，制造工艺符合GMP规范。
最新Milli-Q超纯水系统包括：Milli-Q Academic/Biocel/Gradient/Synthesis/Element系列。
独特设计的新一代增强型Milli-Q Century超纯水系统可提供最高品质的超纯水：
根据进水水质不同和用途不同，可灵活选用不同的QG预纯化柱和QU超纯化柱
如果偶尔对热源或RNA酶有要求，可选择Pyrogard D一次性超滤柱
新的定时流量出水开关，可使取水做到定时或定量，而且流速校正简单快捷
采用POU(Point of Use)装置：伸展灵活的供水操作臂使采水操作更加方便；也可选择脚踏开关，远距离显示和取水装置，使取水和操作更加灵活方便
高精度的水质测量系统，精确测量产水的电阻率，并有TOC测量可供选择(TOC测量范围1-999ppb，符合USP24)
整机符合优良实验室标准(GLP)，备有RS232输出接口，也可选择Millipore最新的Explore Data 软件将自己的PC机与纯水系统相连，下载历史数据和水质报告，使实验室环境网络化
采用新型加压泵噪音更小，真正静音操作(1米处小于40db)
整机设计小巧即可挂墙又可在桌面上使用，也可选择分体式设计，最大程度的节约实验室空间
有最大的灵活组合性和升级性
不同的超纯水应用，对应于不同颜色的前门，改变实验室仪器单一色彩格调，增加一点轻松
以基础应用型Milli-Q Academic型为基础，对于各种不同的应用领域和不同的技术分析目的要求，可增加或调整不同的水处理组件，组合成一系列的Milli-Q超纯水系统，满足不同实验室的不同分析要求
Milli-Q超纯水系统应用简介
Milli-Q Academic
基础应用型
高效液相色谱
离子色谱
原子吸收光谱
原子发射光谱
质谱分析仪
氨基酸分析仪
PCR应用及分析
气象分析仪器
精密仪器分析用水等
高精密光学镜片冲洗
分析试剂及药品培置
Milli-Q Biocel
超滤除热源型
分子生物学及生命科学
动物细胞及植物细胞培养试管婴儿
电泳、凝胶分析
生物工程
培养基制备
Milli-Q Gradient
超低有机物型
高效液相色谱
离子色谱
气相色谱
气-质联用
总有机碳(TOC)分析
有机物分析
毛细管电泳
微电子部件的冲洗
毒理学研究
环保实验分析
Langmuir单层分析
Milli-Q Synthesis
超强组合型
环境分析实验
物理学、电化学及界面研究毒理学研究
各种高精密仪器分析
精密分析标准品、试剂
分子生物学及生命科学
试管婴儿
组织培养
动物细胞及植物细胞培养
氨基酸分析
双向电泳
Milli-Q Element
超低元素型
痕量分析，如ICP-MS、ILC、FAAS等
规格
产水流速 1.5L/min
产水电阻率18.2MΩ·cm(25℃)
TOC 〈10ppb& 〈5ppb&
热源〈0.001Eu/ml# 〈0.001Eu/ml 〈0.001Eu/ml# 〈0.001Eu/ml 〈0.001Eu/ml#
进水水质Elix、RO(反渗透)纯水、蒸馏水或去离子水
进水压力零压力进水(〈0.3bar〉
进水水温5~35℃
重量+ 16.6kg 16.9kg 17.4kg 17.7kg 19.9kg
机身大小H455W255D315mm
电导仪316L同轴式电极，电极常数为0.01cm-1
自动定量取水校正定量取水时准确度为±3%
远距离诊断可通过系统专用软件做远距离系统传输并由专业系统工程师做远距诊断
认证全系统可检附并可追溯至NIST的仪表校验证明书(ISO9001/ISO14001)
:进水的TOC值浆影响超纯水的最终TOC值。
上述的TOC值是以Elix产水作为进水，其TOC值低于50ppb. & :甚至可降至1ppb以下。
视进水条件及采样操作环境.
#:需另加装Pyrogard-D.
+:此为加装A10 TOC监测仪的重量.。