泌尿生殖系统发育课件..

(2) Development of the Testis(Y chromosome )
mesenchyme interstitial cells connective tissue sex cords Sertoli cells primordial germ cells spermatogonia
intermediate mesoderm coelomic epithelium primordial germ cells (from the yolk sac)
mesonephric ridge primary sex cords gonadal ridge
migrate
indifferent gonad
(2) The mesonephros later in the 4th week caudal to the pronephros transitory function ? mesonephric tubules mesonephric ridges mesonephric duct pronephric duct duct and a few tubules persist as genital ducts in male
3. The Malformation (1) Cryptorchidism (2) Double Uteruses and Bicornuate Uterus (3) Vaginal Atresia (4) Hermaphrodiห้องสมุดไป่ตู้ism or Intersexulity
metanephric mesoderm
metanephric tubules
ureter, renal pelvis, major & minor calyces, collecting tubules communicate
renal tubules
one end
another end invaginated by capillaries
Development of Urogenital System
intermediate mesoderm nephrogenic cords urinary system genital system
I. The Urinary System
nephrotome,nephrogenic cord
seminiferous tubules
testis
(3)Development of the Ovary ( lack
mesenchyme connective tissue epithelium cortical cords follicular cell
Y chromosome)
primordial germ cells oogonium primary oocytes
(3) The Metanephros 5th week caudal to the mesonephros permanent functional ureteric bud two sources metanephric mesoderm
mesonephric duct
ureteric bud
ejaculatory duct
(3) Development of The Female Genital Ducts
mesonephric ducts degenerate paramesonephric ducts female genital ducts cranial unfused portions uterine tubes fused portion uterus fornix portion of vagina sinus tubercle vaginal plate remaining part of vagina
Horse-shoe kidney
Polycystic kidney
Polycystic kidney
Double Ureters
Double Ureters
Ⅱ The development of Genital System 1.Development of the Testis and Ovary (1) The Indifferent Gonads:
(2) Development of The Male Genital Ducts
paramesonephric ducts degenerate mesonephric tubules efferent ductus mesonephric duct ductus epididymis, ductus deferens,
collecting tubule
nephron
2. The Urinary Bladder and Urethra cloaca
urogenital sinus (cranial) bladder
M cranial 2 parts of urethra (middle) F urethra
spongy urethra
urogenital sinus
pronephros mesonephros urinary bladder and urethra (epithelium)
metanephros (permanent kidney)
1. The Kidneys and it’s Excretory Ducts (1)The pronephros: 4th week cervical region transitory nonfunctional pronephric tubule ---- degenerate pronephric duct ---- utilized by mesonephros
primordial follicle
ovary
(4) Descent of the Gonads
posterior wall of abdomen
pelvis
inguinal canal
ovary
scrotum testis
2. Development of the Genital Ducts (1) The Indifferent Stage mesonephric ducts and tubules paramesonephric ducts(Y-shaped canal) rostral portion para- to mesonephric ducts, open into the body cavity caudal portion fuse together in the midline, caudal end projects into the dorsal wall of the urogenital sinus and produces the sinus tubercle
(caudal )
vaginal vestibule
3. The Malformations (1) Horse-shoe kidney (2) Ectopic kidney (3) Polycystic kidney (4) Double ureters
Ectopic Kidney
Horse-shoe Kidney