华东理工大学《有机化学》期末考试试卷全集

1）
Cl AlCl3 1
2)
O + HCHO + Me2NH
1
3) CH3O
CHO + HCHO 浓 OH- 1
4)
O
NH + Br
CO2C2H5
1 H3O+ 2
O
5)
CO2Et NaOEt EtOH
?
CO2Et
6)
CH3
C6H5CHCHN+(CH3)3OH-
?
CH3
7)
O
+N
H
O
1)
O
1 2) H3O+
OH
C(CH3)3
4. How would you prepare the following compounds from the starting material given?（15 分）。
1）
n C5H11CO2H 2）
n C7H15NH2
F
CH2CH2CH3
5. Describe the characteristic absorption in IR and 1H NMR(chemical shift and coupling) for the compound H2C=CHCO2C2H5（10 分）
华东理工大学 2004—2005 学年第二学期《有机化学》
期终试卷(A)(理优 03 级)
班级_________ 姓名_________ 学号__________ 成绩_________ 2005.4.29
(用英文或中文回答下列六大题)
1. Order the following compounds in each set with respect to increasing acidity and explain why?（10 points）
z
CO2H
CO2H
OCH3
OH
1
2
z
CO2H HO2C
1
2
2. Predict the reagent or product of the following reactions:（20 points）：
1)
OH-
PhCH2CHO
?
2)
CH3CH2CO2C2H5 C2H5O- ?
3)
O + HCHO + Me2NH
D
CH3
CH3
HC CH
OH HH
5. Three compounds 1 (C4H6), 2 (C4H6O),3 (C4H6O) have been prepared by the routs shown below. Suggest structures for these isomers (15 points)
CO2OH
Cl
NaNH2 ButOH
1
Cl
2
LiI 重排
3
1；1H NMR: 5.35(2H,s)，1.0(4H,s)； 13C NMR: 3different signals 2；IR: no strong peaks outside fingerprint; 1H NMR: 3.0(2H, s)，0.85(4H, t) 3；IR: 1770 cm-1 , 1H NMR: 3.02(4H, t, J=5HZ), 1.98(2H, m, J=5HZ)
6. Propose a mechanism for the following reaction（10 points）：
CH3
H+
OH
华东理工大学 2004—2005 学年第二学期《有机化学》期终试卷
(B)(理优 03 级)
班级_________ 姓名_________ 学号__________ 成绩_________ 2005.
Br
CH3
4. 1) Give three methods for converting a ketone group to methylene group 2) How would you prepare the following two compounds from the starting material given?（33 points）
2 NaOC2H5 C2H5OH
3. For following compound, Give :1）IUPAC Chinese name (the R/S designation of each chiral center should be concerned)；2）equilibrating chair conformation and indicate which one is the most stable；3）the product from the reaction with strong base by E2 process.（15 分）
(用英文或中文回答下列六大题)
1. Order the following compounds in each set with respect to increasing acidity and explain why?（10 分）。
z
CH2 CH2
1
CH CH
2
z
N
N
H
H
1
2
2. Predict the reagent or product of the following reactions:（40 分）
1
4)
1) BH3 2)H2O2 / OH-
?
5)
O
+N
H
O
1)
O
1 2) H3O+
2 NaOC2H5 C2H5 NaNO2/HCl 2) HBF4
1
7)
CH3 Cl
O+
CO2OH
1
3. For following compound, Give :1）Chinese name (the R/S designation of each chiral center should be concerned) of IUPAC；2）equilibrating chair conformation and indicate which one is the most stable；3）the product from the reaction with strong base by E2 process.（12 points）
6. Propose a mechanism for the following reaction（10 分）：
CH3CH CHCH2OH HCl CH3CHClCH2CH2OH+ CH3CH CHCH2Cl + CH3CHClCH CH2