骨肿瘤分期ppt课件

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• AJC(American Joint Committee)修订 • IUCC(International Union Against
Cancer) 国际推广
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外科分期目的
• 治疗的要求:手术时机、手术方法、切除范围的
选择;辅助治疗方法的选择
• 预后判断
• 标准化的要求:统一标准、有利于治疗资料和疗
of the expanded cortical shell
.
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Sundaram分级系统
• Group 1 lesions are radiographically benign and
do not require further investigation or treatment.
• Group 2 lesions have a high likelihood for being
benign lesions with edge characteristics ranging from well defined to poorly defined.
• Grade 2 lesions are low-grade malignant
lesions with invasive features, particularly those with total penetration of the cortex.
geographic, appearance of marginal interface zone)
• Penetration of cortex by lesion • Absence or presence of a sclerotic rim • Absence or presence and extent (if present)
surgical resection because of aggressive behavior or risk of pathologic fracture.
• Group 4 lesions are aggressive-appearing lesions
that should be considered malignant. Biopsy should be performed to confirm the histologic grade and the diagnosis.
benign, but this finding should be confirmed by means of clinical or radiographic follow-up examination.
• Group 3 lesions are benign lesions that require
• G(Histologic Grade):分级──肿瘤的外科分级
• T(Anatomic Site):肿瘤与解剖学间室的关系
• M(Metastasis):肿瘤有无转移,包括区域和远
处转移
.
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Enneking分期
• 良性骨肿瘤
1期:潜隐性 2期:活动性 3期:侵袭性
• 恶性骨肿瘤
Ⅰ期( ⅠA ⅠB ):低度恶性 Ⅱ期( Ⅱ A ⅡB ):高度恶性 Ⅲ期( Ⅲ A ⅢB ):有局部和远处转移 A:间室内; B:间室外
骨肿瘤的外科分期 Surgical Staging of Bone
Tumors
中山医院骨科 姜南春
.
1
Enneking-Musculoskeletal Tumor Staging System
.
2
骨与软组织肿瘤TNMG分期系统
• AJCC(American Joint Committee on
Cancer) 提出
.
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组织学
• 细针穿刺活检
影像引导下穿刺活检如Fluoroscopy with C-arm guidance ,CT-guided biopsy
• 切取活检 • 切除活检
.
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影像学:X-ray Lodwick 放射学分 级
• Grade 1A, 1B, and 1C lesions represent
• Grade 3 lesions are high-grade malignant
lesions with invasive, permeative, and destructive features
.
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重要的放射学征象
• Pattern of destruction (geographic or not
• Assess disease in areas not easily
visualized with radiography, eg, the spine and pelvis
效的交流(interinstitutional and interdisciplinary communication)
.
5
Βιβλιοθήκη Baidu用范围
肌肉、骨骼系统起源于间充质组织的肿瘤
.
6
排除范围
• 来源于骨髓、网状内皮组织的肿瘤
白血病、淋巴瘤、骨髓瘤、尤文肉瘤、未分化小圆细胞肉 瘤
• 转移性肿瘤
.
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Enneking──G-T-M外科分期系统
• 复杂,对手术治疗无指导价值 • 很少使用
.
3
肌肉骨骼系统肿瘤的外科分期 (MTS分期系统)
• 佛罗里达大学,Enneking,1977 • MTS(Musculoskeletal Tumor Society)
试用
• Clinical Orthopedics and Related
Research,1980
.
14
影像学:CT
• Evaluation of local disease in detail • Assessing the lungs for pulmonary
metastases
.
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CT in evaluation of local disease
Complements radiography
.
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外科分级──G
• 临床或外科分级 • 在恶性肿瘤反映生物学侵袭程度 • 组织学、放射和临床三结合
≠组织学分级──Broder’s分级
≠放射学分级──Lodwick’s分级
• G0:良性病变;G1:低度恶性;G2:高度恶性 • 恶性肿瘤外科分级通常依从于组织学分级。但是,
如组织学表现偏良性而放射和临床表现为高度侵 袭性者应定为高度恶性
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