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Unique and Shared Responses of the Gut Microbiota to Prolonged Fasting: A Comparative Study Across Five Classes of Vertebrate Hosts.
Reporter:xxx Date:2017\11\19
4、Understanding the responses of gut microorganisms to fasting is imperative, given that the gut microbiota promote host survival during periods of fasting. For example,mice and rats lacking gut microbiota (germ-free) incur higher mortality rates than conventional hosts when starved, despite similar rates of body mass loss.
Colonic samples results
1、Tilapia exhibited a continual increase in phylogenetic diversity.
Fig. 1. 1.Phylogenetic diversity of the colonic microbial communities of various hosts at different time points over prolonged fasting.
methods
The fasting time frame was divided in thirds to determine the ‘earlyfasting’ and ‘mid-fasting’time points. Within ten minutes of euthanasia, the gas trointestinal tract from the distal esophagus to the rectum was removed intact. A central section (approximately 1–2 cm in length) of each colon was removed from all host species and promptly frozen.
2、In toads, microbial diversity was 33% higher in early-fasted individuals and 51% higher in late-fasted individuals compared with nourished toads.
Fig. 1. 2.Phylogenetic diversity of the colonic microbial communities of various hosts at different time points over prolonged fasting.
来自百度文库
INTRODUCTION
1、Gut microorganisms provide a number of nutritional functions to their hosts, such as fermenting fiber and synthesizing essential amino acids . In return, hosts provide symbiotic microorganisms with a stable, protected, and nutrient-rich environment.
5、The author compared the effects of fasting on the microbial communitie of hosts from five vertebrate classes:Osteichthyes,Amphibia,Reptilia, Aves and Mammalia. The author investigated changes in the microbial communities of two gut chambers: the colon and the cecum.
3、There may be universal responses of the gut microbiota to fasting. The absence of free nutrients or physiological responses of hosts to fasting may exert similar selection on resident microorganisms and cause complementary shifts in diversity and abundances of taxa.
2、Food limitation is a physiological challenge faced by many animals that may affect their gut microbiota. First, fasting represents an ‘energy crisis’ for microorganisms due to a reduction in the availability of nutrients . Second, many animals reduce the size of their intestines in response to fasting thereby generating a ‘housing crisis’ for the microbiota.
Reporter:xxx Date:2017\11\19
4、Understanding the responses of gut microorganisms to fasting is imperative, given that the gut microbiota promote host survival during periods of fasting. For example,mice and rats lacking gut microbiota (germ-free) incur higher mortality rates than conventional hosts when starved, despite similar rates of body mass loss.
Colonic samples results
1、Tilapia exhibited a continual increase in phylogenetic diversity.
Fig. 1. 1.Phylogenetic diversity of the colonic microbial communities of various hosts at different time points over prolonged fasting.
methods
The fasting time frame was divided in thirds to determine the ‘earlyfasting’ and ‘mid-fasting’time points. Within ten minutes of euthanasia, the gas trointestinal tract from the distal esophagus to the rectum was removed intact. A central section (approximately 1–2 cm in length) of each colon was removed from all host species and promptly frozen.
2、In toads, microbial diversity was 33% higher in early-fasted individuals and 51% higher in late-fasted individuals compared with nourished toads.
Fig. 1. 2.Phylogenetic diversity of the colonic microbial communities of various hosts at different time points over prolonged fasting.
来自百度文库
INTRODUCTION
1、Gut microorganisms provide a number of nutritional functions to their hosts, such as fermenting fiber and synthesizing essential amino acids . In return, hosts provide symbiotic microorganisms with a stable, protected, and nutrient-rich environment.
5、The author compared the effects of fasting on the microbial communitie of hosts from five vertebrate classes:Osteichthyes,Amphibia,Reptilia, Aves and Mammalia. The author investigated changes in the microbial communities of two gut chambers: the colon and the cecum.
3、There may be universal responses of the gut microbiota to fasting. The absence of free nutrients or physiological responses of hosts to fasting may exert similar selection on resident microorganisms and cause complementary shifts in diversity and abundances of taxa.
2、Food limitation is a physiological challenge faced by many animals that may affect their gut microbiota. First, fasting represents an ‘energy crisis’ for microorganisms due to a reduction in the availability of nutrients . Second, many animals reduce the size of their intestines in response to fasting thereby generating a ‘housing crisis’ for the microbiota.