电渗析技术清洁分离纯化肌氨酸_汪耀明

2015年8月 CIESC Journal

August 2015第

66卷 第8期 化 工 学 报 V ol.66 No.8

电渗析技术清洁分离纯化肌氨酸

汪耀明1，李为2，徐铜文1

（1中国科学技术大学化学与材料科学学院，安徽 合肥230026；2合肥科佳高分子材料科技有限公司，安徽 合肥 230601）

摘要：肌氨酸作为一种高附加值的精细化工产品具有广泛的应用前景。目前肌氨酸的生产过程中存在肌氨酸产品与无机盐的分离过程。传统的分离方法为分步结晶法，存在能耗高、消耗的化学试剂多、污染大等缺点。为实现肌氨酸的清洁生产，本文采用自制电渗析装置对肌氨酸进行分离纯化，考察了操作电流以及溶液起始pH 对整个分离效果的影响。结果表明，当操作电流为2 A ，起始pH 为6.5时，电渗析过程中无机盐的去除率大于99%，其产品得率为71.5%，电渗析工艺生产肌氨酸的能耗为26.4 kW ·h ·t −1，总成本仅为311元·t −1，大大优于传统的生产工艺。由此可见，电渗析工艺可实现肌氨酸产品的节能、环保生产。 关键词：离子交换膜；电渗析；肌氨酸；清洁生产 DOI ：10.11949/j.issn.0438-1157.20150701

中图分类号：TQ 028.8 文献标志码：A 文章编号：0438—1157（2015）08—3137—07

Electrodialysis for cleaner separation and purification of sarcosine

WANG Yaoming 1, LI Wei 2, XU Tongwen 1

(1School of Chemistry and Material Science , University of Science and Technology of China , Hefei 230026, Anhui , China ;

2

Hefei ChemJoy Polymer Materials Co ., Ltd , Hefei 230601, Anhui , China )

Abstract : Sarcosine is a high-value fine chemical which has many significant applications. Now there is a separation process to remove the inorganic salts from the target product during the production of sarcosine. Multistage fractional crystallization is the conventional separation technology for sarcosine production which has many drawbacks such as high energy consumption, large consumption of chemicals and environmental pollution. To achieve cleaner production of sarcosine, a self-made electrodialysis stack was used in the separation and purification of the target product. The influences of current density and initial pH value in the feed solution on the production of sarcosine were investigated. Results indicated that salt removal rates higher than 99% and a product recovery ratio of 71.5% can be obtained at a current of 2 A and initial feed solution of pH 6.5. The total energy

consumption for sarcosine production was 26.4 kW ·h ·t −1 and the total process cost was estimated at 311 ￥·t −1, which is much less than the conventional separation technologies. It can be seen that electrodialysis is not only

energy-saving but also environment- friendly for the industrial production of sarcosine. Key words : ion exchange membrane; electrodialysis; sarcosine; cleaner production

引 言

肌氨酸，又名N -甲基甘氨酸，是合成肌酸的中

间体，传统上是作为工业用品染料稳定剂和日用化

学品氨基酸型表面活性剂[1]。同时，肌氨酸还有一些独特的生理功能，如提高人的智力、增加肌肉无

2015-05-25收到初稿，2015-06-08收到修改稿。

联系人：徐铜文。第一作者：汪耀明（1984—），男，博士，副研究员。

基金项目：国家自然科学基金项目（21276247，21476220）。

Received date : 2015-05-25.

Corresponding author : Prof.XU Tongwen, twxu@ Foundation item : supported by the National Natural Science Foundation of China (21276247, 21476220).