亚低温治疗新生儿重度窒息的效果

国际医药卫生导报 2019年 第25卷 第11期　IMHGN，June 2019，Vol. 25　No. 11

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（收稿日期：2019-04-20）

（责任校对：成观星）

新生儿窒息的产生在临床上具有较高的发生率，其对新生儿的生命安全有着较大的威胁[1]。新生儿重度窒息是因胎儿在宫内发生缺氧、窘迫症状，或者胎儿在娩出过程中所引起的呼吸循环障碍所导致的疾病。此病会导致新生儿在出生后1 min，仅会出现心跳现象，而无法建立规律的呼吸，致使新生儿

亚低温治疗新生儿重度窒息的效果

谭翠玲

广州市番禺区何贤纪念医院新生儿科　511483

【摘要】　目的　研究亚低温治疗新生儿重度窒息效果。方法　随机选取2016年1月至2018年8

月在本院接受治疗的新生儿重度窒息患儿22例，根据对新生儿重度窒息患儿实施治疗方式的不同将患儿

分为对照组与亚低温组。对照组常规治疗，亚低温组亚低温治疗，比较两组疗效。结果　治疗24、72 h，

亚低温组心率优于对照组（P＜0.05），而呼吸、收缩压与对照组差异无统计学意义（均P＞0.05）；治

疗后，亚低温组ALT、AST、BUN、Cr、PT、TT等指标显优于对照组（均P＜0.05）；治疗后，亚低温

组存活率为90.91%，明显高于对照组的存活率（72.72%），差异有统计学意义（P＜0.05）。结论　对

新生儿重度窒息患儿实施亚低温治疗，能够提升患儿身体机能，降低患儿病死率，值得推广应用。

【关键词】　新生儿重度窒息；亚低温治疗；疗效；安全性

DOI：10.3760/cma.j.issn.1007-1245.2019.11.041

Hypothermia in treatment of neonates with severe asphyxia

Tan Cuiling

Department of Neonatology, He Xian Memorial Hospital, Panyu District, Guangzhou 511483, China

【Abstract】Objective To study the effect of mild hypothermia in the treatment of neonates with severe

asphyxia. Methods Twenty-two children with severe asphyxia treated in our hospital from January, 2016 to

August, 2018 were selected and divided into a control group and a hypothermia group according to different

treatment methods. The control group were routinely treated, and the hypothermia group were treated with hypothermia. The treatment effects were compared. Results After 24 and 72 h treatment, the heart rates were

lower in the hypothermia group than in the control group (both P＜0.05); and there were no statistical differences

in respiratory and systolic blood pressure between these two group (all P＞0.05). After treatment, the ALT, AST,

BUN, Cr, PT, and TT were significantly better in the hypothermia group than in the control group (all P＜0.05).

After treatment, the survival rate was 90.91% in hypothermia group, and was 72.72% in the control group (P

＜0.05). Conclusion Hypothermia for children with severe asphyxia can improve the children’s physical function

and reduce their mortality, so it was worth for popularization and application.

【Key words】 Neonatal severe asphyxia; Hypothermia treatment; Efficacy; Safety

DOI：10.3760/cma.j.issn.1007-1245.2019.11.041

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