分子遗传学第7章基因突变与重组-遗传学
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GTGGAACCCTTTGGAGCTGTCCCTAGGCAAAGGGAAGAAGGGGAAGATTGATTCAAAATCAACTTCATTTCATT
CCATTACTTTTATATTTGTTTTATTTTTTTTTTTTAATAACCAAGAAAAA
12
MSSFSVRFFAPQQPLLPSTASSFKPKTWVMAAPTTAPATSVDVD GQRLEPRVEEREGYFVLKEKFRDGINPQEKIKIEKDPLKLFMEAG IDELAKMSFEDIDKAKATKDDIDVRLKWLGLFHRRKHQYGRFM MRLKLPNGVTTSAQTRYLASVIRKYGKEGCADVTTRQNWQIRG VVLPDVPEILKGLDEVGLTSLQSGMDNVRNPVGNPLAGIDPEEIV DTRPYTNLLSQFITANSRGNPAFANLPRKWNVCVVGSHDLYEHP HINDLAYMPATKNGRFGFNLLVGGFFSAKRCDEAIPLDAWVSAD DVIPLCKAVLEAYRDLGYRGNRQKTRMMWLIDELGIEVFRSEVA KRMPQKELERASDEDLVQKQWERRDYLGVHPQKQEGFSYIGIH IPVGRVQADDMDELARLADTYGSGEFRLTVEQNIIIPNVENSKLE ALLNEPLLKDRFSPQPSILMKGLVACTGNQFCGQAIIETKARALK VTEEVERLVSVSRPVRMHWTGCPNTCGQVQVADIGFMGCMAR DENGKPCEGADIFLGGRIGSDSHLGELYKKGVPCKNLVPVVADIL VEPFGAVPRQREEGED
CAACAAAACCCCACATGTCTTCCTTTTCGGTCCGTTTCTTTGCTCCACAACAGCCGTTACTGCCGTCCACAGCTTC
CTCTTTCAAGCCCAAAACATGGGTTATGGCAGCTCCCACGACGGCGCCAGCGACTTCGGTGGATGTCGACGGGC AGAGGTTGGAACCCCGAGTTGAAGAACGAGAGGGGTACTTCGTGTTGAAAGAGAAGTTCAGAGATGGCATCAAC CCTCAAGAGAAAATAAAGATCGAGAAAGACCCTTTGAAGCTTTTCATGGAAGCTGGGATTGATGAACTCGCTAAGA TGTCGTTCGAGGATATTGATAAAGCTAAGGCTACAAAGGACGACATTGATGTTAGACTTAAATGGCTCGGCTTGTT CCATAGGAGAAAACATCAATATGGGAGATTTATGATGAGATTAAAACTACCAAATGGTGTAACAACAAGTGCACAA ACACGGTACTTAGCCAGTGTGATAAGGAAATACGGCAAAGAAGGGTGTGCAGATGTTACGACAAGGCAAAACTG GCAAATCCGTGGAGTGGTGTTGCCTGATGTGCCTGAAATACTTAAGGGTCTCGACGAAGTAGGCTTGACGAGCCT ACAGAGTGGCATGGACAATGTGAGGAACCCTGTTGGTAATCCTCTTGCCGGCATCGACCCCGAAGAGATTGTCGA TACTCGACCTTATACCAACTTGTTATCTCAGTTCATCACCGCCAATTCCCGCGGCAATCCGGCTTTTGCCAACTTGC CTAGGAAATGGAATGTCTGTGTCGTGGGGTCTCATGATCTTTACGAACATCCCCATATCAATGATCTCGCTTATATG CCGGCGACGAAAAACGGACGATTTGGGTTTAATTTGCTGGTTGGTGGGTTCTTTAGTGCCAAGAGATGTGATGAG GCCATTCCTCTTGATGCTTGGGTCTCAGCTGATGATGTGATTCCATTGTGCAAAGCTGTGTTAGAAGCCTATAGGG ATCTTGGATACAGGGGCAATAGGCAAAAGACTAGAATGATGTGGCTGATTGATGAACTGGGTATTGAAGTGTTCA GATCAGAAGTAGCCAAAAGAATGCCTCAGAAAGAGTTGGAGAGAGCATCTGATGAAGATTTGGTTCAAAAGCAAT GGGAAAGGAGAGACTACCTTGGTGTCCATCCGCAAAAGCAAGAAGGTTTCAGCTACATCGGCATTCACATCCCAG TCGGTCGAGTCCAAGCCGACGACATGGACGAACTAGCCCGGTTAGCCGACACGTATGGCTCGGGCGAATTCAGA CTCACTGTGGAGCAAAACATCATAATCCCCAACGTTGAGAACTCGAAACTAGAAGCATTACTAAACGAGCCTCTAT TGAAAGACCGGTTTTCACCCCAACCAAGTATTCTCATGAAAGGGCTAGTAGCTTGTACTGGTAACCAGTTTTGCGG ACAAGCCATTATTGAAACAAAAGCTAGAGCCTTGAAGGTGACGGAAGAGGTTGAAAGGCTAGTGTCGGTGAGCC GGCCGGTGAGGATGCATTGGACCGGTTGCCCCAACACGTGTGGTCAAGTCCAAGTGGCGGATATAGGTTTCATG GGGTGCATGGCAAGGGATGAGAATGGGAAACCATGTGAAGGGGCAGACATATTTTTGGGAGGGAGAATTGGGAG TGACTCCCATTTAGGAGAGCTTTATAAGAAGGGTGTCCCTTGTAAGAACTTGGTACCTGTAGTTGCTGACATTTTG
第7 章 突变 （Mutation ）
生物多样性的形成是以基因突变和遗传重组为基础，自然选择的进化结果。
1
中心法则(central dogma)
RNA 复制
复制 DNA 转录
逆转录
翻译
RNA
蛋白质
2
3
4Leabharlann Baidu
启动序列 (promoter)
编码序列
其他调节序列
蛋白质因子
操纵序列 (operator)
特异DNA序列
5
6
7
8
9
10
11
AGAATTTTCTAACTAAAAGTTCATAAGACAAACCCAAACATTGTCATGTTTCTCGGTTCTTTCTTACAACCCAAGCT GACCCTTAACATCATCGAAGAGTCCCCCCCACCGAAAGCCCTCCCCTCTGCTCTTAAAGTCCCCTTCATTCCATTAC AAAAATGTCCGAACTCTGATATCCCTTCACTTATCTTTCCACCACCACAATTCCACCAGTTCCAAGCTTCTTTTCAAA
CCATTACTTTTATATTTGTTTTATTTTTTTTTTTTAATAACCAAGAAAAA
12
MSSFSVRFFAPQQPLLPSTASSFKPKTWVMAAPTTAPATSVDVD GQRLEPRVEEREGYFVLKEKFRDGINPQEKIKIEKDPLKLFMEAG IDELAKMSFEDIDKAKATKDDIDVRLKWLGLFHRRKHQYGRFM MRLKLPNGVTTSAQTRYLASVIRKYGKEGCADVTTRQNWQIRG VVLPDVPEILKGLDEVGLTSLQSGMDNVRNPVGNPLAGIDPEEIV DTRPYTNLLSQFITANSRGNPAFANLPRKWNVCVVGSHDLYEHP HINDLAYMPATKNGRFGFNLLVGGFFSAKRCDEAIPLDAWVSAD DVIPLCKAVLEAYRDLGYRGNRQKTRMMWLIDELGIEVFRSEVA KRMPQKELERASDEDLVQKQWERRDYLGVHPQKQEGFSYIGIH IPVGRVQADDMDELARLADTYGSGEFRLTVEQNIIIPNVENSKLE ALLNEPLLKDRFSPQPSILMKGLVACTGNQFCGQAIIETKARALK VTEEVERLVSVSRPVRMHWTGCPNTCGQVQVADIGFMGCMAR DENGKPCEGADIFLGGRIGSDSHLGELYKKGVPCKNLVPVVADIL VEPFGAVPRQREEGED
CAACAAAACCCCACATGTCTTCCTTTTCGGTCCGTTTCTTTGCTCCACAACAGCCGTTACTGCCGTCCACAGCTTC
CTCTTTCAAGCCCAAAACATGGGTTATGGCAGCTCCCACGACGGCGCCAGCGACTTCGGTGGATGTCGACGGGC AGAGGTTGGAACCCCGAGTTGAAGAACGAGAGGGGTACTTCGTGTTGAAAGAGAAGTTCAGAGATGGCATCAAC CCTCAAGAGAAAATAAAGATCGAGAAAGACCCTTTGAAGCTTTTCATGGAAGCTGGGATTGATGAACTCGCTAAGA TGTCGTTCGAGGATATTGATAAAGCTAAGGCTACAAAGGACGACATTGATGTTAGACTTAAATGGCTCGGCTTGTT CCATAGGAGAAAACATCAATATGGGAGATTTATGATGAGATTAAAACTACCAAATGGTGTAACAACAAGTGCACAA ACACGGTACTTAGCCAGTGTGATAAGGAAATACGGCAAAGAAGGGTGTGCAGATGTTACGACAAGGCAAAACTG GCAAATCCGTGGAGTGGTGTTGCCTGATGTGCCTGAAATACTTAAGGGTCTCGACGAAGTAGGCTTGACGAGCCT ACAGAGTGGCATGGACAATGTGAGGAACCCTGTTGGTAATCCTCTTGCCGGCATCGACCCCGAAGAGATTGTCGA TACTCGACCTTATACCAACTTGTTATCTCAGTTCATCACCGCCAATTCCCGCGGCAATCCGGCTTTTGCCAACTTGC CTAGGAAATGGAATGTCTGTGTCGTGGGGTCTCATGATCTTTACGAACATCCCCATATCAATGATCTCGCTTATATG CCGGCGACGAAAAACGGACGATTTGGGTTTAATTTGCTGGTTGGTGGGTTCTTTAGTGCCAAGAGATGTGATGAG GCCATTCCTCTTGATGCTTGGGTCTCAGCTGATGATGTGATTCCATTGTGCAAAGCTGTGTTAGAAGCCTATAGGG ATCTTGGATACAGGGGCAATAGGCAAAAGACTAGAATGATGTGGCTGATTGATGAACTGGGTATTGAAGTGTTCA GATCAGAAGTAGCCAAAAGAATGCCTCAGAAAGAGTTGGAGAGAGCATCTGATGAAGATTTGGTTCAAAAGCAAT GGGAAAGGAGAGACTACCTTGGTGTCCATCCGCAAAAGCAAGAAGGTTTCAGCTACATCGGCATTCACATCCCAG TCGGTCGAGTCCAAGCCGACGACATGGACGAACTAGCCCGGTTAGCCGACACGTATGGCTCGGGCGAATTCAGA CTCACTGTGGAGCAAAACATCATAATCCCCAACGTTGAGAACTCGAAACTAGAAGCATTACTAAACGAGCCTCTAT TGAAAGACCGGTTTTCACCCCAACCAAGTATTCTCATGAAAGGGCTAGTAGCTTGTACTGGTAACCAGTTTTGCGG ACAAGCCATTATTGAAACAAAAGCTAGAGCCTTGAAGGTGACGGAAGAGGTTGAAAGGCTAGTGTCGGTGAGCC GGCCGGTGAGGATGCATTGGACCGGTTGCCCCAACACGTGTGGTCAAGTCCAAGTGGCGGATATAGGTTTCATG GGGTGCATGGCAAGGGATGAGAATGGGAAACCATGTGAAGGGGCAGACATATTTTTGGGAGGGAGAATTGGGAG TGACTCCCATTTAGGAGAGCTTTATAAGAAGGGTGTCCCTTGTAAGAACTTGGTACCTGTAGTTGCTGACATTTTG
第7 章 突变 （Mutation ）
生物多样性的形成是以基因突变和遗传重组为基础，自然选择的进化结果。
1
中心法则(central dogma)
RNA 复制
复制 DNA 转录
逆转录
翻译
RNA
蛋白质
2
3
4Leabharlann Baidu
启动序列 (promoter)
编码序列
其他调节序列
蛋白质因子
操纵序列 (operator)
特异DNA序列
5
6
7
8
9
10
11
AGAATTTTCTAACTAAAAGTTCATAAGACAAACCCAAACATTGTCATGTTTCTCGGTTCTTTCTTACAACCCAAGCT GACCCTTAACATCATCGAAGAGTCCCCCCCACCGAAAGCCCTCCCCTCTGCTCTTAAAGTCCCCTTCATTCCATTAC AAAAATGTCCGAACTCTGATATCCCTTCACTTATCTTTCCACCACCACAATTCCACCAGTTCCAAGCTTCTTTTCAAA