鹅去氧胆酸信息
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CDCA
鹅去氧胆酸(CDCA)主要作用是降低胆汁内胆固醇的饱和度,绝大多数患者服用CDCA后(当CDCA占胆汁中胆盐的70%时),脂类恢复微胶粒状态,胆固醇就处于不饱和状态,从而使结石中的胆固醇溶解、脱落。大剂量的CDCA(每日10~15mg/kg)可以抑制胆固醇的合成,并增加胆石症患者胆汁的分泌,但其中的胆盐和磷脂分泌量维持不变。
The main role of chenodeoxycholic acid (CDCA) is to reduce the saturation of cholesterol in the bile. Most patients take CDCA (when CDCA accounts for 70% of bile salts in bile), lipids return to the state of microcapsules, cholesterol will be in an unsaturated state, so that the cholesterol in the stone dissolves and falls off. Large doses of CDCA (10-15 mg/kg per day) can inhibit the synthesis of cholesterol and increase the secretion of bile in patients with cholelithiasis, but the amount of bile salts and phospholipids remains unchanged.
通用名鹅去氧胆酸
英文名CHENODEOXYCHOLIC ACID(CHENODESOXYCHOLIC ACID)
拼音名EQUYANDANSUAN PIAN
药品类别肝胆病用药
CAS:474-25-9[1]
性状无色针状结晶,无味。在水中不易溶解。
贮藏避光,密闭保存。
包装片剂:0.25g/片。
Common name chenodeoxycholic acid
English name CHENODEOXYCHOLIC ACID (CHENODESOXYCHOLIC ACID)
Pinyin name EQUYANDANSUAN PIAN
Drug Category Hepatobiliary Drugs
CAS: 474-25-9 [1]
Characters Colorless needle crystals, odorless. Not easily soluble in water.
Store in the dark, sealed and stored.
Packaging Tablets: 0.25 g / tablet.
主要成分
结构式
结构式
通用名鹅去氧胆酸
化学名3α,7α-二羟基-5β-胆烷酸
拼音名 E QU YANG DAN SUAN
英文名CHENODEOXYCHOLIC ACID
CAS No. 474-25-9
分子式C24H40O4
分子量392.56
Main ingredient
Structural formula
Structural formula
Common name chenodeoxycholic acid Chemical name 3α,7α-dihydroxy-5β-cholanoic acid Pinyin name E QU YANG DAN SUAN
English name CHENODEOXYCHOLIC ACID
CAS No. 474-25-9
Molecular formula C24H40O4
Molecular weight 392.56
安全信息
∙RTECS号:FZ1980000
∙WGKGermany:2
∙安全说明:S22-S24/25-S45-S36/37 ∙海关编码:2918990090
∙危险品标志:Xn:Harmful
∙危险类别码:R63