欧洲皮肤病学论坛-局部光动力疗法指南

doi:10.1684/ejd.2015.2570

Therapy

Eur J Dermatol 2015;25(4):296-311

Colin MORTON 1

Rolf-Markus SZEIMIES 2Alexis SIDOROFF 3

Ann-Marie WENNBERG 4Nicole BASSET-SEGUIN 5Piergiacomo

CALZA V ARA-PINTON 6Yolanda GILABERTE 7Günther HOFBAUER 8Robert HUNGER

9Sigrid KARRER 10Percy LEHMANN 11Stefano PIASERICO 12Claas ULRICH 13

Lasse BRAATHEN 9,

on behalf of the European Dermatology Forum

1

Department of Dermatology,Stirling Community Hospital,Stirling,FK82AU,UK

2Department of Dermatology &Allergology,

Knappschaftskrankenhaus Recklinghausen,Recklinghausen,Germany

3Department of Dermatology and Venereology,

Medical University Innsbruck,Austria

4Department of Dermatology,Sahlgrenska University Hospital,Gothenburg,Sweden

5Department of Dermatology,Hôpital Saint Louis,Paris,France

6Department of Dermatology,Spedali Civili,Brescia,Italy 7Department of Dermatology,Hospital San Jorge,Huesca,Spain

8Department of Dermatology,

Zurich University Hospital,Zürich,Switzerland

9Department of Dermatology Bern,Bern,Switzerland

10Department of Dermatology,University Hospital Regensburg,Regensburg,Germany

11Department of Dermatology,HELIOS Klinikum Wuppertal,Germany

12Unit of Dermatology,Department of Medicine,University of Padova,Italy 13Skin Cancer Centre,Hautklinik der Charitie,Berlin,Germany

Reprints:C.Morton

Article accepted on 15/3/2015

European Dermatology Forum Guidelines on topical photodynamic therapy

Topical photodynamic therapy (PDT)is a widely approved therapy for actinic keratoses,squamous cell carcinoma in-situ ,superficial and cer-tain thin basal cell carcinomas.Recurrence rates are typically equivalent to existing therapies,although inferior to surgery for nodular basal cell carcinoma.PDT can be used both as a lesional or as a field therapy and has the potential to delay/reduce the development of new lesions.PDT has also been studied for its place in the treatment of,as well as its poten-tial to prevent,superficial skin cancers in immune-suppressed patients,although sustained clearance rates are lower than for immunocompetent individuals.Many additional indications have been evaluated,including photo-rejuvenation and inflammatory and infective dermatoses.This S2guideline considers all current and emerging indications for the use of topical photodynamic therapy in Dermatology,prepared by the PDT subgroup of the European Dermatology Forum guidelines committee.It presents consensual expert recommendations reflecting current pub-lished evidence.An unabridged version of this guideline is available online at:/edf/index.php/edf-guidelines.Key words:5-aminolaevulinic acid,dermatology,guidelines,methyl aminolaevulinate,non-melanoma skin cancer,photodynamic therapy