补肾疏肝汤治疗肾虚肝郁型更年期综合征临床疗效观察-郭彦

209

第18卷 第5期 2016 年 5 月

辽宁中医药大学学报

JOURNAL OF LIAONING UNIVERSITY OF TCM

Vol. 18 No. 5 May，2016

补肾疏肝汤治疗肾虚肝郁型更年期综合征临床疗效观察

郭彦

（辽宁中医药大学附属第四医院，辽宁 沈阳 110101）

摘 要：

目的：探究补肾疏肝汤治疗肾虚肝郁型更年期综合征的临床疗效。方法：选取我院妇产科收治的肾虚肝郁型更年期综合征患者76例，采用随机数字表随机分为2组，每组38例患者，其中对照组38例，给予盐酸帕罗西汀片进行治疗，2周为1个疗程，治疗3个疗程；实验组38例，给予自拟补肾疏肝汤进行治疗，2周为1个疗程，治疗3个疗程。治疗结束后，对比患者的临床疗效及抑郁症状评分，对比患者雌激素水平。结果：①治疗后两组患者各临床症状比较，实验组较对照组改善明显，检测临床总有效率可知，实验组临床总有效率为89.5%，对照组临床总有效率为78.9%，两组结果差异有统计学意义（P <0.05）；②治疗结束后，两组患者抑郁症状评分显示，实验组较对照组有明显减少，两组结果差异有统计学意义（P <0.05）；③治疗结束后，检测患者E 2、FSH、LH 等激素水平，结果显示E 2水平有明显上升，FSH 及LH 水平有明显下降，实验组各指标变化较对照组明显，两组结果差异有统计学意义（P <0.05）。结论：补肾疏肝汤可通过调节患者体质，改善肾气不足、肝气郁滞之症，可调节患者体内雌性激素水平，缓解患者抑郁情绪，有效治疗肾虚肝郁型更年期综合征，值得临床推广。

关键词：补肾疏肝汤；肾虚肝郁型；更年期综合征；临床疗效

中图分类号：R588 文献标志码：A 文章编号：1673-842X (2016) 05- 0209- 04

收稿日期：2015-10-28

作者简介：郭彦（1982-），女，辽宁沈阳人，讲师、主治医师，硕士，研究方向：中医妇产科疾病。

Tonifing Kidney Soothing Liver Decoction Treatment Kidney Liver Depression

Type of the Clinical Effect of the Treatment of Menopausal Syndrome

GUO Yan

（The Fourth Affiliated Hospital of Liaoning University of Traditional

Chinese Medicine，Shenyang 110101，Liaoning，China）

Abstract：Objective ：To explore the tonifing kidney soothing liver decoction treatment the clinical

curative effect of kidney liver depression type of menopause syndrome. Methods ：Our hospital for kidney liver depression patients with climacteric syndrome of 76 cases with random number table were randomly divided into two groups，each group of 38 cases，control group in which 38 cases，give paroxetine hydrochloride treatment，2 weeks for a period of treatment，the treatment of 3 courses；experimental group 38 cases，give tonifing kidney soothing liver decoction treatment，2 weeks for a period of treatment，treatment 3 period of treatment. After treatment，the contrast of the patient's clinical curative effect and depression symptom scores，compared to patients with estrogen levels. Results ：（1）In the two groups after treatment in patients with the clinical symptoms were improved，detection of clinical curative effect，clinical total effective rate was 89.5%，while the control group total effective rate was 78.9%，the results are similar between the two groups have statistical significance（P <0.05）；（2）In the two groups after treatment in patients with depressive symptoms significantly reduce，improved score shows that the experimental group than the control group，the results are similar between the two groups have statistical significance（P <0.05）；end testing patients treated（E 2，FSH，LH，such as hormone levels，the result shows that the experimental group E 2 levels increased compared with control group，experimental group FSH，LH levels have significantly lower than the control group，the results are similar between the two groups have statistical significance（P <0.05）. Conclusion ：Patients with tonifing kidney soothing liver decoction can be adjusted by constitution，qi improve kidney deficiency and liver stasis of disease，patients with adjustable level of estrogen in the body，relieve depression patients，effective treatment for kidney liver depression type of menopause syndrome，worth clinical promotion.

Keywords：tonifing kidney soothing liver decoction；kidney liver depression model；menopausal syndrome；clinical efficacy 更年期综合征又称围绝经期综合征，是指出现于妇女绝经前后因性激素异常所引起的一系列躯体、精神、心理症状，本病属于情感性精神障碍疾病，临床表现以心情抑郁、汗出、紧张焦虑、情绪波动大、

失眠早醒等为主要表现[1]。现代研究表明更年期妇

女卵巢功能减退，卵巢分泌雌二醇（E 2）减少，FSH、LH 等激素水平升高，雌激素水平降低，引起各神经、内分泌、免疫、下丘脑、垂体等网络功能紊乱，最终

DOI：10.13194/j.issn.1673-842x.2016.05.069