NMI N-甲基咪唑

N-甲基咪唑（NMI）N-甲基咪唑试剂级价格

N-甲基咪

唑CAS号: 616-47-7

英文名称: 1-Methylimidazole

英文同义词: MIM;DY 070;NSC 88064;LUPRAGEN(R) NMI;Araldite DY 070;methyl imidazole;1-Methylimdazole;1-

methyl-imidazo;1-methylmidazole;1-

METHYLIMIDAZOLE

中文名称: N-甲基咪唑

中文同义词: 甲基咪唑;1-甲基咪;1-甲咪唑;甲基引咪唑;1-甲基

咪唑;N-甲基咪唑;1-甲基甘噁啉;56-37-1%;1-甲基

咪唑溶液;1-甲基-1H-咪唑

CBNumber: CB1316726

分子式: C4H6N2

分子量: 82.1

MOL File: 616-47-7.mol

N-甲基咪唑化学性质

熔点: −60 °C(lit.)

沸点: 198 °C(lit.)

密度: 1.03 g/mL at 25 °C(lit.)

蒸气压: 0.4 mm Hg ( 20 °C)

折射率: n20/D 1.495(lit.)

闪点: 198 °F

储存条件: Store at RT.

敏感性: Hygroscopic

BRN : 105197

稳定性: Stable, but moisture sensitive. Incompatible

with acids, acid anhydrides, strong oxidizing

agents, moisture, carbon dioxide, acid

chlorides.

CAS 数据库: 616-47-7(CAS DataBase Reference)

NIST化学物质信息: 1H-Imidazole, 1-methyl-(616-47-7)

EPA化学物质信息: 1H-Imidazole, 1-methyl-(616-47-7)

安全信息

危险品标志: C,Xn,F,T

危险类别码: 21/22-34-19-11-20/21/22-52/53-24-22-40-37-21安全说明: 26-36-45-1/2-36/37/39-16-33-29-61

危险品运输编号: UN 3267 8/PG 2

WGK Germany : 1

RTECS号: NI7000000

F : 3-10

HazardClass : 8

PackingGroup : III

海关编码: 29332990

N-甲基咪唑 MSDS

1-Methyl-1H-imidazole

N-甲基咪唑性质、用途与生产工艺

化学性质

外观：无色透明液体，熔点：-60℃，沸点：198℃，密度

d20/4=1.036g/ml。含量：≥99% 。

用途

主要用于环氧树脂和其它树脂的固化剂；用于浇注、粘接和玻璃钢等领域。

用途

有机合成中间体和树脂固化剂、粘合剂等。可用于浇注、粘接和玻璃钢等领域。

用途

用作有机合成中间体和树脂固化剂、粘合剂等

N-甲基咪唑上下游产品信息

上游原料

咪唑4-氯-3-硝基苯甲酸碳酸二甲酯

下游产品

1-乙基-3-甲基咪唑四氟硼酸盐1-甲基-1H-咪唑-2-甲醛1-甲基-1H-咪唑-2-羰酰氯1-丁基-3-甲基咪唑四氟硼酸盐盐酸萘甲唑啉1-甲基-1H-咪唑-2-甲酸乙酯1-乙基-3-甲基咪唑二氨腈,98%毒死蜱硝唑芬酮1-丁基-3-甲基咪唑溴盐1-丁基-3-甲基咪唑六氟磷酸盐1-甲基-1H-咪唑-2-羧酸1-甲基咪唑-5-甲酰氯盐酸盐1-乙基-3-甲基咪唑啉双(三氟甲基磺酰基)亚胺洛沙坦甲基毒死蜱2-(1-甲基-1H-咪唑-2-基)-2-羰基乙酸乙酯

1-Methylimidazole

From Wikipedia, the free encyclopedia

616-47-7

CHEBI:113454

ChEMBL543

1348

verify (what is ?)

1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colourless liquid that is used as a specialty solvent, a base, and as a precursor to some ionic liquids. It is a fundamental nitrogen heterocycle and as such mimics for various nucleoside bases as well as histidine and histamine,

Contents

[hide]

∙1Basicity

∙2Synthesis

∙3Applications

o 3.1Ionic liquid precursor

∙4See also

∙5References

Basicity[edit]

With the N-methyl group, this particular derivative of imidazole cannot tautomerize. It is slightly more basic than imidazole, as indicated by the pKa's of the conjugate acids of 7.0 and 7.4.[1] Methylation also provides a significantly lower melting point, which makes 1-methylimidazole a useful solvent.

Synthesis[edit]

1-Methylimidazole is prepared mainly by two routes industrially. The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine.[2][3]

(CHO)2 + CH2O + CH3NH2 + NH3→ H2C2N(NCH3)CH + 3 H2O

The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation.[4] Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation.[5][6]

H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I