NMI N-甲基咪唑

N-甲基咪唑（NMI）N-甲基咪唑试剂级价格
N-甲基咪
唑CAS号: 616-47-7
英文名称: 1-Methylimidazole
英文同义词: MIM;DY 070;NSC 88064;LUPRAGEN(R) NMI;Araldite DY 070;methyl imidazole;1-Methylimdazole;1-
methyl-imidazo;1-methylmidazole;1-
METHYLIMIDAZOLE
中文名称: N-甲基咪唑
中文同义词: 甲基咪唑;1-甲基咪;1-甲咪唑;甲基引咪唑;1-甲基
咪唑;N-甲基咪唑;1-甲基甘噁啉;56-37-1%;1-甲基
咪唑溶液;1-甲基-1H-咪唑
CBNumber: CB1316726
分子式: C4H6N2
分子量: 82.1
MOL File: 616-47-7.mol
N-甲基咪唑化学性质
熔点: −60 °C(lit.)
沸点: 198 °C(lit.)
密度: 1.03 g/mL at 25 °C(lit.)
蒸气压: 0.4 mm Hg ( 20 °C)
折射率: n20/D 1.495(lit.)
闪点: 198 °F
储存条件: Store at RT.
敏感性: Hygroscopic
BRN : 105197
稳定性: Stable, but moisture sensitive. Incompatible
with acids, acid anhydrides, strong oxidizing
agents, moisture, carbon dioxide, acid
chlorides.
CAS 数据库: 616-47-7(CAS DataBase Reference)
NIST化学物质信息: 1H-Imidazole, 1-methyl-(616-47-7)
EPA化学物质信息: 1H-Imidazole, 1-methyl-(616-47-7)
安全信息
危险品标志: C,Xn,F,T
危险类别码: 21/22-34-19-11-20/21/22-52/53-24-22-40-37-21安全说明: 26-36-45-1/2-36/37/39-16-33-29-61
危险品运输编号: UN 3267 8/PG 2
WGK Germany : 1
RTECS号: NI7000000
F : 3-10
HazardClass : 8
PackingGroup : III
海关编码: 29332990
N-甲基咪唑 MSDS
1-Methyl-1H-imidazole
N-甲基咪唑性质、用途与生产工艺
化学性质
外观：无色透明液体，熔点：-60℃，沸点：198℃，密度
d20/4=1.036g/ml。

含量：≥99% 。

用途
主要用于环氧树脂和其它树脂的固化剂；用于浇注、粘接和玻璃钢等领域。

用途
有机合成中间体和树脂固化剂、粘合剂等。

可用于浇注、粘接和玻璃钢等领域。

用途
用作有机合成中间体和树脂固化剂、粘合剂等
N-甲基咪唑上下游产品信息
上游原料
咪唑4-氯-3-硝基苯甲酸碳酸二甲酯
下游产品
1-乙基-3-甲基咪唑四氟硼酸盐1-甲基-1H-咪唑-2-甲醛1-甲基-1H-咪唑-2-羰酰氯1-丁基-3-甲基咪唑四氟硼酸盐盐酸萘甲唑啉1-甲基-1H-咪唑-2-甲酸乙酯1-乙基-3-甲基咪唑二氨腈,98%毒死蜱硝唑芬酮1-丁基-3-甲基咪唑溴盐1-丁基-3-甲基咪唑六氟磷酸盐1-甲基-1H-咪唑-2-羧酸1-甲基咪唑-5-甲酰氯盐酸盐1-乙基-3-甲基咪唑啉双(三氟甲基磺酰基)亚胺洛沙坦甲基毒死蜱2-(1-甲基-1H-咪唑-2-基)-2-羰基乙酸乙酯
1-Methylimidazole
From Wikipedia, the free encyclopedia
616-47-7
CHEBI:113454
ChEMBL543
1348
verify (what is ?)
1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colourless liquid that is used as a specialty solvent, a base, and as a precursor to some ionic liquids. It is a fundamental nitrogen heterocycle and as such mimics for various nucleoside bases as well as histidine and histamine,
Contents
[hide]
∙1Basicity
∙2Synthesis
∙3Applications
o 3.1Ionic liquid precursor
∙4See also
∙5References
Basicity[edit]
With the N-methyl group, this particular derivative of imidazole cannot tautomerize. It is slightly more basic than imidazole, as indicated by the pKa's of the conjugate acids of 7.0 and 7.4.[1] Methylation also provides a significantly lower melting point, which makes 1-methylimidazole a useful solvent.
Synthesis[edit]
1-Methylimidazole is prepared mainly by two routes industrially. The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine.[2][3]
(CHO)2 + CH2O + CH3NH2 + NH3→ H2C2N(NCH3)CH + 3 H2O
The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation.[4] Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation.[5][6]
H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I
H2C2(NH)(NCH3)CH + NaOH → H2C2N(NCH3)CH + H2O + NaI Applications[edit]
In the research laboratory, 1-methylimidazole and related derivatives have been used as mimic aspects of diverse imidazole-based biomolecules.
1-Methylimidazole is also the precursor for the synthesis of the methylimidazole monomer of pyrrole-imidazole polyamides. These polymers can selectively bind specific sequences of double-stranded DNA by intercalating in a sequence dependent manner.[7]
Ionic liquid precursor[edit]
1-Methylimidazole alkylates to form dialkyl imidazolium salts. Depending on the alkylating agent and the counteranion, various ionic liquids result, e.g. 1-butyl-3-methylimidazolium hexafluorophosphate ("BMIMPF6"):[8][9]
BASF has used 1-methylimidazole as a means to remove acid during
their industrial-scale production of diethoxyphenylphosphine. In this biphasic acid scavenging using ionic liquids (BASIL) process, 1-methylimidazole reacts with HCl to produce 1-methylimidazolium hydrochloride, a salt that is easily separated and deprotonated to regenerate 1-methylimidazole.[8]
2 MeC3N2H
3 + C6H5PCl2 + 2 C2H5OH → 2 [MeC3N2H4]Cl + C6H5P(OC2H5)2
See also[edit]
4-Methylimidazole。