神经病学英文课件：09 headache
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recurrence after delivery
Psychology
• Depression、serious、 • stress
The exact Βιβλιοθήκη Baiduechanisms of migraine are not known
Vascular theory
Cortical spreading depression（CSD）
continuous headache Cranial/ neck muscle constriction- muscle
constriction headache
Main theory before 1980 years
Cortical spreading depression（CSD）
• generates a wave that slowly spread （2-5mm/min）across cortex from occipital area, and it is followed by a prolonged suppression of cortical bioelectrical activity.
2. The secondary headaches
3. Painful cranial neuropathies, other facial pains and other headaches
Migraine
1
Introduction
2
Definition
3
Cause and Pathogeny
Definition
recurrent
Aura(onethird ):visual
Migraine
one half of the head(or
both)
Nausea, vomiting
A mixture of genetic and environmental factors
50%-80% cases run • 4q21-q28
• it spread to sensory area, activating perivascular and meningeal nociceptors of TVS, followed by headach.
Trigeminovascular system（TVS）
British Association for the Study of Headache-2010
Classification (International Headache
society)
1. The primary headaches:
1. Migraine 2. Tension-type headache 3. cluster headache and Trigeminal autonomic cephalalgias 4. Other primary headache disorders
4
Classification
5
Dignose and Therapy
5
Epidemiological studies
In the Global Burden of Disease Survey 2010, it was ranked as the third most prevalent disorder and seventh-highest specific cause of disability worldwide.
Headache affects nearly everyone at least occasionally. It is one of the most frequent causes of consultation in both general practice and neurological clinics. In its various forms, headache represents an immense socioeconomic burden.
An estimated 190,000 attacks of the UK are experienced every day, with three quarters of those affected reporting disability. Over 100,000 people are absent from work or school because of migraine.
in families
• 10q22
Foods Hormone
• Alcohol, especially red wine and beer、chocolate、 coffee、Citrus fruits
• adolescent females • decreases during pregnancy，
Trigeminovascular system（TVS）
Vascular theory
Intracerebral blood vessel constriction-aura Intracranial/Extracranial blood vessel dilation-
throbbing pain Blood vessel walls aseptic inflammation-
Headache
Introduction
Headache is a non-specific symptom, which means that it has many possible causes, including fatigue and sleep deprivation, stress, the effects of medications and recreational drugs, viral infections and common colds, head injury, rapid ingestion of a very cold food or beverage, dental or sinus issues, and many more.
Psychology
• Depression、serious、 • stress
The exact Βιβλιοθήκη Baiduechanisms of migraine are not known
Vascular theory
Cortical spreading depression（CSD）
continuous headache Cranial/ neck muscle constriction- muscle
constriction headache
Main theory before 1980 years
Cortical spreading depression（CSD）
• generates a wave that slowly spread （2-5mm/min）across cortex from occipital area, and it is followed by a prolonged suppression of cortical bioelectrical activity.
2. The secondary headaches
3. Painful cranial neuropathies, other facial pains and other headaches
Migraine
1
Introduction
2
Definition
3
Cause and Pathogeny
Definition
recurrent
Aura(onethird ):visual
Migraine
one half of the head(or
both)
Nausea, vomiting
A mixture of genetic and environmental factors
50%-80% cases run • 4q21-q28
• it spread to sensory area, activating perivascular and meningeal nociceptors of TVS, followed by headach.
Trigeminovascular system（TVS）
British Association for the Study of Headache-2010
Classification (International Headache
society)
1. The primary headaches:
1. Migraine 2. Tension-type headache 3. cluster headache and Trigeminal autonomic cephalalgias 4. Other primary headache disorders
4
Classification
5
Dignose and Therapy
5
Epidemiological studies
In the Global Burden of Disease Survey 2010, it was ranked as the third most prevalent disorder and seventh-highest specific cause of disability worldwide.
Headache affects nearly everyone at least occasionally. It is one of the most frequent causes of consultation in both general practice and neurological clinics. In its various forms, headache represents an immense socioeconomic burden.
An estimated 190,000 attacks of the UK are experienced every day, with three quarters of those affected reporting disability. Over 100,000 people are absent from work or school because of migraine.
in families
• 10q22
Foods Hormone
• Alcohol, especially red wine and beer、chocolate、 coffee、Citrus fruits
• adolescent females • decreases during pregnancy，
Trigeminovascular system（TVS）
Vascular theory
Intracerebral blood vessel constriction-aura Intracranial/Extracranial blood vessel dilation-
throbbing pain Blood vessel walls aseptic inflammation-
Headache
Introduction
Headache is a non-specific symptom, which means that it has many possible causes, including fatigue and sleep deprivation, stress, the effects of medications and recreational drugs, viral infections and common colds, head injury, rapid ingestion of a very cold food or beverage, dental or sinus issues, and many more.