PS评分标准

功能状态评分(Performance Status,PS)标准Karnofsky评分法（KPS，百分法）

体力状况评分正常，无症状和体征100 能进行正常活动，有轻微症状和体征90

勉强可进行正常活动，有一些症状或体征80

生活可自理，但不能维持正常生活工作70

生活能大部分自理，但偶尔需要别人帮助60

常需人照料50

生活不能自理，需要特别照顾和帮助40

生活严重不能自理30

病重，需要住院和积极的支持治疗20

重危，临近死亡10

死亡0

Zubrod-ECOG-WHO (ZPS，5分法)

体力状况分级正常活动0

症轻状，生活自在，能从事轻体力活动 1

能耐受肿瘤的症状，生活自理，但白天卧床时间不超过50% 2

肿瘤症状严重，白天卧床时间超过5%，但还能起床站立，部分生活自理 3

病重卧床不起 4

死亡 5

KPS评分一般要求不小于70，ZPS评分一般要求不大于2才考虑化疗。Comparison（KPS与ZPS的对应关系）

▪Zubrod 0 equals Karnofsky 100; 90–100

▪Zubrod 1 equals Karnofsky 80–90; 70–80

▪Zubrod 2 equals Karnofsky 60–70; 50–60

▪Zubrod 3 equals Karnofsky 40–50; 30–40

▪Zubrod 4 equals Karnofsky 20–30;10–20

Performance status（PS）

In medicine (oncology and other fields), performance status is an attempt to quantify cancer patients' general well-being and activities of daily life. This measure is used to determine whether they can receive chemotherapy, whether dose adjustment is necessary, and as a measure for the required intensity of palliative care. It is also used in oncological randomized controlled trials as a measure of quality of life.

Scoring systems

There are various scoring systems. The most generally used are the Karnofsky score and

the Zubrod score, the latter being used in publications by the WHO. For children, the Lansky score is used.

Parallel scoring systems include the Global Assessment of Functioning (GAF) score, which

has been incorporated as the fifth axis of the Diagnostic and Statistical Manual (DSM)

of psychiatry.

Karnofsky scoring

The Karnofsky score runs from 100 to 0, where 100 is "perfect" health and 0 is death. Although practitioners occasionally assign performance scores in between standard intervals of 10,

there is no substantiated rationale for this and prognostication is not improved. This scoring system is named after Dr David A. Karnofsky, who described the scale with Dr Joseph H. Burchenal in 1949.

▪100% – normal, no complaints, no signs of disease

▪90% – capable of normal activity, few symptoms or signs of disease

▪80% – normal activity with some difficulty, some symptoms or signs

▪70% – caring for self, not capable of normal activity or work

▪60% – requiring some help, can take care of most personal requirements

▪50% – requires help often, requires frequent medical care

▪40% – disabled, requires special care and help

▪30% – severely disabled, hospital admission indicated but no risk of death

▪20% – very ill, urgently requiring admission, requires supportive measures or treatment

▪10% – moribund, rapidly progressive fatal disease processes

▪0% – death.

ECOG/WHO/Zubrod score

The ECOG score (published by Oken et al. in 1982), also called the WHO or Zubrod score (after C. Gordon Zubrod), runs from 0 to 5, with 0 denoting perfect health and 5 death: Its advantage over the Karnofsky scale lies in its simplicity.