甲磺酸倍他司汀片联合Brandt-Daroff习服训练治疗耳石症复位后残余头晕的效果

2019年10月

甲磺酸倍他司汀片联合Brandt-Daroff 习服训练治疗

耳石症复位后残余头晕的效果

马爱金

（江苏大学附属武进人民医院，江苏常州，213162）

摘要：目的观察甲磺酸倍他司汀片联合Brandt-Daroff 习服训练治疗耳石症复位后残余头晕的效果。方法选取我院2016年3

月至2018年2月收治的48例耳石症复位后残余头晕患者为研究对象，采用随机数字表法将其分为联合组和对照组，各24例。

联合组采用甲磺酸倍他司汀片联合Brandt-Daroff 习服训练治疗，对照组采用甲磺酸倍他司汀片治疗。比较两组临床疗效。结果联合组痊愈率、总有效率显著高于对照组，甲磺酸倍他司汀片应用时间显著短于对照组（P <0.05）。治疗后，两组VSI 、DHI 评分均降低，且联合组低于对照组（P <0.05）；两组眩晕障碍分级显著改善，且联合组均为轻度眩晕障碍，改善程度优于对照组（P <0.05）。结论甲磺酸倍他司汀片联合Brandt-Daroff 习服训练应用于耳石症复位后残余头晕患者，能提高临床痊愈程度，缩短甲磺酸倍他司汀片用药时间，改善患者前庭功能，降低患者眩晕障碍程度。

关键词：耳石症；头晕；Brandt-Daroff 习服训练中图分类号：R764文献标志码：A

文章编号：2096-1413(2019)29-0050-03

DOI :10.19347/ki.2096-1413.201929022作者简介：马爱金（1976-），男，汉族，江苏武进人，副主任医师，学士。研究方向：脑血管疾病的诊治。

Effect of betahistine mesylate tablets combined with Brandt-Daroff exercise on

residual dizziness after reduction of otolithiasis

MA Ai-jin

(Wujin People's Hospital Affiliated to Jiangsu University,Changzhou 213162,China)

ABSTRACT:Objective To observe the effect of betahistine mesylate tablets combined with Brandt-Daroff exercise on residual dizziness after reduction of otolithiasis.Methods Forty -eight patients with residual dizziness after reduction of otolithiasis in our hospital from March 2016to February 2018were selected as the research objects.The patients were divided into combination group and control group by random number table method,with 24cases in each group.The combination group was treated with betahistine mesylate tablets combined with Brandt-Daroff exercise,while the control group was treated with betahistine mesylate tablets.The clinical effects of the two groups were compared.Results The cure rate and total effective rate of treatment in the combination group were significantly higher than those in the control group,and the application time of betahistine mesylate tablets was significantly shorter than that in the control group (P <0.05).After treatment,the scores of VSI and DHI in both groups decreased,and those in the combination group were lower than the control group (P <0.05);the grades of vertigo disorder in the two groups significantly improved,and those in the combination group were mild vertigo disorder,and the improvement degree was better than that in the control group (P <0.05).Conclusion Betahistine mesylate tablets combined with Brandt-Daroff exercise can improve the clinical recovery of patients with dizziness after otolithiasis reduction,reduce the duration of betahistine mesylate tablets,improve vestibular function and reduce the degree of dizziness disorder of patients.KEYWORDS:otolithiasis;dizziness;Brandt-Daroff exercise

临床医学

耳石症手法复位后仍存在60%以上的患者残余头晕症状，部分患者甚至会产生醉酒感、晕车感，甚至伴发紧张、焦虑等情绪[1]。甲磺酸倍他司汀片具有改善脑血流，松弛内耳毛细血管前括约肌的作用，不能根治耳石症复位后头晕，且存在剂量依赖性[2]。Brandt-Daroff 习服训练用于半规管耳石症，能够减少残余头晕症状、眩晕的复发[3]。本研究旨在明确甲磺酸倍他司汀片联合Brandt-Daroff 习服训练的必要性及临床疗效，现报道如下。1资料与方法1.1一般资料

选取我院2016年3月至2018年2月就诊的耳石症复位

后残余头晕患者48例作为研究对象，采用随机数字表法将其均分为联合组和对照组，各24例。联合组男10例，女14例；年龄40~70岁，平均年龄（55.87±6.28）岁；病程1~15d ，平均病程（10.29±4.72）d ；前庭功能减弱10例，正常14例。对照组男11例，女13例；年龄40~71岁，平均年龄（55.91±6.34）岁；病程1~15d ，平均病程（10.11±4.83）d ；前庭功能减弱11例，正常13例。两组性别、年龄、病程、前庭功能比较均无显著差异（P >0.05），具有可比性。本研究经医院伦理委员会审议并通过，患者对本研究知情并签署知情同意书。

纳入标准：①符合中华医学会耳鼻咽喉科学分会2007年良性阵发性位置性眩晕（BPPV ）的诊断标准；②年龄18~75岁；③行手法复位后仍存在头晕症状。

排除标准：①存在精神、感觉异常或伴发颅脑损伤的患

者；②伴发其他前庭系统疾病的患者，如梅尼埃病等；③应用

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