食物过敏源管理
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Allergen Management 过敏物管理
AFS-China
Sep.2008
Allergen Management过敏物管理
Allergies of all types have been increasing in the course of the last decades. Currently, up to 1/3 of the people in Western countries are affected by this problem.在过去几十年里，各种类型的过敏反应一直 在上升。目前，在西方国家，有三分之一的人受到这 个问题的困扰。 Allergic reactions to food are not as frequent. Food allergy occurs in about 1-2% of adults and 5-8% of infants and small children. 对食品的过敏反应却没有这么多。由食品引发的过敏反 应在成人中约占1-2%，在婴儿及小孩中约占5-8%。
到免疫系统。不管过敏反应的人知道与否，一但与过敏物接 触，过敏反应就会发生。
Can react very quickly过敏反应可以发病很快 Very tiny dose of allergen could trigger allergy reaction
非常小剂量的致敏物就可引发过敏反应
In extreme case ,lead to death极端情况下，会导致死亡
重.
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
In addition to true Food Allergy,there are also food hypersensitive such as coeliac disease or food intolerance: 除了真正的食品过敏症,还有食品敏感症(如腹部疾病) 和食物不耐受症 Adverse reaction due to deficiency in digestive system or metabolic system : such as lactose intolerance它们
3. Milk and product thereof奶及其产品 4. Eggs and product thereof蛋及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen:
5. Soya and product there of大豆及其产品 6. Fish and product there of鱼及其产品 7. Crustacea and product there of甲壳动物及 其产品 8. Wheat and other gluten containing cereals , product there of小麦及其他含面筋类谷物 及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物: 1. Peanut and product thereof花生及其产品 2. Tree nut and product thereof木生坚果类 及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
What is allergy?什么是过敏？
Allergies are one kind of adverse reaction to substances involving immune system.过敏是涉及到免疫系统的对外 界物质的一种不良反应。 There are many kinds of allergies : allergy to pollen , lotion ,drug, food etc.过敏反应有各种类型：对花粉，沐 浴液，药品，食品过敏等
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Food Allergy食品过敏症:
Food allergies are well-defined adverse reaction to substances present in food ,involving the immune system,most often they are mediated by immunoglobulin E(lgE).Food allergens are usually proteins or protein fragments to which allergic individuals have previously been sensitized食品过敏症是准确定义的对食品中存 在物质的不良反应，它涉及到免疫系统，在大多数情况下， 引发免疫球蛋白E的反应。食品中的致敏物通常是蛋白或蛋白 片段，过敏个体对它曾经敏感。
致敏物引发（例如：曾经有报道，0.0007毫克的花生在敏感人 体中引发过敏反应)
Onset is often extremely rapid after /during ingestion通
常在食用过程中或食用后极快地发病
Reaction may be slight or severe反应程度有时很轻,有时很
的死亡事肉煎饼
Death in Canada: Peanut-allergic woman bought “Marcipan” containing cake which contained peanuts instead of almonds发生在加拿大的死亡事件:对花生过敏的一位
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Hundreds of food allergens have been reported已报导的食 品致敏物已经有上百种. But: >90% of the relevant incidents are caused by 8 types of food但是超过90%的相关事故是由8大类食品导致的 There are many allergens that often cause only mild reactions有许多致敏物常常只是导致轻微的过敏反应 International consensus: the “big 8” are most relevant (Codex list), 11 now in EU.国际上通常认为: 这8类是最 相关的(国际法典的列表),在欧洲,现在列出了十一种
女士买了含“Marcipan” 的饼,实际上它含有花生而不是杏仁.
Death in USA: Walnut-allergic man ate a walnut containing Veggie-Burger at a friend‘s place发生在美国的死
亡事件:对胡桃过敏的一位男士在朋友处吃了含胡桃的素饼
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物: So far, no precise threshold for maximum acceptable allergen contaminations have been assessed.目前,尚没有对致敏物污染的最大可接受
限值作出评估.
Yet there are some reference values但是,有一些
参考值:
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
(rye黑麦,barley大麦,oats燕麦,spelt佩斯耳特小 麦, kamut卡姆小麦 and their cross-bred varieties 及他们的杂交品种)
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Other Food Allergen其他的食品类(或相关)致敏 物:
(almonds杏仁,Brazil nuts 巴西坚果,cashew腰 果,chest nuts栗子, hazelnuts 榛子, Macadamia nuts 澳大利亚坚果,pecans 美洲山核桃, pine nuts 松果,pistachio阿月浑子果 ,walnuts 胡桃, Queensland nut 昆士兰坚果)
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物:
Most of the severe reaction are limited to peanut,tree nuts,cow milk,eggs, soya,fish, crustacea,wheat . Peanut allergy is associated with most of the very severe and potentially fatal reactions.大多严重的过敏反应都限于 花生,木生坚果,牛奶,蛋,大豆，鱼,甲壳动物,小麦. 而 花生又与大多非常严重和潜在致死过敏反应相关. A few milligrams ingested are able to trigger acute reaction几毫克的摄入量就可以引发严重的过敏反应
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Food Allergy食品过敏症:
Can be triggered by very small quantity of allergens( exa.0.0007mg peanut trigger allergic reaction in sensitive personnel is reported)它可以由非常小剂量的
Sesame and product there of芝麻及其产品 Celery and product there of芹菜及其产品 Mustard and product there of芥菜/芥末及其产品 Mollusk and product there of软体动物及其产品 Lupin and product there of羽扁豆及其产品 Sulfite硫酸盐 (SO2 ,above 10mg/kg以二氧化硫计 超 过10毫克/公斤)
引发的不良反应是由于消化系统或新陈代谢系统的 缺陷引起的:如乳糖不耐受症
Fatal cases: due to lack of information 由于缺乏信 息导致的死亡事件
Death in Sweden: Soya-allergic pupil ate soyaburger in school canteen which was called “hamburger” 发生在瑞典
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Allergy character过敏反应的特征:
It involves immune system,whatever the allergy people know or not , once contact, reaction will happen它牵扯
AFS-China
Sep.2008
Allergen Management过敏物管理
Allergies of all types have been increasing in the course of the last decades. Currently, up to 1/3 of the people in Western countries are affected by this problem.在过去几十年里，各种类型的过敏反应一直 在上升。目前，在西方国家，有三分之一的人受到这 个问题的困扰。 Allergic reactions to food are not as frequent. Food allergy occurs in about 1-2% of adults and 5-8% of infants and small children. 对食品的过敏反应却没有这么多。由食品引发的过敏反 应在成人中约占1-2%，在婴儿及小孩中约占5-8%。
到免疫系统。不管过敏反应的人知道与否，一但与过敏物接 触，过敏反应就会发生。
Can react very quickly过敏反应可以发病很快 Very tiny dose of allergen could trigger allergy reaction
非常小剂量的致敏物就可引发过敏反应
In extreme case ,lead to death极端情况下，会导致死亡
重.
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
In addition to true Food Allergy,there are also food hypersensitive such as coeliac disease or food intolerance: 除了真正的食品过敏症,还有食品敏感症(如腹部疾病) 和食物不耐受症 Adverse reaction due to deficiency in digestive system or metabolic system : such as lactose intolerance它们
3. Milk and product thereof奶及其产品 4. Eggs and product thereof蛋及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen:
5. Soya and product there of大豆及其产品 6. Fish and product there of鱼及其产品 7. Crustacea and product there of甲壳动物及 其产品 8. Wheat and other gluten containing cereals , product there of小麦及其他含面筋类谷物 及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物: 1. Peanut and product thereof花生及其产品 2. Tree nut and product thereof木生坚果类 及其产品
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
What is allergy?什么是过敏？
Allergies are one kind of adverse reaction to substances involving immune system.过敏是涉及到免疫系统的对外 界物质的一种不良反应。 There are many kinds of allergies : allergy to pollen , lotion ,drug, food etc.过敏反应有各种类型：对花粉，沐 浴液，药品，食品过敏等
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Food Allergy食品过敏症:
Food allergies are well-defined adverse reaction to substances present in food ,involving the immune system,most often they are mediated by immunoglobulin E(lgE).Food allergens are usually proteins or protein fragments to which allergic individuals have previously been sensitized食品过敏症是准确定义的对食品中存 在物质的不良反应，它涉及到免疫系统，在大多数情况下， 引发免疫球蛋白E的反应。食品中的致敏物通常是蛋白或蛋白 片段，过敏个体对它曾经敏感。
致敏物引发（例如：曾经有报道，0.0007毫克的花生在敏感人 体中引发过敏反应)
Onset is often extremely rapid after /during ingestion通
常在食用过程中或食用后极快地发病
Reaction may be slight or severe反应程度有时很轻,有时很
的死亡事肉煎饼
Death in Canada: Peanut-allergic woman bought “Marcipan” containing cake which contained peanuts instead of almonds发生在加拿大的死亡事件:对花生过敏的一位
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Hundreds of food allergens have been reported已报导的食 品致敏物已经有上百种. But: >90% of the relevant incidents are caused by 8 types of food但是超过90%的相关事故是由8大类食品导致的 There are many allergens that often cause only mild reactions有许多致敏物常常只是导致轻微的过敏反应 International consensus: the “big 8” are most relevant (Codex list), 11 now in EU.国际上通常认为: 这8类是最 相关的(国际法典的列表),在欧洲,现在列出了十一种
女士买了含“Marcipan” 的饼,实际上它含有花生而不是杏仁.
Death in USA: Walnut-allergic man ate a walnut containing Veggie-Burger at a friend‘s place发生在美国的死
亡事件:对胡桃过敏的一位男士在朋友处吃了含胡桃的素饼
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物: So far, no precise threshold for maximum acceptable allergen contaminations have been assessed.目前,尚没有对致敏物污染的最大可接受
限值作出评估.
Yet there are some reference values但是,有一些
参考值:
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
(rye黑麦,barley大麦,oats燕麦,spelt佩斯耳特小 麦, kamut卡姆小麦 and their cross-bred varieties 及他们的杂交品种)
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Other Food Allergen其他的食品类(或相关)致敏 物:
(almonds杏仁,Brazil nuts 巴西坚果,cashew腰 果,chest nuts栗子, hazelnuts 榛子, Macadamia nuts 澳大利亚坚果,pecans 美洲山核桃, pine nuts 松果,pistachio阿月浑子果 ,walnuts 胡桃, Queensland nut 昆士兰坚果)
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Major Food Allergen主要的食品类致敏物:
Most of the severe reaction are limited to peanut,tree nuts,cow milk,eggs, soya,fish, crustacea,wheat . Peanut allergy is associated with most of the very severe and potentially fatal reactions.大多严重的过敏反应都限于 花生,木生坚果,牛奶,蛋,大豆，鱼,甲壳动物,小麦. 而 花生又与大多非常严重和潜在致死过敏反应相关. A few milligrams ingested are able to trigger acute reaction几毫克的摄入量就可以引发严重的过敏反应
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Food Allergy食品过敏症:
Can be triggered by very small quantity of allergens( exa.0.0007mg peanut trigger allergic reaction in sensitive personnel is reported)它可以由非常小剂量的
Sesame and product there of芝麻及其产品 Celery and product there of芹菜及其产品 Mustard and product there of芥菜/芥末及其产品 Mollusk and product there of软体动物及其产品 Lupin and product there of羽扁豆及其产品 Sulfite硫酸盐 (SO2 ,above 10mg/kg以二氧化硫计 超 过10毫克/公斤)
引发的不良反应是由于消化系统或新陈代谢系统的 缺陷引起的:如乳糖不耐受症
Fatal cases: due to lack of information 由于缺乏信 息导致的死亡事件
Death in Sweden: Soya-allergic pupil ate soyaburger in school canteen which was called “hamburger” 发生在瑞典
Background information of allergy & allergen-过敏症及过敏物背景信息介绍
Allergy character过敏反应的特征:
It involves immune system,whatever the allergy people know or not , once contact, reaction will happen它牵扯