瓦赫宁根大学动科ppt(Wouter Hazeleger)
合集下载
相关主题
- 1、下载文档前请自行甄别文档内容的完整性，平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益，请联系客服反馈,我们会尽快为您处理(人工客服工作时间：9:00-18:30)。
源自文库
Litter size in pigs
• • • • Number of ovulations Fertilisation Embryonic mortality (< Day 35) Foetal mortality (> Day 35)
Mechanism Embryonic mortality
• Deviating embryonic development
• Deviating uterus development (regulated by progesterone (CL) and embryonic signals)
Day 3
Pharazyn et al. 1992
Conclusions Embryonic mortality
Embryonic developement and mortality
Wouter Hazeleger
Topics
• Embryonic development • Regulation pregnant/ non-pregnant (maternal recognition of pregnancy) • Embryonic survival (+ affecting factors)
Fig. 13-6
Hormones schedule
Mechanism Embryonic mortality
• Asynchrony: embryo and uterus not synchronously • Deviating uterus development • Deviating embryo development
• Genetics • Insemination • Oocyr quality (nutrition !!) • Uterus functioning (nutrition!!) • Stress ????
Morula
Blastocyst
Dag 5 flushing fertilised (blastocysten)+ unfertilised
Hatching (day 6-7)
Day 11 embryos
Day 13-14 implantations
Day 17 embryo
Day 18 embryo + allantois
• Asynchrony: embryo and uterus development not synchronously
Dzuik 1987
Fig. 13-3
Egg with spermcells (Hoechst (DNA) staining)
4-cel stage
Unfertilised oocyt
Day 19 embryo
Day 25 embryo
Day 35 embryo / foetus
Day 70 foetuses
Maternal recognition of pregnancy (pregnant / non-pregnant): Day 11 embryos
Fig. 13-6
Variation in embryonic developement
• Genetics • Inseminatiion • Oocyt quality (nutrition !!)
Mechanism Embryonic mortality
• Asynchrony: embryo and uterus not synchronously
Causes deviating embryos
• Genetics (within litter variation) • Insemination
Soede et al. 1993
• OOCYTE quality
Soede et al. 1993
Grant et al. 1989
Ferguson et al. 2003
Litter size in pigs
• • • • Number of ovulations Fertilisation Embryonic mortality (< Day 35) Foetal mortality (> Day 35)
Mechanism Embryonic mortality
• Deviating embryonic development
• Deviating uterus development (regulated by progesterone (CL) and embryonic signals)
Day 3
Pharazyn et al. 1992
Conclusions Embryonic mortality
Embryonic developement and mortality
Wouter Hazeleger
Topics
• Embryonic development • Regulation pregnant/ non-pregnant (maternal recognition of pregnancy) • Embryonic survival (+ affecting factors)
Fig. 13-6
Hormones schedule
Mechanism Embryonic mortality
• Asynchrony: embryo and uterus not synchronously • Deviating uterus development • Deviating embryo development
• Genetics • Insemination • Oocyr quality (nutrition !!) • Uterus functioning (nutrition!!) • Stress ????
Morula
Blastocyst
Dag 5 flushing fertilised (blastocysten)+ unfertilised
Hatching (day 6-7)
Day 11 embryos
Day 13-14 implantations
Day 17 embryo
Day 18 embryo + allantois
• Asynchrony: embryo and uterus development not synchronously
Dzuik 1987
Fig. 13-3
Egg with spermcells (Hoechst (DNA) staining)
4-cel stage
Unfertilised oocyt
Day 19 embryo
Day 25 embryo
Day 35 embryo / foetus
Day 70 foetuses
Maternal recognition of pregnancy (pregnant / non-pregnant): Day 11 embryos
Fig. 13-6
Variation in embryonic developement
• Genetics • Inseminatiion • Oocyt quality (nutrition !!)
Mechanism Embryonic mortality
• Asynchrony: embryo and uterus not synchronously
Causes deviating embryos
• Genetics (within litter variation) • Insemination
Soede et al. 1993
• OOCYTE quality
Soede et al. 1993
Grant et al. 1989
Ferguson et al. 2003