脑卒中患者体感功能恢复过程中的大脑皮质激活

脑卒中患者体感功能恢复过程中的大脑皮质激活

脑卒中患者若出现体感功能障碍会对日常独立生活能力造成影响。因此，理解体感功能障碍恢复机制对于获得更好的功能康复结局很重要。以往研究已证实，体感功能恢复的机制涉及损伤侧初级和双侧二级体感皮质功能重组。但基于脑卒中后体感功能恢复过程的神经机制仍不清楚。韩国岭南大学Yong Hyun Kwon教授及大邱韩医大学的Mi Young Lee教授在《中国神经再生研究（英文版）》杂志2014年8月第15期发表文章，报道了1例有严重体感功能障碍的脑卒中患者在体感功能恢复过程中，经功能MRI观察到的大脑皮质激活模式变化。结果发现，脑卒中患者在发病后5周至6个月，体感功能逐渐恢复的过程中，大脑皮质激活区从损伤侧初级运动感觉皮质转移至健侧初级运动感觉皮质和辅助运动区。转移后的大脑皮质激活区与健康人的激活模式基本相同。说明随着脑卒中患者感觉功能的恢复，大脑激活模式逐渐趋向正常。

Article: " Changes in cortical activation patterns accompanying somatosensory recovery in a stroke patient: a functional magnetic resonance imaging study" by Yong Hyun Kwon1, Mi Young Lee2 (1 Department of Physical Therapy, Yeungnam University College, Namgu, Daegu, 705-703, Republic of Korea; 2 Department of Physical Therapy, College of Health and Therapy, Daegu Haany University, Gyeongsan-si, Gyeongsangbuk-do, 712-715, Republic of Korea)

Kwon YH, Lee MY. Changes in cortical activation patterns accompanying somatosensory recovery in a stroke patient: a functional magnetic resonance imaging study. Neural Regen Res. 2014;9(15):1485-1488.

欲获更多资讯：

Neural Regen Res

Cortical activation patterns accompanying somatosensory recovery in a stroke patient

Patients with somatosensory dysfunction show negative effects on motor control, and it sometimes becomes difficult to perform daily activities independently. Therefore, a better understanding of the recovery mechanism underlying somatosensory dysfunction is necessary for a successful neurorehabilitation outcome.Previous studies have studied the mechanism underlying somatosensory recovery, which is related to reorganization of the ipsilesional primary and bilateral secondary somatosensory cortices.However, the neural mechanism underlying the recovery of somatosensory function following stroke is unclear. Prof. Yong Hyun Kwon (Yeungnam University College in Republic of Korea) and Mi Young Lee

(Daegu Haany University in Republic of Korea) reported a stroke patient with severe somatosensory dysfunction showing changes in cortical activation patterns following somatosensory recovery using functional magnetic resonance imaging, which has been published in the Neural Regeneration Research (Vol. 9, No. 15, 2014). Regarding changes in brain activation patterns between the two fMRI measurements, ipsilesional primary secondary somatosensory cortices primary

sensory-motor cortex ipsilesional to the affected hand in the pre-fMRI scans disappeared, whereas activation of the contralateral primary sensory-motor cortex and supplementary motor area was newly observed in the post-fMRI scans at 5 weeks and 6 months after stroke onset. These results suggest that brain activation patterns similar to the control subjects showed a tendency to be normalized according to improvement of actual sensory function.

Article: " Changes in cortical activation patterns accompanying somatosensory recovery in a stroke patient: a functional magnetic resonance imaging study" by Yong Hyun Kwon1, Mi Young Lee2 (1 Department of Physical Therapy, Yeungnam University College, Namgu, Daegu, 705-703, Republic of Korea; 2 Department of Physical Therapy, College of Health and Therapy, Daegu Haany University, Gyeongsan-si, Gyeongsangbuk-do, 712-715, Republic of Korea)

Kwon YH, Lee MY. Changes in cortical activation patterns accompanying somatosensory recovery in a stroke patient: a functional magnetic resonance imaging study. Neural Regen Res. 2014;9(15):1485-1488.