新技术对细胞形态学的帮助(贝克曼库尔特)
- 1、下载文档前请自行甄别文档内容的完整性,平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益,请联系客服反馈,我们会尽快为您处理(人工客服工作时间:9:00-18:30)。
Innovations Leading the Way to Our Future
科技创新引导未来之路
贝克曼库尔特公司市场部
梁彬
Apr,2009
Joseph R. Coulter, Jr.
1924-1995
Wallace H. Coulter
1913-1998
The Beginning of
Clinical Cellular Analysis
临床自动血细胞分析的开端
As a particle passes through the aperture, it creates a resistance. The bigger the particle, the more the resistance, the greater the voltage. Each voltage spike is directly proportional to the size of the cell.
颗粒通过小孔时,产生阻抗。颗粒越大产生的阻抗和电压越大。电压的大小直接与细胞的大小呈比例。
1968 Model S
Era of Invention Hematology
血液学检验创新的时代
1953 Model A
Electronically measured cells 电子细胞计数仪
1977 S Plus
Automated platelet count 血小板自动计数仪
1975TPS
Era of Invention Flow Cytometry
流式细胞仪发明的时代
Clinical Flow Cytometer 临床流式细胞仪
1984 Epics C
Two Parameter Cell Sorting 两参数细胞仪
1987 Q Prep
Automated Sample Prep 自动样品制备仪
2000 Gen•S Cell
•AccuFlex 精敏调节系统
•Decision Support Rules 决策支持系统•IntelliKinetics 智能动力系统
•Automated Reticulocytes 自动网织红计数•
Integrated SlideMaker and SlideStainer 自动推片机和自动染片机
1985 Hematology Flow Cytometry 流式细胞术血液分析仪
Integration of flow cytometry into a hematology analyzer 流式细胞术整合到血液分析仪
Scientific Marketing
Productivity Redefined 检测能力更新
Hematology LH 700 Series LH700 系列血液分析仪
• Random Access 随机检测 • AccuCount Technology 智能微数技术 • Extended Linearity 扩展线性范围 • NRBC count 计数有核红细胞 • Correct WBC count for Interference
纠正干扰白细胞计数的影响因素
• Decreased need for Manual Review
减少手工复查 • Cell Population Data (CPD) 白细胞群落参数 • Body Fluid Analysis 体液检测
For Research Use Only. Not for use in diagnostic procedures
Scientific Marketing
改善病人健康和减少医疗费用
Analytical Systems Assays
Right Result Right Patient Right Time
Data Management Systems
For Research Use Only. Not for use in diagnostic procedures
Sample Management Systems
Scientific Marketing
TAT 有效检测时间
• TAT: Turnaround time • 如何缩短TAT?
– – – – 仪器速度? 准确性 假阴性、假阳性 全面性 项目参数、报警 方便性 自动决策筛选
For Research Use Only. Not for use in diagnostic procedures
Scientific Marketing
内容
• 血细胞分析的发展历程 • VCS白细胞分类新参数及应用 • 血细胞分析自动化
For Research Use Only. Not for use in diagnostic procedures
Scientific Marketing
V
WBC Diff Technology
白细胞分类技术
C
S
VCS
WBC in “near native state” 处于“近自然状态”的白细胞
For Research Use Only. Not for use in diagnostic procedures
Scientific Marketing
VCS技术
Neut
• 独特的双试剂系 统
– 红细胞溶解剂:通
过渗透压差溶解红细 胞;
Eo
Lymph
– 溶解终止液:令白
细胞恢复“接近原态” 大小。
RBC
W Swelling BC
W Shrinkage BC
Lysis Nuclei
Blood
RBC Swelling ErythroLyse
RBC ghost, fragment, dis olve StabiLyse
C O U N T
For Research Use Only. Not for use in diagnostic procedures