左炔诺孕酮宫内缓释系统(曼月乐环)治疗子宫内膜增生分析
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CHINA MEDICINE AND PHARMACY Vol.9 No.4 February 2019
87
2019年2月第9卷第4期
·妇产医学·
左炔诺孕酮宫内缓释系统(曼月乐环)
治疗子宫内膜增生分析
田 寒
广东省惠州市中医医院妇产科,广东惠州 516000
[摘要] 目的 探讨子宫内膜增生患者接受左炔诺孕酮宫内缓释系统(曼月乐环)治疗的价值。 方法 选取100例惠州市中医医院妇产科子宫内膜增生患者为研究对象,时间为2017年6月~2018年6月,随机分组,其中对照组接受孕激素治疗,实验组则接受左炔诺孕酮宫内缓释系统(曼月乐环)治疗,分析两组子宫内膜增生患者治疗的结果。结果 两组治疗12个月后的月经量以及子宫内膜厚度均较治疗前明显降低,其中实验组子宫内膜增生患者治疗12个月后的月经量、子宫内膜厚度低于对照组,差异具有统计学意义(P <0.05);两组子宫内膜增生患者的不良反应几率相比,差异无统计学意义(P >0.05)。 结论 子宫内膜异位症患者接受左炔诺孕酮宫内缓释系统(曼月乐环)治疗,可取得较好的效果。
[关键词] 左炔诺孕酮宫内缓释系统(曼月乐环);子宫内膜增生;孕激素受体;雌激素受体[中图分类号] R711.74 [文献标识码] A [文章编号] 2095-0616(2019)04-87-03
Analysis of levonorgestrel releasing intrauterine system
(intrauterine device) for endometrial hyperplasia
TIAN Han
Obstetrics and Gynecology Department, Huizhou Traditional Chinese Medicine Hospital, Guangdong, Huizhou 516000, China
[Abstract] Objective To explore the value of levonorgestrel releasing intrauterine system (intrauterine device) in patients with endometrial hyperplasia. Methods 100 patients with endometrial hyperplasia who admitted to our hospital from June 2017 to June 2018 were randomly divided into experimental group and control group. The control group treated with progesterone, while the experimental group received levonorgestrel releasing intrauterine system (intrauterine device) treatment. The treatment results of endometrial hyperplasia patients between the two groups were analyzed. Results The menstrual volume and endometrial thickness of the two groups after 12 months of treatment were significantly lower than those before treatment, and the menstrual volume and endometrial thickness of the experimental group after 12 months of treatment were lower than those of the control group, with statistically significant differences (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P >0.05). Conclusion The patients with endometriosis received the treatment of levonorgestrel releasing intrauterine system (intrauterine device), and good results can be achieved.
[Key words] Levonorgestrel releasing intrauterine system (intrauterine device); Endometrial hyperplasia; Progesterone receptor; Estrogen receptor
子宫内膜增生是常见的妇科疾病,可导致患者患者出现子宫异常出血,包括阴道不规则流血、经期延长、月经过频、经量过多等[1],以往为子宫内膜增生患者实施治疗,主要是通过孕激素口服的方式进行干预,虽然可取得一定的效果,但是患者需要长时间接受药物治疗,且存在存在突破性出血的危险,疾病复发率较高,且会导致患者的肝肾功能受到损害,影响其治疗的依从性[2-3]。随着医疗研究的不断深入,发现左炔诺孕酮宫内缓释系统(曼月乐环)在子宫内膜增生患者治疗中应用,可取得一定的效果。本文主要对子宫内膜增生患者接受左
炔诺孕酮宫内缓释系统(曼月乐环)治疗的价值作观察分析,报道如下。1 资料与方法1.1 一般资料
以100例惠州市中医医院妇产科子宫内膜增生患者为研究对象,时间为2017年6月~2018年6月,随机分为两组。实验组中,50例患者的年龄范围为33~51岁,平均(40.8±6.3)岁;病程范围为1~10年,平均(5.23±3.20)年;平均孕次为(2.36±0.20)次,平均产次为(1.33±0.58)次,BMI 均值为(25.69±3.35)kg/m 2;39例患者为单纯性子