【WO2019185524A1】掺入生物活性无机添加剂的热塑性材料【专利】

(

(51)International Patent Classification:

TR),OAPI (BF,BJ,CF,CG,Cl,CM,GA,GN,GQ,GW,A61L 27/18(2006.01)A61L 27/48(2006.01)

KM,ML,MR,NE,SN,TD,TG).

A61L 27/46(2006.01)A61L 27/56(2006.01)

(21)International Application Number:Declarations under Rule 4.17:PCT/EP2019/057400

—as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H))(22)International Filing Date:

25March 2019(25.03.2019)Published:

—with international search report (Art.21(3))

(25)Filing Language:

English (26)Publication Language:

English (30)Priority Data:

62/648,37826March 2018(26.03.2018)US

(71)Applicant:EVONIK DEGUSSA GMBH [DE/DE];

Rellinghauser Stralk 1-11,45128Essen (DE).

(72)Inventors:PRABHU,Balaji;1000Birchal Ln.,Apt.302,

Hoover,Alabama 35226(US).DADSETAN,Mahrokh;

925Stoneriver Dr.,Birmingham,Alabama 35211(US).

BODHAK,Subhadip;1615Wildwood Crossings,Birm¬

ingham,Alabama 35211(US).KARAU,Andreas;Am

Langen Steg 32A,63571Gelnhausen (DE).KNEBEL,

Marc;Ahornstralk 1,68542Heddesheim (DE).LIZIO,

Rosario;Beethovenstrasse 15,64807Dieburg (DE).VON

KARSA-WILBERFORCE,Samuel;Hauffstrasse 30,

63071Offenbach (DE).

(74)Agent:EVONIK PATENT ASSOCIATION;c/o Evonik

Industries AG /IP Management,Bau 1042A /PB 15,Paul-

Baumann-Stralk 1,45772Marl (DE).

(81)Designated States (unless otherwise indicated,for every

kind o f national protection available):AE,AG,AL,AM,

AO,AT,AU,AZ,BA,BB,BG,BH,BN,BR,BW,BY,BZ,

CA,CH,CL,CN,CO,CR,CU,CZ,DE,DJ,DK,DM,DO,

DZ,EC,EE,EG,ES,FI,GB,GD,GE,GH,GM,GT,HN,

HR,HU,ID,IL,IN,IR,IS,JO,JP,KE,KG,KH,KN,KP,

KR,KW,KZ,LA,LC,LK,LR,LS,LU,LY,MA,MD,ME,

MG,MK,MN,MW,MX,MY,MZ,NA,NG,NI,NO,NZ,

OM,PA,PE,PG,PH,PL,PT,QA,RO,RS,RU,RW,SA,

SC,SD,SE,SG,SK,SL,SM,ST,SV,SY,TH,TJ,TM,TN,

TR,TT,TZ,UA,UG,US,UZ,VC,VN,ZA,ZM,ZW.

(84)Designated States (unless otherwise indicated,for every

kind o f regional protection available):ARIPO (BW,GH,

GM,KE,LR,LS,MW,MZ,NA,RW,SD,SL,ST,SZ,TZ,

UG,ZM,ZW),Eurasian (AM,AZ,BY,KG,KZ,RU,TJ,

TM),European (AL,AT,BE,BG,CH,CY,CZ,DE,DK,

EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,

MC,MK,MT,NL,NO,PL,PT,RO,RS,SE,SI,SK,SM,

(54)Title:THERMOPLASTIC MATERIALS INCORPORATING BIOACTIVE INORGANIC ADDITIVES

(57)Abstract:Composite materials comprising thermoplastic polymeric material such as polyaryletherketones (PAEKs)and inorganic additive species serving to increase the processing and resultant mechanical,thermal,and biological properties of said thermoplastic polymeric material which may be subsequently used in various medical applications after the two materials are mixed through thermal processing methods.The inorganic additive species may be a calcium salt,and may include fluorine ions.